ABSTRACT
Clinical and tomographic features of retinoblastoma and posterior pole inflammatory granuloma ("pseudoretinoblastoma") as well as infectious status in both conditions were assessed in 16 children (32 eyes). The data obtained allow differential diagnosis of neoplastic and inflammatory processes and further adequate treatment.
Subject(s)
Antibodies/immunology , Retina/pathology , Retinal Neoplasms/diagnosis , Retinoblastoma/diagnosis , Tomography, Optical Coherence/methods , Adolescent , Adult , Aged , Child , Child, Preschool , Diagnosis, Differential , Female , Humans , Male , Middle Aged , Retina/immunology , Retinal Neoplasms/immunology , Retinoblastoma/immunology , Young AdultABSTRACT
Presented clinical cases show significance of up-to-date diagnostic techniques (fluorescence angiography and spectral domain optical coherence tomography) in confirmation of metastatic choroidal carcinoma diagnosis in one case and in contradiction in another and appropriate treatment prescription.
Subject(s)
Carcinoma/pathology , Choroid Neoplasms , Choroid , Macular Degeneration/diagnosis , Retina/pathology , Adult , Choroid/blood supply , Choroid/pathology , Choroid Neoplasms/pathology , Choroid Neoplasms/secondary , Diagnosis, Differential , Female , Fluorescein Angiography/methods , Humans , Male , Middle Aged , Ophthalmoscopy/methods , Regional Blood Flow , Retinal Vessels/diagnostic imaging , Tomography, X-Ray Computed/methods , Visual Field Tests/methodsABSTRACT
Prognostic significant signs of early uveal melanoma were revealed in 51 patients before and 3 months after a single transpupillary thermotherapy session using spectral domain optical coherence tomography with enhanced depth imaging, that allows planning of appropriate eye-preserving treatment.
Subject(s)
Choroid Neoplasms/diagnosis , Choroid/pathology , Early Diagnosis , Hyperthermia, Induced/methods , Melanoma/diagnosis , Tomography, Optical Coherence/methods , Uveal Neoplasms/diagnosis , Adult , Aged , Aged, 80 and over , Choroid Neoplasms/therapy , Humans , Melanoma/therapy , Middle Aged , Prognosis , Pupil , Uveal Neoplasms/therapyABSTRACT
Clinical signs characteristic for early central choroidal melanoma (42 patients) and late stage age-related macula degeneration according to AREDS (47 patients) were determined in 89 patients. These signs allow to differentiate between tumor and degenerative process thus providing appropriate treatment.
Subject(s)
Choroid Neoplasms/diagnosis , Diagnostic Techniques, Ophthalmological , Macular Degeneration/diagnosis , Melanoma/diagnosis , Uveal Neoplasms/diagnosis , Aged , Choroid Neoplasms/pathology , Choroid Neoplasms/physiopathology , Diagnosis, Differential , Disease Progression , Female , Humans , Macular Degeneration/pathology , Macular Degeneration/physiopathology , Male , Melanoma/pathology , Melanoma/physiopathology , Patient Selection , Severity of Illness Index , Uveal Neoplasms/pathology , Uveal Neoplasms/physiopathologyABSTRACT
21 children with retinoblastoma (32 eyes, 36 lesions) were examined using optical coherence tomography (OCT). Pathognomonic features of initial primary exophytic, endophytic and mixed retinoblastoma were revealed OCT-control allowed to estimate combined treatment efficacy (chemotherapy, brachytherapy, transpupillary thermotherapy) and to reveal signs of latent growth. Thus revealed OCT signs of primary, residual retinoblastoma, retinal scar, zones of latent growth allow early estimation of appropriateness of combined eye-preserving treatment.
Subject(s)
Retina/pathology , Retinal Neoplasms/diagnosis , Retinal Neoplasms/therapy , Retinoblastoma/diagnosis , Retinoblastoma/therapy , Tomography, Optical Coherence/methods , Child , Child, Preschool , Humans , InfantABSTRACT
The presented review devoted to early diagnosis and combined eye-preserving treatment of small retinoblastoma emphasizes significance of using optical coherence tomography and transpupillary thermotherapy in malignant retinal tumors along with other options.
Subject(s)
Hyperthermia, Induced , Organ Sparing Treatments/methods , Retinal Neoplasms/diagnosis , Retinal Neoplasms/therapy , Retinoblastoma/diagnosis , Retinoblastoma/therapy , Tomography, Optical Coherence , Combined Modality Therapy , Early Diagnosis , HumansABSTRACT
Cases of bilateral uveal melanoma diagnosed with complex of clinical and instrumental methods including fluorescence angiography and optical coherent tomography are presented. Methods described in the article allow to diagnose the malignant ocular tumor at the early stage and to perform further eye-preserving treatment.
