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1.
Cochrane Database Syst Rev ; 8: CD013260, 2020 08 25.
Article in English | MEDLINE | ID: mdl-35659470

ABSTRACT

BACKGROUND: Traumatic eye complaints account for 3% of all hospital emergency department visits. The most common traumatic injury to the eye is blunt trauma, which accounts for 30% of these visits. Blunt trauma frequently leads to traumatic iridocyclitis, thus causing anterior uveitis. Iridocyclitis frequently causes tearing, photophobia, eye pain, and vision loss. These symptoms are a result of the inflammatory processes and ciliary spasms to iris muscles and sphincter. The inflammatory process is usually managed with topical corticosteroids, while the ciliary spasm is blunted by dilating the pupils with topical mydriatic agents, an adjuvant therapy. However, the effectiveness of mydriatic agents has not been quantified in terms of reduction of ocular pain and visual acuity loss. OBJECTIVES: To evaluate the effectiveness and safety of topical mydriatics as adjunctive therapy to topical corticosteroids for traumatic iridocyclitis. SEARCH METHODS: We searched the Cochrane Central Register of Controlled Trials (CENTRAL) which contains the Cochrane Eyes and Vision Trials Register (2019, issue 6); Ovid MEDLINE; Embase.com; Cumulative Index to Nursing and Allied Health Literature (CINAHL) Plus; PubMed; ClinicalTrials.gov and the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP). We did not use any date or language restrictions in the electronic search for trials. We last searched the electronic databases on 12 June 2019. SELECTION CRITERIA: We planned to include randomized controlled trials (RCTs) that compared topical mydriatic agents in conjunction with topical corticosteroid therapy versus topical corticosteroids alone, in participants with traumatic iridocyclitis. DATA COLLECTION AND ANALYSIS: Two review authors (JH, MK) independently screened titles and abstracts, then full-text reports, against eligibility criteria. We planned to have two authors independently extract data from included studies. We resolved differences in opinion by discussion. MAIN RESULTS: There were no eligible RCTs that compared the interventions of interest in people with traumatic iridocyclitis. AUTHORS' CONCLUSIONS: We did not find any evidence from RCTs about the efficacy of topical mydriatic agents as an adjunctive therapy with topical corticosteroids for treating traumatic iridocyclitis. In the absence of these types of studies, we cannot draw any firm conclusions. Controlled trials that compare the combined use of topical mydriatic agents and corticosteroid drops against standard corticosteroid drops alone, in people with traumatic iridocyclitis are required. These may provide evidence about the efficacy and risk of topical mydriatic drops as adjuvant therapy for traumatic iridocyclitis.

2.
Ethn Health ; 25(6): 862-873, 2020 08.
Article in English | MEDLINE | ID: mdl-29506393

ABSTRACT

Chinese American women have lower rates of mammography screening compared with non-Hispanic White women. Although the extent of perceived barriers, as conceptualized by the Health Belief Model, have been shown to distinguish between currently non-adherent Chinese American women who have ever and never had a mammogram, it is less clear which types of perceived barriers differentiate them. One hundred twenty-eight Chinese American women in the New York metropolitan area who had not had a mammogram in the past year completed baseline assessments for a mammography framing intervention study. Demographics, medical access variables, and perceived barriers to mammography (lack of access, lack of need for screening, and modesty) were used to predict mammography history (ever versus never screened). Fifty-five women (43%) reported having been screened at least once. A sequential logistic regression showed that English speaking ability and having health insurance significantly predicted mammography history. However, these control variables became non-significant when the three barrier factors were included in the final model. Women who reported a greater lack of access (OR = 0.36, p < .05) and greater lack of need (OR = 0.27, p < .01) were less likely to be ever screeners. Unexpectedly, women who reported greater modesty were more likely to be ever screeners (OR = 4.78, p < .001). The results suggest that interventions for Chinese American women should identify and target specific perceived barriers with consideration of previous adherence.


