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1.
Front Reprod Health ; 5: 1197931, 2023.
Article in English | MEDLINE | ID: mdl-37662068

ABSTRACT

Objectives: The purpose of this study is to report nine patients of young women who underwent a surgical treatment of an accessory and cavitated uterine mass (ACUM) in our hospital between 2014 and 2022 and review all cases described in the literature. Material and methods: The principal outcomes measured are the imaging techniques used to determine the diagnosis, the type of surgery used and the post-operative evolution of symptoms. We also report and analyse the 79 patients found in the literature since 1996 in addition to our 9 patients. Results: Surgical excision is the only long-lasting treatment. Small invasive surgery with laparoscopic access is the gold standard and most widely used (83.0%). Some new therapeutic procedures have been recently described of which ethanol sclerotherapy seems very promising. Post-operatively, 54.5% of patients have a complete relief of symptoms. MRI is the best imaging technique to identify ACUM. Finally, we refine the description of this pathology and give a more precise definition of it. Conclusion: Through our literature review and the analysis of our cases, we want to underline an important diagnostic criterion of this pathology: the fallopian tube on the homolateral side of the ACUM never communicates with the latter. It is a capital element for differential diagnosis.

2.
Prog Urol ; 2022 03 12.
Article in English | MEDLINE | ID: mdl-35292179

ABSTRACT

INTRODUCTION: Microultrasound (MicroUS) is a novel imaging modality relying on a high-frequency transducer which confers a three-fold improvement in spatial resolution as compared with conventional transrectal ultrasound. We evaluated the diagnostic value of MRI-MicroUS fusion biopsy and determined the additional benefit of employing MicroUS. METHODS: Retrospective analysis of consecutive treatment-naïve men undergoing MRI-MicroUS fusion biopsy between May 2018 and March 2019. Pre-biopsy MRI was systematically reviewed in a dedicated meeting where suspicious lesions PIRADS≥3 were registered and uploaded in the ExactVu MicroUS device. MRI and MicroUS lesions were individually marked in a PIRADS v2 scheme. The biopsy protocol included MRI-MicroUS fusion and MicroUS targeted biopsies; systematic biopsies were performed at clinician's discretion. The diagnostic value was evaluated in terms of detection rate of clinically significant prostate cancer, defined as Gleason pattern≥4 at histology. RESULTS: In all, 148 patients with a median age of 69 years (IQR 63-74) and median PSA density of 0.16ng/ml/cc (0.10-0.23) were included. Clinically significant cancer was detected in 42.5% (63/148) patients. MRI detected 89 lesions in the peripheral zone; 73% (65/89) were visible on MicroUS. Clinically significant cancer was detected in 46.1% (30/65) MRI and MicroUS visible lesions, and in 4.2% (1/24) lesions only visible on mpMRI. MicroUS additionally identified 35 suspicious lesions non-visible on MRI of which clinically significant cancer was present in 25.7% (9/35). CONCLUSION: Adding MicroUS to the conventional pathway seems to increase the detection rate of clinically significant disease in unselected men undergoing biopsy.

3.
Prog Urol ; 32(6S1): 6S26-6S32, 2022 Jun.
Article in English | MEDLINE | ID: mdl-36719643

ABSTRACT

INTRODUCTION: - Microultrasound (MicroUS) is a novel imaging modality relying on a high-frequency transducer which confers a three-fold improvement in spatial resolution as compared with conventional transrectal ultrasound. We evaluated the diagnostic value of MRI-MicroUS fusion biopsy and determined the additional benefit of employing MicroUS. METHODS: - Retrospective analysis of consecutive treatment-naïve men undergoing MRI-MicroUS fusion biopsy between May 2018 and March 2019. Pre-biopsy MRI was systematically reviewed in a dedicated meeting where suspicious lesions PIRADS ≥ 3 were registered and uploaded in the ExactVu MicroUS device. MRI and MicroUS lesions were individually marked in a PIRADS v2 scheme. The biopsy protocol included MRI-MicroUS fusion and MicroUS targeted biopsies; systematic biopsies were performed at clinician's discretion. The diagnostic value was evaluated in terms of detection rate of clinically significant prostate cancer, defined as Gleason pattern ≥ 4 at histology. RESULTS: - In all, 148 patients with a median age of 69 years (IQR 63-74) and median PSA density of 0.16 ng/ml/cc (0.10-0.23) were included. Clinically significant cancer was detected in 42.5% (63/148) patients. MRI detected 89 lesions in the peripheral zone; 73% (65/89) were visible on MicroUS. Clinically significant cancer was detected in 46.1% (30/65) MRI and MicroUS visible lesions, and in 4.2% (1/24) lesions only visible on mpMRI. MicroUS additionally identified 35 suspicious lesions non-visible on MRI of which clinically significant cancer was present in 25.7% (9/35). CONCLUSION: - Adding MicroUS to the conventional pathway seems to increase the detection rate of clinically significant disease in unselected men undergoing biopsy. © 2022 Elsevier Masson SAS. All rights reserved.


