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Anticancer Res ; 40(7): 4115-4121, 2020 Jul.
Article in English | MEDLINE | ID: mdl-32620660

ABSTRACT

BACKGROUND/AIM: Magnetic resonance (MR) and ultrasound (US) fusion imaging (MR-US fusion) is already used to guide prostate biopsies and has been proven accurate for diagnosing cervical cancer. In this study, we aimed to evaluate the feasibility and performance of MR-US fusion for characterizing adnexal masses. PATIENTS AND METHODS: A retrospective study was conducted between 2014 and 2018 including women referred to our Gynaecological Oncology Department for characterization of an adnexal mass (n=106). Performance of MR-US fusion was evaluated in a subgroup of patients who underwent surgery (n=26). Two readers, blinded to final histology, performed and rated US findings according to the International Ovarian Tumor Analysis simple rules score, MR according to Ovarian-Adnexal Reporting Data System Magnetic score, and MR-US fusion through a tailored score. The reference outcome was the final pathology. RESULTS: MR-US fusion had a sensitivity of 100% (95%CI=80-100), specificity of 89% (95%CI=52-99), positive likelihood ratio of 9 (95%CI=1.4-57), and accuracy of 96% (95%CI=80-99). CONCLUSION: MR-US fusion is feasible for characterizing adnexal masses to predict ovarian cancer.


Subject(s)
Magnetic Resonance Imaging , Ovarian Neoplasms/diagnostic imaging , Ovary/diagnostic imaging , Ultrasonography , Adolescent , Adult , Aged , Aged, 80 and over , Feasibility Studies , Female , Humans , Middle Aged , Ovarian Neoplasms/pathology , Ovary/pathology , Single-Blind Method , Young Adult
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