Subject(s)
Asian/psychology , Early Detection of Cancer , Health Services Accessibility , Mammography/economics , Mammography/psychology , Patient Acceptance of Health Care , Breast Neoplasms/prevention & control , China/ethnology , Female , Humans , Mammography/statistics & numerical data , Middle Aged , New York
3.
Hosp Pediatr ; 9(12): 942-948, 2019 12.
Article in English | MEDLINE | ID: mdl-31676585

ABSTRACT

OBJECTIVES: Hospitalization generates increased psychological discomfort for children and their caregivers. This anxiety can affect the patient-caretaker response to the health care team and the course of treatment. We aim to evaluate the impacts of a magic therapy program, organized and facilitated by medical students, on alleviating pediatric inpatient and caregiver anxiety. METHODS: Patients aged 5 to 16 years admitted to an inpatient pediatric unit and their caregivers were eligible for inclusion. Patient-caregiver pairs were randomly assigned to a magic therapy intervention group or a control group. Anxiety was measured before and after the intervention by using validated self-report tools. The Facial Image Scale and Venham Picture Test were used to measure anxiety for young patients, the short State-Trait Anxiety Inventory and Facial Image Scale were used for older patients, and the short State-Trait Inventory was used for caregivers. A subset of the intervention group was reevaluated at 1 hour posttherapy. Health professionals were also surveyed regarding their opinions of the program. RESULTS: One hundred patients and 90 caregivers were enrolled. The patient magic group's standardized anxiety was reduced by 25% (n = 47; P < .001) posttherapy. The caregiver magic group's anxiety was reduced by 24% (n = 34; P < .001). Data suggest that anxiety reductions lasted through at least 1 hour posttherapy. Physicians (n = 9), nurses (n = 8), and pediatric residents (n = 20) supported program continuance, reported favorable impressions, and suggested patient, caregiver, and staff benefits. CONCLUSIONS: Integration of a magic therapy program into pediatric inpatient care was feasible and successful in decreasing patient and caretaker anxiety. Health care professionals support the program's continuance.


Subject(s)
Adaptation, Psychological , Anxiety/prevention & control , Anxiety/psychology , Inpatients/psychology , Magic/psychology , Adolescent , Anxiety/therapy , Caregivers/psychology , Caregivers/statistics & numerical data , Child , Child, Preschool , Female , Hospitalization/statistics & numerical data , Humans , Inpatients/statistics & numerical data , Male , Patient Satisfaction/statistics & numerical data
4.
Article in English | MEDLINE | ID: mdl-31212888

ABSTRACT

Background: The use of high-nicotine content e-cigarettes (so-called pods, such as Juul) among adolescents raises concerns about early onset of nicotine addiction. Methods: In this analysis of adolescents surveyed from April 2017-April 2018, we compare survey responses and urinary cotinine of pod vs. non-pod using past-week e-cigarette users aged 12-21. Results: More pod users categorized themselves as daily users compared to non-pod users (63.0% vs. 11.0%; p = 0.001); more pod than non-pod users had used e-cigarettes within the past day (76.2% vs. 29.6%; p = 0.001). More pod users responded affirmatively to nicotine dependence questions (21.4% vs. 7.1%; p = 0.04). Urinary cotinine levels were compared among those responding positively and negatively to dependence questions: those with positive responses had significantly higher urinary cotinine levels than those responding negatively. Conclusions: Adolescents who used pod products showed more signs of nicotine dependence than non-pod users. Pediatricians should be vigilant in identifying dependence symptoms in their patients who use e-cigarettes, particularly in those using pod devices.


Subject(s)
Cotinine/urine , Electronic Nicotine Delivery Systems/statistics & numerical data , Nicotine/urine , Tobacco Use Disorder/diagnosis , Adolescent , Adult , Child , Female , Humans , Indicators and Reagents , Male , Surveys and Questionnaires , Young Adult
5.
Pediatrics ; 143(5)2019 05.
Article in English | MEDLINE | ID: mdl-31010908