Subject(s)
Prostatic Neoplasms , Male , Humans , Middle Aged , Aged , Retrospective Studies , Prostatic Neoplasms/diagnostic imaging , Prostatic Neoplasms/pathology , Image-Guided Biopsy/methods , Magnetic Resonance Imaging/methods , Ultrasonography
4.
Diagn Interv Imaging ; 100(10): 593-605, 2019 Oct.
Article in English | MEDLINE | ID: mdl-30962168

ABSTRACT

Although mammography is currently the imaging technique of choice for screening and diagnosis, it has some limitations, especially in patients with high-density breasts. The evolution from film screen to full-field digital mammography has recently led to the development of new imaging techniques, which are less expensive and widely available. Contrast-enhanced spectral mammography (CESM) is one of them, coupling X-ray breast imaging to the intravenous administration of an iodinated contrast material. CESM provides both morphological information, similar to mammography, and functional information of tumor perfusion. In this review, the imaging technique, the specificity of interpretation of CESM compared to MRI and the currently available data are presented. The clinical performances of CESM versus those of mammography and MRI and its additional value in preoperative local assessment and screening is discussed. The potential advantages and disadvantages are mentioned and we also discuss how CESM contributes to the detection of lesions and how it can be used in daily clinical workflow.


Subject(s)
Breast Neoplasms/diagnostic imaging , Breast/diagnostic imaging , Contrast Media , Mammography/methods , Antineoplastic Agents/therapeutic use , Contraindications, Procedure , Drug Monitoring/methods , Early Detection of Cancer , Female , Humans , Image Enhancement/methods , Magnetic Resonance Imaging , Neoadjuvant Therapy , Patient Preference , Problem Solving , Radiation Dosage , Sensitivity and Specificity
5.
Transplant Proc ; 50(10): 3192-3198, 2018 Dec.
Article in English | MEDLINE | ID: mdl-30577184

ABSTRACT

BACKGROUND: The treatment of choice in end-stage renal disease is transplantation. Hemodynamic disturbances can evoke graft loss, while early ultrasound identification of vascular problems improves outcome. The aim of this study was to identify differences in postoperative complications with and without systematic intraoperative Doppler ultrasound use. METHODS: The primary outcome was the postoperative rate of complications and the secondary aim was to find a predictive resistance index cut-off value, which would show where surgical reintervention was necessary. Over a 10-year period, 108 renal transplants were performed from living donors at our institution. In group 1 (n = 67), intraoperative duplex ultrasound and intraparenchymatous resistance index measurements assessed patients, while in group 2 (n = 41), no ultrasound was performed. RESULTS: There were no intergroup differences in the overall postoperative complication rate or in benefit to graft or patient survival with Doppler use. However, significantly more vascular complications (10% vs 0%, P = .02) and more acute rejections (37% vs 10%) occurred in group 2 than in group 1. Therefore, an intraoperative cut-off value of the resistance index 0.5 was proposed to justify immediate surgical revision. CONCLUSIONS: This is the first report demonstrating benefits of systematic intraoperative Doppler ultrasound on postoperative complications in renal transplantation from living donors. Our results support surgical revision with a resistance index <0.5.


