ABSTRACT
The peripheral cemento-ossifying fibroma (PCOF) lesion primarily affects females in their second decade of living. These lesions are more frequently associated with the gingival margin, the anterior surface of the molars, and the maxilla. On clinical examination, PCOF typically appears as a well-differentiated, slowly expanding gingival mass in the interdental papilla region that is less than 2 cm in size. The surface may seem ulcerated, the base may be sessile or sometimes pedunculated, and the colour is either the same as the gingiva or reddish. The histological examination, which identifies cellular connective tissue and the focal presence of bone or calcifications, provides the basis for the final diagnosis. Treatment modalities for the PCOF include surgical excision of the lesion. A 38-year-old female reported slow-growing swelling associated with the maxillary anterior region. Removal of the lesion is done by using a scalpel, and histopathological examination revealed the peripheral type of cemento-ossifying fibroma. This case report demonstrates the management of PCOF lesions with the conventional scalpel approach with the help of proper clinical examination, radiological findings, and histopathological examination, which reveals favourable outcomes in the patient regarding esthetics and improves mastication-related issues and speech.
ABSTRACT
An inflammatory hyperplasia known as a pyogenic granuloma (PG) appears as a nodular growth on the oral mucosa. The most frequent place is the gingiva, followed by the buccal mucosa, tongue, and lips. Histologically, the surface epithelium may be hyperkeratotic, have ulceration foci, or be intact. It lies on the dense connective tissue that contains a sizable amount of fully developed collagen. Most of the pregnancies result in PG of the gingiva; for this reason, the phrases "Pregnancy Tumor" and "Granuloma Gravidarum" are frequently used. It typically occurs during the second and third months of pregnancy and tends to bleed, making it challenging to masticate. Estrogen increases the vascular endothelial growth factor (VEGF) synthesis in macrophages, which is associated with PG development during pregnancy. This case describes a surgically treated case of PG in a middle-aged female with a conventional scalpel technique, giving functional and esthetic outcomes in a patient.
ABSTRACT
Nanotechnology has revolutionized dentistry by transforming how oral health care is conceptualized, delivered, and maintained. Harnessing nanomaterials and advanced clinical instruments has opened new avenues for precision and innovation across various aspects of dental care. Nanotechnology offers the potential for precise pain management, tooth restoration, and alleviating dental hypersensitivity. Nanomaterials can occlude exposed dentinal tubules, enhancing patient comfort and overall oral well-being. Orthodontic therapy is also revolutionized by nanomaterials with shape memory properties, enabling rapid and more efficient tooth movement. The development of groundbreaking products and therapeutic alternatives is supported by ongoing research efforts, enabling the formation of dental implants, fillings, and prosthetic devices that closely mimic natural tooth characteristics. Nano-delivery systems are being devised for precise drug delivery within the oral cavity, ensuring optimal therapeutic outcomes with minimal side effects. The integration of nanotechnology in dentistry represents a groundbreaking evolution beyond the conventional boundaries of oral health care, enabling the development of innovative diagnostic techniques and improved oral well-being.
ABSTRACT
Background Assessment of cancer patients' relatives' knowledge, perception, and attitude regarding cancer. To spread awareness about oral cancer in areas with a high prevalence of cancer, aid in its prevention, and accelerate the treatment to facilitate early-stage disease elimination and improve prognosis. Material and methods A cross-sectional study conducted at a hospital was done, where 23 questions were posed to the relatives of the patients admitted to the hospital. The questions were formulated to assess the knowledge of relatives regarding cancer, their perception, and their attitude toward the decision-making and treatment protocols. The questions also included information about the patient's habits and associated problems with it. A total of 400 relatives participated in the study, where all participants were adequately informed beforehand, and their written consent was taken before proceeding with the questions. All the questions were formulated in the native language that they could easily understand. Result The study found that participants had limited knowledge about the causes, treatment, prevention, and recurrence of oral cancer. Additionally, the family members were unsupportive of therapy and delayed seeking medical care. Conclusion It is crucial to raise awareness about oral cancer and inform individuals about available treatments, government programs, and counseling services to aid them in decision-making.
ABSTRACT
An eight-year-old child presented with nasal discharge, stuffiness, and whitish polypoid swelling in the left nostril with Bitot's spot. Computed tomography (CT) evaluation showed complete involvement of the left nostril and maxillary sinus. Blood investigations revealed leukocytosis, raised absolute eosinophils, increased alkaline phosphatase, and reduced vitamin A levels. Histopathological examination revealed inflammatory infiltrate with Leishman-Donovan bodies, which confirms the diagnosis of mucosal leishmaniasis (ML). In the present case, the recording of demographic data is important as the child was a migrant from the leishmaniasis-endemic area of Bihar state, India. Nasal polypoid growth was removed by endoscopic surgery, followed by a combination of allopathic and polyherbal preparation. The child responded well to these therapeutic measures, and there was no recurrence of nasal discharge, stuffiness, and crustation at six-month follow-up.
ABSTRACT
INTRODUCTION: Areca nut is deeply rooted sociocultural habit in India. Areca nut reported to be infested by fungi during the field and storage conditions. Areca nut alkaloids, nitrosamines, tobacco and aflatoxin are cytotoxic, immunotoxic to red blood cell and epithelial cell. Hence, the present study was conducted to assess the serum aflatoxin B1 (AFB1) antibody titer, percent hemolysis and transaminases in oral submucous fibrosis (OSMF) patients. MATERIALS AND METHODS: In this study, 128 participants of which 88 were suffering from OSMF. Twenty participants were areca nut habitual without OSMF (habitual control) and 20 participants without any habit (healthy control). For the detection of AFB1 antibody titer, AFB1 antigen (Sigma) A6636 from Aspergillus flavus was used. Percent hemolysis was estimated as per the procedure described by Mathuria and Verma. Serum Glutamic oxalo acetic transaminase (SGOT) and Serum Glutamic pyruvic transaminase (SGPT) were estimated by the optimized ultraviolet method using the enzyme-linked immunosorbent assay kit. RESULTS: Mean SGOT, SGPT, percent hemolysis and AFB1 antibody titer were significantly higher in participants with OSMF than the habitual and healthy controls. AFB1 antibody titer and % hemolysis in both OSMF and habitual without OSMF were showed significant correlation, i.e., increased AFB1 antibody titer with increased % hemolysis. CONCLUSIONS: A study result demonstrates that aflatoxin causes increase in serum transaminases which is indicative of liver damage in OSMF. The combined toxic effects of areca nut alkaloids, tobacco and AFB1 on red blood cell (RBC) cell wall might be responsible for increased percent hemolysis in OSMF and habitual control.
ABSTRACT
Pemphigus Vulgaris is an autoimmune disease that causes severe blistering of the skin and mucous membrane which are fragile and breaks away leaving erosions that are extremely painful. Here we report a case of a patient suffering from pemphigus vulgaris with typical oral manifestations. We have reported the effect of treatment after two consecutive recalls at an interval of 1 week where the patient got 100% relief from her previous signs and symptoms.