ABSTRACT

BACKGROUND: Surveys have been instrumental in describing adolescent use of tobacco, electronic cigarettes (e-cigarettes), and marijuana. However, objective biomarker data are lacking. We compared adolescent self-reported use to urinary biomarkers. METHODS: From April 2017 to April 2018, adolescents 12 to 21 years old completed an anonymous questionnaire regarding tobacco, e-cigarette, and marijuana use and provided a urine sample. Urine was analyzed for biomarkers cotinine, total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and tetrahydrocannabinolic acid (THCA). RESULTS: Of 517 participants, 2.9% reported using tobacco, 14.3% e-cigarettes, and 11.4% marijuana in the past week. Only 2% reporting no smoking had total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol levels above cutoff (14.5 pg/mL); 2% of non-e-cigarette users had cotinine above cutoff (10 ng/mL); 2% of those denying marijuana use had THCA above cutoff (10 ng/mL). Daily e-cigarette users showed significantly higher median cotinine than nondaily users (315.4 [interquartile range (IQR) 1375.9] vs 1.69 ng/mL [IQR 28.2]; P < .003). Overall, 40% who reported using nicotine-free products had cotinine >10 ng/mL. Pod users' median cotinine was significantly higher than in nonpod users (259.03 [IQR 1267.69] vs 1.61 ng/mL [IQR 16.3]; P < .003). Median THCA among daily marijuana users was higher than in nondaily users (560.1 [IQR 1248.3] vs 7.2 ng/mL [IQR 254.9]; P = .04). Sixty-one percent of those with cotinine >10 ng/mL vs 39% of those with cotinine<10 ng/mL had THCA >10 ng/mL (P < .001). CONCLUSIONS: Adolescents' self-report correlated with measured urinary biomarkers, but subjects were unaware of their nicotine exposure. More frequent e-cigarette and pod use correlated with elevated biomarkers. Co-use of tobacco, e-cigarettes, and marijuana was corroborated by higher THCA in those with higher cotinine.


Subject(s)
Electronic Nicotine Delivery Systems , Marijuana Use/urine , Self Report/standards , Tobacco Use/urine , Vaping/urine , Adolescent , Biomarkers/urine , Child , Female , Humans , Male , Marijuana Use/epidemiology , Tobacco Use/epidemiology , Vaping/epidemiology , Young Adult
6.
Health Educ Behav ; 46(4): 569-581, 2019 08.
Article in English | MEDLINE | ID: mdl-30808245

ABSTRACT

Background. The gateway behavior hypothesis posits that change in a health behavior targeted for modification may promote positive changes in other untargeted health behaviors; however, previous studies have shown inconsistent results. Aims. To examine the patterns and predictors of change in untargeted health behaviors in a large health behavior change trial. Method. Using repeated-measures latent class analysis, this study explored patterns of change in untargeted physical activity, alcohol consumption, and smoking behavior during the first year of the Women's Health Initiative dietary modification trial that targeted total fat reduction to 20% kcal and targeted increased fruit and vegetable intake. Participants were healthy postmenopausal women who were randomly assigned to either the low-fat dietary change intervention (n = 8,193) or a control (n = 12,187) arm. Results. Although there were increases in untargeted physical activity and decreases in alcohol consumption and smoking in the first year, these changes were not consistently associated with study arm. Moreover, although the results of the repeated-measures latent class analysis identified three unique subgroups of participants with similar patterns of untargeted health behaviors, none of the subgroups showed substantial change in the probability of engagement in any of the behaviors over 1 year, and the study arms had nearly identical latent class solutions. Discussion and Conclusion. These findings suggest that the dietary intervention did not act as a gateway behavior for change in the untargeted behaviors and that researchers interested in changing multiple health behaviors may need to deliberately target additional behaviors.


Subject(s)
Diet, Healthy/methods , Health Behavior , Health Promotion/methods , Aged , Diet, Fat-Restricted/methods , Diet, Healthy/psychology , Diet, Healthy/statistics & numerical data , Female , Fruit , Humans , Middle Aged , Vegetables
7.
J Matern Fetal Neonatal Med ; 32(16): 2688-2693, 2019 Aug.
Article in English | MEDLINE | ID: mdl-29526120