Subject(s)
Kidney Transplantation/adverse effects , Postoperative Complications/diagnosis , Ultrasonography, Doppler/methods , Vascular Diseases/diagnosis , Vascular Resistance , Adolescent , Adult , Aged , Child , Child, Preschool , Female , Humans , Kidney Failure, Chronic/surgery , Living Donors , Male , Middle Aged , Vascular Diseases/etiology , Young Adult
7.
Eur Radiol ; 26(4): 1108-15, 2016 Apr.
Article in English | MEDLINE | ID: mdl-26201293

ABSTRACT

UNLABELLED: Tubulocystic renal cell carcinoma (TC-RCC) is a recently identified renal malignancy. While approximately 100 cases of TC-RCC have been reported in the pathology literature, imaging features have not yet been clearly described. The purpose of this review is to describe the main radiologic features of this rare sub-type of RCC on ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI), based jointly on the literature and findings from a multi-institutional retrospective HIPAA-compliant review of pathology and imaging databases. Using a combination of sonographic and CT/MRI features, diagnosis of TC-RCC appeared to be strongly suggested in many cases. KEY POINTS: • Tubulocystic renal cell carcinoma is a new entity with typical imaging features • Diagnosis of tubulocystic renal cell carcinoma can be suggested preoperatively by imaging • Cystic renal lesions with high echogenicity may correspond to tubulocystic carcinoma.


Subject(s)
Carcinoma, Renal Cell/diagnosis , Kidney Neoplasms/diagnosis , Magnetic Resonance Imaging , Tomography, X-Ray Computed , Ultrasonography , Adult , Aged , Female , Humans , Kidney/diagnostic imaging , Kidney/pathology , Male , Middle Aged , Retrospective Studies
8.
Rev Med Suisse ; 10(447): 1977-8, 1980-4, 2014 Oct 22.
Article in French | MEDLINE | ID: mdl-25518207

ABSTRACT

Endometriosis is a frequent, benign, chronic disease associated with pain and/or infertility. Classically the lesions are found on the pelvic peritoneum, ovary (endometrioma), rectovaginal septum and bladder. Management of endometrioma has evolved over the last few years to individualised treatment. Indeed endometrioma cystectomy can decrease pain and the risk of recurrence but is also associated with a decrease in ovarian reserve. A multi-disciplinary team should manage recto-vaginal or bladder endometriosis. Surgical resection of these lesions must be as complete as possible and can be complex.


Subject(s)
Endometriosis/therapy , Rectal Diseases/therapy , Urinary Bladder Diseases/therapy , Vaginal Diseases/therapy , Chronic Disease , Endometriosis/complications , Endometriosis/pathology , Female , Humans , Infertility, Female/etiology , Pain/etiology , Patient Care Team/organization & administration , Rectal Diseases/complications , Rectal Diseases/pathology , Urinary Bladder Diseases/complications , Urinary Bladder Diseases/pathology , Vaginal Diseases/complications , Vaginal Diseases/pathology
10.
Rev Med Suisse ; 7(284): 505-9, 2011 Mar 02.
Article in French | MEDLINE | ID: mdl-21462521

ABSTRACT

Radiological investigations using gadolinium or intravenous iodinated contrast products are used cautiously in patients suffering from chronic kidney disease because of their risk of acute kidney injury and systemic nephrogenic fibrosis. In this article, we review several radiological alternatives that can be useful to obtain renal anatomical and/or functional information in this patient population. The basic principles, indications, and advantages and limitations of Doppler ultrasound with measurement of the resistance index, contrast-enhanced ultrasound, and a technique called BOLD-MRI (blood-oxygenation level dependent-MRI) are discussed.


Subject(s)
Kidney Diseases/complications , Kidney/pathology , Chronic Disease , Humans , Magnetic Resonance Imaging/methods , Ultrasonography, Doppler
11.
Cancer Radiother ; 15(4): 307-15, 2011 Jul.
Article in French | MEDLINE | ID: mdl-21507695

ABSTRACT

Positron emission tomography is a functional imaging technique that allows the detection of the regional metabolic rate, and is often coupled with other morphological imaging technique such as computed tomography. The rationale for its use is based on the clearly demonstrated fact that functional changes in tumor processes happen before morphological changes. Its introduction to the clinical practice added a new dimension in conventional imaging techniques. This review presents the current and proposed indications of the use of positron emission/computed tomography for prostate, bladder and testes, and the potential role of this exam in radiotherapy planning.


