Graphdiyne marries PEDOT:PSS to form high-stable heterostructure from 2-unstable components toward ultra-low detection limit of uric acid detection in sweat.

PEDOT: PSS has been used as a biomimetic uric acid (UA) sensor but suffers from unfortunate low detection limit (LOD), narrow detection range and poor stability. Herein, we get graphdiyne (GDY) marry PEDOT:PSS to create a very stable GDY@PEDOT:PSS heterostructure for a biomimetic UA sensor, which accomplishes the lowest LOD (6 nM), the widest detection range (0.03 µM-7 mM) and the longest stability (98.1% for 35 days) among the related UA sensors. The sensor was successfully used to in situ real-time detection of  UA in sweat. The enhancement mechanisms of the sensor were investigated, and results discover that C≡C of GDY and C = C of PEDOT:PSS can cross-link each other by π-π interactions, making not only the former strongly resistant against oxidation deterioration, but also causes the latter to efficiently prevent water swelling of polymer for poor conductivity, thereby leading to high stability from both components. While the stabilized heterostructure can also offer more active sites by enhanced absorption of UA via π-π interactions for highly sensitive detection of UA. This work holds great promise for a practical sweat UA sensor while providing scientific insight to design a stable and electrocatalytically active structure from two unstable components.

Tuning metal atom doped interface of electrospinning nanowires to toward fast bioelectrocatalysis.

Metal doping plays a key role in overcoming inefficient extracellular electron transfer between electrode interface and electricity-producing microorganisms. However, it is unknown whether different metals play distinctive roles in the doping process. Herein, three different metal ions (Fe, Ni and Cu) are added to the spinning precursor to obtain the corresponding electrospinning metal doped carbon nanofibers. It is found that the maximum output power of iron doped carbon nanofiber anode is 641.96 mW m-2, which is better than that of nickel doped carbon nanofiber (411.26 mW m-2) and copper doped carbon nanofiber (336.01 mW m-2), as well as 7.62 times higher than that of CNF. The results proved that due to the various number and types of active sites formed, as well as the distinction in surface morphology and structure, the electronegativity of each material is different. The different bio-abiotic interface could affect the direct contact between the anode interface and the extracellular protein of electricity producing microorganisms, which leading to a significant gap in the improvement of bioelectrocatalytic performance of different metal anode materials. This work provides a synthetic idea for designing highly efficient anode materials with directional metal modification and interface regulation.