ABSTRACT

PURPOSE: To compare discharge breastmilk feeding rates among asymptomatic term newborns receiving 48-hour versus >48-hour antibiotics in the neonatal intensive care unit (NICU) and a cohort of well-baby nursery (WBN) newborns. MATERIALS AND METHODS: This retrospective review included asymptomatic term neonates admitted to the NICU due to maternal chorioamnionitis and a comparison group of WBN neonates between January 2012 and December 2015. Demographic, birth, feeding, and lactation consultant visit data were analyzed in univariate and multivariate models. RESULTS: Among 272 NICU neonates, 237 (87%) received 48-hour antibiotics versus 35 (13%) who received >48-hour (h) antibiotics; a cohort of 428 WBN neonates was studied for comparison. Exclusive breastmilk feeding was seen in 14% of NICU versus 35% of WBN neonates (p < .01). Among NICU newborns, 48 h versus >48 h antibiotics was not associated with altered discharge breastmilk feeding (14 versus 14%; p = .89). On multivariate logistic regression analysis among NICU subjects, older maternal age (p < .01), lower parity (p = .02), first-feed breastmilk (p < .01), and more lactation consultant visits (p = .012) were associated with increased discharge breastmilk feeding. CONCLUSIONS: NICU admission for presumed early-onset sepsis due to maternal chorioamnionitis was associated with reduced discharge breastmilk feeding in asymptomatic term neonates, but prolonged antibiotic exposure was not. We speculate that demographic factors, such as maternal age and parity, may aid in focusing lactation consultant efforts to potentially improve NICU exclusive discharge breastmilk feeding rates.


Subject(s)
Anti-Bacterial Agents/therapeutic use , Breast Feeding/statistics & numerical data , Intensive Care Units, Neonatal/statistics & numerical data , Neonatal Sepsis/prevention & control , Adult , Antibiotic Prophylaxis/methods , Case-Control Studies , Chorioamnionitis/drug therapy , Female , Humans , Infant, Newborn , Patient Discharge/statistics & numerical data , Pregnancy , Retrospective Studies
9.
Clin Pediatr (Phila) ; 57(4): 398-402, 2018 04.
Article in English | MEDLINE | ID: mdl-28877602

ABSTRACT

The therapeutic alliance between pediatricians and parents begins at the initial encounter. The manner in which pediatricians greet family members influences this relationship. This study evaluated whether parents are addressed using generic titles and investigated perceptions of parents regarding how they are addressed by medical staff. Written surveys of 137 parents of pediatric inpatients collected opinions about greetings during medical encounters. Parents were asked if they have been addressed as Mom/Dad/Mommy/Daddy during past medical encounters and which generic titles they would prefer. Using a Likert-type scale, the parents' perceptions of various salutations were assessed and compared. In this sample, 86% of parents were previously called Mom/Dad/Mommy/Daddy. Parents preferred to be addressed as Mom or Dad over other generic titles. Many disliked being addressed as Mommy/Daddy, Ma'am/Sir, or without a name, suggesting that providers should avoid the use of these salutations.


Subject(s)
Names , Parents/psychology , Patient Satisfaction/statistics & numerical data , Physician-Patient Relations , Professional-Family Relations , Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , New York , Surveys and Questionnaires/statistics & numerical data , Young Adult
11.
Ann Behav Med ; 51(4): 500-510, 2017 Aug.
Article in English | MEDLINE | ID: mdl-28194642

ABSTRACT

BACKGROUND: Optimism and cynical hostility independently predict morbidity and mortality in Women's Health Initiative (WHI) participants and are associated with current smoking. However, their association with smoking cessation in older women is unknown. PURPOSE: The purpose of this study is to test whether optimism (positive future expectations) or cynical hostility (mistrust of others) predicts smoking cessation in older women. METHODS: Self-reported smoking status was assessed at years 1, 3, and 6 after study entry for WHI baseline smokers who were not missing optimism or cynical hostility scores (n = 10,242). Questionnaires at study entry assessed optimism (Life Orientation Test-Revised) and cynical hostility (Cook-Medley, cynical hostility subscale). Generalized linear mixed models adjusted for sociodemographics, lifestyle factors, and medical and psychosocial characteristics including depressive symptoms. RESULTS: After full covariate adjustment, optimism was not related to smoking cessation. Each 1-point increase in baseline cynical hostility score was associated with 5% lower odds of cessation over 6 years (OR = 0.95, CI = 0.92-0.98, p = 0.0017). CONCLUSIONS: In aging postmenopausal women, greater cynical hostility predicts lower smoking cessation over time. Future studies should examine whether individuals with this trait may benefit from more intensive cessation resources or whether attempting to mitigate cynical hostility itself may aid smoking cessation.