Subject(s)
Positron-Emission Tomography , Prostatic Neoplasms/diagnostic imaging , Testicular Neoplasms/diagnostic imaging , Tomography, X-Ray Computed , Urinary Bladder Neoplasms/diagnostic imaging , Humans , Male , Prostatic Neoplasms/radiotherapy , Radiotherapy Planning, Computer-Assisted , Testicular Neoplasms/radiotherapy , Urinary Bladder Neoplasms/radiotherapy
12.
Rev Med Suisse ; 6(268): 2010-2, 2010 Oct 27.
Article in French | MEDLINE | ID: mdl-21137460

ABSTRACT

The abscesses of the breast are puerperal or non puerperal. The Staphylococcus aureus is the most common germ. The diagnosis is based on clinical criterias and confirmed by the ultrasonography. The percutaneous ultrasonography-guided drainage must be proposed in first intent to treat. Surgical treatment is still valid with a relapsing or chronic abscess, or after the non operative processes have failed.


Subject(s)
Abscess/therapy , Breast Diseases/therapy , Drainage , Ultrasonography, Interventional , Female , Humans
13.
Curr Med Chem ; 17(23): 2492-502, 2010.
Article in English | MEDLINE | ID: mdl-20491646

ABSTRACT

Positron emission computed tomography (PET) is a functional, noninvasive method for imaging regional metabolic processes that is nowadays most often combined to morphological imaging with computed tomography (CT). Its use is based on the well-founded assumption that metabolic changes occur earlier in tumors than morphologic changes, adding another dimension to imaging. This article will review the established and investigational indications and radiopharmaceuticals for PET/CT imaging for prostate cancer, bladder cancer and testicular cancer, before presenting upcoming applications in radiation therapy.


Subject(s)
Positron-Emission Tomography/methods , Prostatic Neoplasms/pathology , Testicular Neoplasms/pathology , Urinary Bladder Neoplasms/pathology , Animals , Humans , Male , Prostatic Neoplasms/diagnostic imaging , Prostatic Neoplasms/radiotherapy , Radiopharmaceuticals , Testicular Neoplasms/diagnostic imaging , Testicular Neoplasms/radiotherapy , Urinary Bladder Neoplasms/diagnostic imaging , Urinary Bladder Neoplasms/radiotherapy
14.
Prog Urol ; 19(5): 351-2, 2009 May.
Article in French | MEDLINE | ID: mdl-19393542

ABSTRACT

Acute testicular pain is frequent in urology. If torsion of the spermatic cord and orchiepididymitis are usual, varicocele thrombosis is an unusual clinical entity we reported.


Subject(s)
Pain/etiology , Testis , Thrombosis/complications , Varicocele/complications , Adult , Humans , Male
15.
Rev Med Suisse ; 5(228): 2442-4, 2446-7, 2009 Dec 02.
Article in French | MEDLINE | ID: mdl-20088118

ABSTRACT

Diagnostic and treatment management of prostate cancer at its initial stage continues to raise important debates within the involved medical community. To establish a protocol for active surveillance, a validated option in specific conditions of localised prostate cancer management for eight years, is a unique opportunity to gather different specialists in this field. This paper presents this concept.


Subject(s)
Prostatic Neoplasms/diagnosis , Humans , Male , Neoplasm Staging , Population Surveillance , Prostatic Neoplasms/pathology
16.
Prog Urol ; 18(9): 617-9, 2008 Oct.
Article in French | MEDLINE | ID: mdl-18986636

ABSTRACT

Closed penile fractures without hematoma and without rupture of the albuginea, though frequent, are not well documented. In most cases, faced with no or few symptoms, the patient makes little case of this painful episode. These fractures are secondarily responsible for a fibrotic response of the corpus cavernosum, which bring patients later on to the clinic. Radiological investigations show the fibrotic reaction. A diagnosis is made retrospectively, based on the patient's history.


