ABSTRACT
The reaction of (S)-2,5-dihydrophenylalanine 1 with ruthenium(III) chloride yields the µ-chloro-bridged dimeric η(6)-phenylalanine ethyl ester complex 3, which can be converted into the monomeric analogue, η(6):κ(1)-phenylalanine ethyl ester complex 12, under basic conditions. Studies were carried out to determine the stability and reactivity of complexes bearing η(6)- and η(6):κ(1)-chelating phenylalanine ligands under various conditions. Reaction of 3 with ethylenediamine derivatives N-p-tosylethylenediamine or 1,4-di-N-p-tosylethylenediamine results in the formation of monomeric η(6):κ(1)-phenylalanine ethyl ester complexes 14 and 15, which could be saponified yielding complexes 16 and 17 without changing the inner coordination sphere of the metal centre. The structure of η(6):κ(1)-phenylalanine complex 17 and an N-κ(1)-phenylalanine complex 13 resulting from the reaction of 3 with an excess of pyridine were confirmed by X-ray crystallography.
Subject(s)
Cyclohexenes/chemistry , Phenylalanine/analogs & derivatives , Phenylalanine/chemistry , Ruthenium/chemistry , Chemistry/methods , Chemistry, Pharmaceutical/methods , Chlorides/chemistry , Crystallography, X-Ray/methods , Dimethyl Sulfoxide/chemistry , Drug Design , Esters , Ligands , Magnetic Resonance Spectroscopy/methods , Metals/chemistry , Molecular Conformation , Solvents/chemistryABSTRACT
The [2 + 2] photodimerization of Cd(II) 1,2-bis-(4-pyridyl)ethylene complex with a 3-D interpenetration network occurred in both the solid state and in the mixture solution of starting materials upon the irradiation of UV lamp with strong power or sunlight.