Subject(s)
Hostility , Optimism/psychology , Postmenopause/psychology , Smoking Cessation/psychology , Aged , Female , Humans , Middle Aged
13.
Soc Sci Med ; 150: 23-30, 2016 Feb.
Article in English | MEDLINE | ID: mdl-26722985

ABSTRACT

RATIONALE: There are vast global disparities in the burden of cervical cancer; 85% of incident cases and 87% of deaths occur in the developing world. There is a growing body of literature asserting that women's autonomy is associated with a broad range of health outcomes. OBJECTIVE: This study examined the relationship between women's autonomy and cervical cancer screening to inform interventions in global cervical cancer care. METHODS: A generalized estimating equation approach to logistic regression was used to analyze associations between women's autonomy indicators and both cervical cancer screening knowledge and personal history in a cross sectional sample of 4049 married women in Lesotho. RESULTS: More than half of the women surveyed (65.2%) had never heard of a pap smear, and only 7.2% had ever had one. Women who participated in all types of household decision-making were 1.4 times more likely to have heard of a pap smear (estimated risk ratio = 1.4, 95% confidence interval: 1.0, 1.8) compared to women with lower participation levels (p = 0.032). CONCLUSIONS: This study extends earlier research demonstrating that women's autonomy predicts improved health outcomes, to include cervical cancer screening awareness, but not action. This finding, that augmenting women's autonomy improves cervical cancer screening awareness, adds yet another to the myriad reasons for focusing global attention on issues of gender equity.


Subject(s)
Early Detection of Cancer/psychology , Health Knowledge, Attitudes, Practice , Personal Autonomy , Uterine Cervical Neoplasms/diagnosis , Adolescent , Adult , Cross-Sectional Studies , Early Detection of Cancer/methods , Female , Humans , Lesotho , Mass Screening/methods , Middle Aged , Papanicolaou Test , Surveys and Questionnaires , Uterine Cervical Neoplasms/prevention & control
14.
J Crit Care ; 31(1): 172-7, 2016 Feb.
Article in English | MEDLINE | ID: mdl-26507641

ABSTRACT

PURPOSE: To describe educational features in palliative and end-of-life care (PEOLC) in pulmonary/critical care fellowships and identify the features associated with perceptions of trainee competence in PEOLC. METHODS: A survey of educational features in 102 training programs and the perceived skill and comfort level of trainees in 6 PEOLC domains: communication, symptom control, ethical/legal, community/institutional resources, specific syndromes, and ventilator withdrawal. We evaluated associations between perceived trainee competence/comfort in PEOLC and training program features, using regression analyses. RESULTS: Fifty-five percent of program directors (PDs) reported faculty with training in PEOLC; 30% had a written PEOLC curriculum. Neither feature was associated with trainee competence/comfort. Program directors and trainees rated bedside PEOLC teaching highly. Only 20% offered PEOLC rotations; most trainees judged these valuable. Most PDs and trainees reported that didactic teaching was insufficient in communication, although sufficient teaching of this was associated with perceived trainee competence in communication. Perceived trainee competence in managing institutional resources was rated poorly. Program directors reporting significant barriers to PEOLC education also judged trainees less competent in PEOLC. Time constraint was the greatest barrier. CONCLUSION: This survey of PEOLC education in US pulmonary/critical care fellowships identified associations between certain program features and perceived trainee skill in PEOLC. These results generate hypotheses for further study.


