ABSTRACT
The immunity of patients with infiltrative and disseminated pulmonary tuberculosis may be characterized as secondary immunodeficiency by the T-cell type and neutrophilic phagocytic activity. Myelopid has a stimulating effect on the humoral and cellular immunities, restores the baseline reduced functional parameters of neutrophilic activity.
Subject(s)
Activins , Adjuvants, Immunologic/therapeutic use , Immunologic Deficiency Syndromes/therapy , Oligopeptides , Peptides/therapeutic use , Tuberculosis, Pulmonary/complications , Adult , Antitubercular Agents/therapeutic use , Follow-Up Studies , Humans , Immunoglobulin A/immunology , Immunoglobulin G/immunology , Immunologic Deficiency Syndromes/etiology , Immunologic Deficiency Syndromes/immunology , Middle Aged , Neutrophil Activation/drug effects , Treatment Outcome , Tuberculosis, Pulmonary/drug therapy , Tuberculosis, Pulmonary/immunologyABSTRACT
The effectiveness of drug and surgical treatments for chronic destructive types of periodontitis was examined in 64 patients with chronic obstructive bronchitis by using clinical, X-ray, and immunological data. The findings suggest that surgical management is more preferable for treating prolonged destructive periodontitis in patients with chronic bronchitis.
Subject(s)
Bronchitis/complications , Periapical Periodontitis/therapy , Adult , Antibody Formation , Apicoectomy , Bronchitis/immunology , Chronic Disease , Female , Humans , Immunity, Cellular , Immunologic Deficiency Syndromes/complications , Immunologic Deficiency Syndromes/immunology , Male , Periapical Periodontitis/immunology , Saliva/immunologySubject(s)
Graft vs Host Reaction , Lymph Nodes/physiology , Spleen/physiology , Thymus Gland/physiology , Animals , Female , Mice , RegenerationABSTRACT
Acute hemorrhage of varying severity was produced in (CBA x C57BL/6)F1 hybrids. Then it was followed by the induced systemic graft-versus-host reaction (GVHR). The increased intensity of the hemorrhage made the course of the systemic GVNR more severe. The 10th day after GVHR induction no significant differences were found in the peripheral blood of experimental or control animals. However, the hybrids demonstrated a significant rise in the number of exogenic stem cells in the spleens during hemopoietic regeneration and diminution of the immunocompetence of splenic T cells.
Subject(s)
Graft vs Host Reaction , Hematopoiesis , Regeneration , Spleen/physiology , Acute Disease , Animals , Colony-Forming Units Assay , Female , Hemorrhage/physiopathology , Mice , Mice, Inbred C57BL , Mice, Inbred CBAABSTRACT
Partial splenectomy was performed in CBAXXC57BL/6/F1 hybrids 2, 12, 15 and 20 days before the graft-versus-host reaction induction (GVHR) and 2, 10 days after administration of parenteral immunocompentent cells. The recipients with the intact spleen or complete splenectomy and sham operated recipients served as control. Hybrids with the regenerating spleen were more resistant to GVHR within 12 days of regeneration, while splenectomy increased hybrid resistance to GVHR only when performed 2 days before or 2 days following the GVHR induction.
