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Presse Med ; 34(4): 289-92, 2005 Feb 26.
Article in French | MEDLINE | ID: mdl-15798548

ABSTRACT

INTRODUCTION: Cogan's syndrome is defined by the combination of non syphilitic interstitial keratitis and inner ear dysfunction, similar to Meniere's disease. OBSERVATION: Cogan's syndrome was revealed by haemorrhagic glaireous diarrhoea in a 21 year-old woman whose medical history included Hirschsprung's disease. Cerebral MRI revealed viral-like bilateral neuritis of the eighth cranial nerve, never described in the literature before. The auditory and visual disorders regressed after treatment with corticosteroids. CONCLUSION: The early diagnosis of Cogan's syndrome permits the cure of the visual and auditory and notably inner ear symptoms with corticosteroid therapy.


Subject(s)
Cochlear Nerve , Diarrhea/etiology , Hearing Loss, Bilateral/complications , Keratitis/complications , Labyrinth Diseases/complications , Vestibulocochlear Nerve Diseases/diagnosis , Adult , Anti-Inflammatory Agents/administration & dosage , Anti-Inflammatory Agents/therapeutic use , Audiometry , Diagnosis, Differential , Female , Hearing Loss, Bilateral/drug therapy , Humans , Keratitis/diagnosis , Keratitis/drug therapy , Labyrinth Diseases/diagnosis , Labyrinth Diseases/drug therapy , Magnetic Resonance Imaging , Meniere Disease/diagnosis , Prednisone/administration & dosage , Prednisone/therapeutic use , Prognosis , Syndrome , Time Factors , Treatment Outcome , Vestibulocochlear Nerve Diseases/complications , Vestibulocochlear Nerve Diseases/drug therapy
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