Subject(s)
Critical Care , Education, Medical, Graduate/methods , Palliative Care , Terminal Care , Adult , Attitude of Health Personnel , Clinical Competence , Curriculum , Education, Medical, Graduate/standards , Fellowships and Scholarships , Female , Humans , Male , Regression Analysis , United States
15.
Hosp Pediatr ; 5(12): 619-23, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26573484

ABSTRACT

OBJECTIVES: Study objectives were to compare smoking cessation rates between parents in the newborn nursery (NBN) versus the NICU and compare acceptance of referral to the New York State Smoker's Quitline (NYSSQL) between the 2 units. Secondary aims were to identify opportunities for improved smoking cessation interventions with parents of newborns. METHODS: From January through December 2013, smoking parents/caregivers of infants in the NBN and NICU (n = 226) completed a 34-item questionnaire. For those who accepted electronic referral to the NYSSQL, participation/outcome data and questionnaire data were matched. Relationships were examined using the χ(2) test of independence. RESULTS: The majority of respondents had cut back (56%) or quit (36%) prenatally. Seventy-nine percent of NBN parents accepted referred to the NYSSQL versus 53% of NICU parents; odds ratio = 3.31 (1.48-7.40; P < .01). At 7- to 8-month follow-up (n = 35): 11 of 28 (NBN) versus 0 of 7 (NICU) quit, 11 of 28 (NBN) versus 5 of 7 (NICU) cut back, 6 of 28 (NBN) versus 2 of 7 (NICU) did not quit/cut back (P = .13). Significantly more mothers (80%; 16/20) compared with fathers (46%; 6/13) quit/cut back, 20% (4/20) of mothers versus 54% (7/13) of fathers did not quit/cut back (P = .04). Exclusive formula-feeding rates were higher in this cohort of smokers surveyed than in all parents of infants admitted to the NBN/NICU for the same year (45% vs 13%). CONCLUSIONS: In this study population, parents of healthy newborns were more receptive to quitline referrals than parents of infants admitted to the NICU.


Subject(s)
Intensive Care Units, Neonatal , Nurseries, Hospital , Parents/psychology , Patient Acceptance of Health Care/psychology , Smoking Cessation/psychology , Adult , Female , Humans , Infant, Newborn , Intention , Male , Socioeconomic Factors , Surveys and Questionnaires , Young Adult
16.
Patient Educ Couns ; 98(7): 878-83, 2015 Jul.
Article in English | MEDLINE | ID: mdl-25858632

ABSTRACT

OBJECTIVES: This study examined the role of women's perceptions about the relative pros versus cons (decisional balance) of mammography in moderating Chinese American women's responses to gain- and loss-framed messages that promote mammography. METHODS: One hundred and forty-three Chinese American women who were currently nonadherent to guidelines for receiving annual screening mammograms were randomly assigned to read either a gain- or loss-framed culturally appropriate print brochure about mammography screening. Mammography screening was self-reported at a 2-month follow-up. RESULTS: Although there was not a main effect for message frame, the hypothesized interaction between message frame and decisional balance was significant, indicating that women who received a framed message that matched their decisional balance were significantly more likely to have obtained a mammogram by the follow-up than women who received a mismatched message. CONCLUSIONS: Results suggest that decisional balance, and more generally, perceptions about mammography, may be an important moderator of framing effects for mammography among Chinese American women. PRACTICE IMPLICATIONS: The match between message frame and decisional balance should be considered when attempting to encourage Chinese American women to receive mammography screening, as a match between the two may be most persuasive.


Subject(s)
Asian/psychology , Health Promotion/methods , Mammography/psychology , Mammography/statistics & numerical data , Mass Screening/psychology , Pamphlets , Patient Acceptance of Health Care/ethnology , Persuasive Communication , Adult , Asian/ethnology , Asian/statistics & numerical data , Attitude to Health/ethnology , Breast Neoplasms/diagnosis , Breast Neoplasms/ethnology , Breast Neoplasms/prevention & control , Breast Neoplasms/psychology , Early Detection of Cancer , Female , Health Behavior/ethnology , Health Knowledge, Attitudes, Practice , Healthcare Disparities , Humans , Middle Aged , Patient Acceptance of Health Care/psychology , Patient Acceptance of Health Care/statistics & numerical data , Patient Education as Topic
17.
Am J Prev Med ; 46(2): 122-35, 2014 Feb.
Article in English | MEDLINE | ID: mdl-24439345