Subject(s)
Penis/injuries , Adult , Humans , Male , Rupture , Young Adult
17.
Eur Radiol ; 17(11): 2957-63, 2007 Nov.
Article in English | MEDLINE | ID: mdl-17492288

ABSTRACT

The diagnostic performance of magnetic resonance imaging (MRI) for detection of intestinal fistulas, other than perianal, in patients with known complicated inflammatory bowel conditions (CIBC) was investigated. Our study group consisted of 20 patients (12 women, mean age 43 years) with CIBC, including Crohn's disease (n=13), colonic diverticulitis (n=3), colitis after radiotherapy (n=3) and of postoperative origin (n=1). Eleven surgically proven enteral fistulas were known in ten (50%) of these patients, being of enterovesical (n=3), enterocolic (n=2), enteroenteral (n=2), rectovaginal (n=2), rectovaginovesical (n=1) and of entercutaneous (n=1) localisation. The other ten patients (50%), used as the control group, showed MR features of CIBC, although without any fistulous tract. Multiplanar T1- and T2-weighted sequences had been performed, including gadolinium-enhanced acquisition with fat saturation (1.5 T). MR findings were independently blindly and retrospectively reviewed by three radiologists for the presence and etiology of any fistula, as well as visualization and characterization of the fistulous tract. Results were compared with surgical findings (n=16) and clinical evolution (n=4). Interobserver agreement was calculated. Interobserver agreement kappa for fistula detection was 0.71. Overall sensitivity, specificity and accuracy for fistula detection were 78.6%, 75% and 77.2%, respectively. Sensitivity for fistula characterization was 80.6%, with visualization of the fistulous tract in all cases, whereby T1-weighted gadolinium-enhanced fat-saturated images were considered the most useful sequences. Gadolinium-enhanced MRI is a reliable and reproducible tool for detection of enteral fistulas secondary to inflammatory conditions.


Subject(s)
Inflammatory Bowel Diseases/complications , Inflammatory Bowel Diseases/diagnosis , Intestinal Fistula/diagnosis , Intestinal Fistula/pathology , Magnetic Resonance Imaging/instrumentation , Magnetic Resonance Imaging/methods , Adult , Aged , Female , Gadolinium/pharmacology , Humans , Image Processing, Computer-Assisted , Inflammation , Male , Middle Aged , Models, Statistical , Reproducibility of Results , Retrospective Studies
18.
Rev Med Suisse ; 1(27): 1795-801, 2005 Jul 13.
Article in French | MEDLINE | ID: mdl-16119294

ABSTRACT

Breast cancer is the most frequent cancer among women. Screening programs are able to diagnose early lesions in an infra-clinic state. Percutaneous procedures are simple to do and well tolerated by women, they provide an histological diagnosis. This way of doing may reensure rapidly, without a surgical approach, the women with benign lesions. In cases of invasive cancers, percutaneous procedures are also able to optimize the ongoing therapeutic strategy. The type of the radiological anomaly determines the technical guidage of the procedure and the type of material. Ultrasonographic guidage is used for opacities and needles of small size can be used (micro-biopsy). With microcalcifications, the guidage is made with mammographic stereotaxis, these lesions are usually complex and they need needles of big size (macrobiopsy).


Subject(s)
Breast/pathology , Biopsy, Needle/methods , Breast Diseases/diagnosis , Female , Humans , Magnetic Resonance Imaging , Ultrasonography, Mammary
19.
Rev Med Suisse ; 1(27): 1803-8, 2005 Jul 13.
Article in French | MEDLINE | ID: mdl-16119295

ABSTRACT

Current value of sonography for the characterization of focal liver lesions Incidental focal lesions are frequently discovered during sonographic exploration of the liver. Solid lesions remain often questionable, particularly in oncological or infectious patients. Doppler exploration generally doesn't help and other modalities, such as CT, MRI or even biopsy are necessary to definitively categorize the lesion. Ultrasound contrast agents associated with contrast detection ultrasound mode give the opportunity to follow the blood flow until the capillary level. Thus the dynamical behavior of blood flow in tissue is now observable with US, as it was previously with CT or MRI alone. The aim of this paper is to review the actual knowledge about the characterization of focal liver lesions with sonographic dynamic enhancement and to discuss the advantages and limitations of this particular technique.


Subject(s)
Liver Diseases/diagnostic imaging , Contrast Media , Humans , Ultrasonography
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