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Antimicrob Agents Chemother ; 53(1): 287-91, 2009 Jan.
Article in English | MEDLINE | ID: mdl-19001116

ABSTRACT

Among 177 extended-spectrum beta-lactamase-producing Klebsiella pneumoniae isolates collected from 11 Slovenian hospitals in 2005 and 2006, 60 (34%), from eight hospitals, harbored genes for CTX-M enzymes, with bla(CTX-M-15) detected by sequencing. These 60 isolates comprised 11 pulsed-field gel electrophoresis-defined strains, with several clusters of closely related isolates. Plasmids encoding CTX-M-15 enzyme were highly transmissible.


Subject(s)
Klebsiella pneumoniae/enzymology , Klebsiella pneumoniae/genetics , beta-Lactamases/genetics , Anti-Bacterial Agents/pharmacology , Electrophoresis, Gel, Pulsed-Field , Genes, Bacterial/genetics , Genes, Bacterial/physiology , Hospitals , Klebsiella pneumoniae/drug effects , Microbial Sensitivity Tests , Slovenia
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