ABSTRACT

BACKGROUND: Although epidemiologic studies have shown associations between sedentary behavior and mortality, few have focused on older women with adequate minority representation and few have controlled for both physical activity and functional status. PURPOSE: The objective of this study was to determine the relationship between sedentary time and total; cardiovascular disease (CVD); coronary heart disease (CHD); and cancer mortality in a prospective, multiethnic cohort of postmenopausal women. METHODS: The study population included 92,234 women aged 50-79 years at baseline (1993-1998) who participated in the Women's Health Initiative Observational Study through September 2010. Self-reported sedentary time was assessed by questionnaire and examined in 4 categories (≤4, >4-8, ≥8-11, >11 hours). Mortality risks were examined using Cox proportional hazard models adjusting for confounders. Models were also stratified by age, race/ethnicity, body mass index, physical activity, physical function, and chronic disease to examine possible effect modification. Analyses were conducted in 2012-2013. RESULTS: The mean follow-up period was 12 years. Compared with women who reported the least sedentary time, women reporting the highest sedentary time had increased risk of all-cause mortality in the multivariate model (HR=1.12, 95% CI=1.05, 1.21). Results comparing the highest versus lowest categories for CVD, CHD, and cancer mortality were as follows: HR=1.13, 95% CI=0.99, 1.29; HR=1.27, 95% CI=1.04, 1.55; and HR=1.21, 95% CI=1.07, 1.37, respectively. For all mortality outcomes, there were significant linear tests for trend. CONCLUSIONS: There was a linear relationship between greater amounts of sedentary time and mortality risk after controlling for multiple potential confounders.


Subject(s)
Mortality , Sedentary Behavior , Women's Health , Aged , Cohort Studies , Exercise , Female , Humans , Middle Aged , Postmenopause , Proportional Hazards Models , Prospective Studies , Sedentary Behavior/ethnology , Women's Health/ethnology
18.
JPEN J Parenter Enteral Nutr ; 38(7): 852-5, 2014 Sep.
Article in English | MEDLINE | ID: mdl-23851425

ABSTRACT

BACKGROUND: This retrospective study aimed to determine the prevalence of abnormal metabolic parameters in obese children and its correlation to the degree of obesity determined by body mass index (BMI). METHODS: In total, 101 children seen at the Pediatric Gastroenterology Obesity Clinic at Stony Brook Children's University Hospital were enrolled in the study. The degree of obesity was characterized according to the following formula: (patient's BMI/BMI at 95th percentile) × 100%, with class I obesity >100%-120%, class II obesity >120%-140%, and class III obesity >140%. A set of metabolic parameters was evaluated in these patients. Frequency distributions of all study variables were examined using the χ(2) test of independence. Mean differences among the obesity classes and continuous measures were examined using 1-way analysis of variance. RESULTS: Within our study population, we found that 80% of our obese children had a low high-density lipoprotein (HDL) cholesterol level, 58% had elevated fasting insulin levels, and 32% had an elevated alanine aminotransferase (ALT) level. Class II obese children had a 2-fold higher ALT value when compared with class I children (P = .036). Fasting insulin, ALT, HDL cholesterol, and triglyceride levels trended with class of obesity. CONCLUSION: Obese children in classes II and III are at higher risk for developing abnormal laboratory values. We recommend obese children be further classified to reflect the severity of the obesity since this has predictive significance for comorbidities. Obesity classes I, II, and III could help serve as a screening tool to help communicate risk assessment.


Subject(s)
Alanine Transaminase/blood , Body Mass Index , Cholesterol, HDL/blood , Insulin/blood , Pediatric Obesity/blood , Triglycerides/blood , Adolescent , Child , Child, Preschool , Fasting , Female , Humans , Male , Overweight , Pediatric Obesity/classification , Pediatric Obesity/metabolism , Retrospective Studies
19.
Cancer ; 119 Suppl 15: 2842-8, 2013 Aug 01.
Article in English | MEDLINE | ID: mdl-23868478

