Isolation of Yersinia enterocolitica biotype 1 A from raw meat products.

A survey has been carried out for the presence of Yersinia enterocolitioca in raw meat products. One hundred and twenty raw beef, chicken and ham samples were assayed for the presence of Yersinia enterocolitica by the 4 degrees C enrichment method after 2 weeks of incubation using phosphate buffered saline. Yersinia enterocolitica biotype 1 A non agglutinable (NAG) was isolated from a sample of beef and identified by Api 20 E System and additional biochemical tests, Lipase, beta-D-Glucosidase and Pyrazinamidase. The Author related about pathogenicity of Yersinia enterocolitica biotype 1 A that may cause symptoms similar to that caused by virulent biotypes. The presence of Yersinia enterocolitica in raw meat products represents a health risk for consumers therefore was suggested to yersiniosis control and further surveillance studies on epidemiology of such emerging pathogens.

Treatment of an extensive superficial basal cell carcinoma of the face with imiquimod 5% cream.

The efficacy and safety of imiquimod, an immune-response modifier approved for the treatment of anogenital warts that has antiviral and antitumor activity, in the management of an extensive superficial basal cell carcinoma (sBCC) of the face as an alternative to surgical treatment was evaluated in a 75-year-old male with a 4-year history of a progressively enlarging lesion located on the right temporal region. Imiquimod 5% cream was applied daily until clinical resolution. Histopathological confirmation of clinical diagnosis and of tumor clearance were performed before starting treatment and at the end of treatment, respectively. Moreover, monthly post-treatment follow-up visits were planned. At physical examination, an ovalar, erythematous and slightly infiltrated plaque of 5 x 4 cm in size (approximately 20 cm2), partly eroded and crusted, with a sharp, raised, pearly edge, was evident on the right temporal region of the patient. Histopathological examination of a biopsy specimen showed the typical features of sBCC. Imiquimod 5% cream applied daily for 5 months produced complete clinical and histological clearance. No adverse events but considerable irritation were reported during treatment and no relapses were clinically observed at the 6-month follow-up visit. Our findings confirm current reports from the literature showing imiquimod 5% cream to be an effective treatment for sBCC that is especially valuable in avoiding disfigurement in cases of single large lesions located on the face or in those patients who may not be surgical candidates.

[Triazolam in the treatment of presurgical patients]. / Il triazolam nel trattamento di pazienti prechirurgici.

The therapeutic action of Triazolam has been assessed against a placebo by administering the two substances on a double blind basis the evening prior to surgery. The results show that Triazolam was significantly better than the placebo as regards induction time and the duration and quality of sleep. There were few unimportant side-effects.

[Papillo-sphincterotomy in the treatment of lithiasis of the principal bile duct and of non-neoplastic stenosis of the papilla]. / La papillosfinterotomia nel trattamento della litiasi della VBP e delle stenosi non neoplastiche della papilla.

Personal experience acquired in a series of 130 papillo-sphincterotomies carried out over a five-year period for the treatment of lithiasis of the VBP and benign stenosis of the papilla is reported. An account is given of the literature data showing that his method, which is comparable with biliodigestive anastomosis techniques, is safe and reliable. Attention is also drawn to its undoubted advantages in the prevention of some serious late complications.