ABSTRACT

BACKGROUND: Current and pending legislation provides colorectal cancer screening reimbursement for previously uninsured populations. Colonoscopy is currently the screening method most frequently recommended by physicians for insured patients. The experience of the SCOPE (Suffolk County Preventive Endoscopy) demonstration project (Project SCOPE) at Stony Brook University Medical Center provides a model for delivering colonoscopy screening to low-income populations to meet anticipated increasing demands. METHODS: Project SCOPE, based in the Department of Preventive Medicine, featured internal collaboration with the academic medical center's large gastroenterology practice and external collaboration with the Suffolk County Department of Health Services' network of community health centers. Colonoscopies were performed by faculty gastroenterologists or supervised fellows. Measures of colonoscopy performance were compared with quality indicators and differences between faculty and supervised fellows were identified. RESULTS: During a 40-month screening period, 800 initial colonoscopies were performed. Approximately 21% of women screened were found to have adenomatous polyps compared with 36% of men. Five cancers were detected. The majority of the population screened (70%) were members of minority populations. African American individuals had a higher percentage of proximally located adenomas (78%) compared with white individuals (65%) and Hispanics (49%), based on the location of the most advanced lesion. Hispanic individuals had a 36% lower risk of adenomas compared with white individuals. Performance measures including the percentage of procedures with adequate bowel preparation, cecum reached, scope withdrawal time, and adenoma detection rate met quality benchmarks when performed by either faculty or supervised fellows. CONCLUSIONS: Project SCOPE's operational strategies demonstrated a feasible method for an academic medical center to provide high-quality screening colonoscopy for low-income populations.


Subject(s)
Colonoscopy/economics , Colonoscopy/methods , Colorectal Neoplasms/economics , Colorectal Neoplasms/prevention & control , Early Detection of Cancer/economics , Early Detection of Cancer/methods , Aged , Benchmarking , Colonoscopy/standards , Colorectal Neoplasms/diagnosis , Colorectal Neoplasms/epidemiology , Early Detection of Cancer/standards , Female , Humans , Male , Middle Aged , New York/epidemiology , Poverty , Treatment Outcome
20.
Cancer ; 119 Suppl 15: 2894-904, 2013 Aug 01.
Article in English | MEDLINE | ID: mdl-23868484

ABSTRACT

BACKGROUND: One of 5 nationally funded Centers for Disease Control and Prevention Colorectal Cancer (CRC) Screening Demonstration Programs, Project SCOPE, was conducted at an academic medical center and provided colonoscopy screening at no cost to underserved minority patients from local community health centers. METHODS: Established barriers to CRC screening (eg, financial, language, transportation) among the target population were addressed through clinical coordination of care by key project staff. The use of a clinician with a patient navigator allowed for the performance of precolonoscopy "telephone visits" instead of office visits to the gastroenterologist in virtually all patients. The clinician elicited information relevant to making screening decisions (eg, past medical and surgical history, focused review of systems, medication/supplement use, CRC screening history). The patient navigator reduced barriers, including, but not limited to, scheduling, transportation, and physical navigation of the medical center on the day of colonoscopy. RESULTS: Preprogram preparation was vital in laying groundwork for the project, yet enhancements to the program were ongoing throughout the screening period. Detailed referral forms from primary care physicians, coupled with information obtained during telephone interviews, facilitated high colonoscopy completion rates and excellent patient satisfaction. Similarly valuable was the employment of a bilingual patient navigator, who provided practical and emotional patient support. CONCLUSIONS: Academic medical centers can be efficient models for providing CRC screening to disadvantaged populations. Coordination of care by a preventive medicine department, directing the recruitment, scheduling, prescreening education, and the evaluation and preparation of target populations had an overall positive effect on CRC screening with colonoscopy among patients from a community health center.


Subject(s)
Colonoscopy/methods , Colorectal Neoplasms/diagnosis , Colorectal Neoplasms/prevention & control , Early Detection of Cancer/methods , Mass Screening/organization & administration , Academic Medical Centers/economics , Academic Medical Centers/organization & administration , Case Management/economics , Case Management/organization & administration , Colonoscopy/economics , Colorectal Neoplasms/economics , Colorectal Neoplasms/epidemiology , Early Detection of Cancer/economics , Female , Humans , Male , Mass Screening/economics , Poverty , United States
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