Cerebrovascular disease is associated with an increased disease severity in patients with Coronavirus Disease 2019 (COVID-19): A pooled analysis of published literature.

INTRODUCTION: There is an urgent need to identify patients at high risk during the ongoing coronavirus disease (COVID-19) pandemic. Whether a history of stroke is associated with increased severity of disease or mortality is unknown. METHOD: We pooled studies from published literature to assess the association of a history of stroke with outcomes in patients with COVID-19. RESULTS: A pooled analysis of 4 studies showed a ∼2.5-fold increase in odds of severe COVID-19. While a trend was observed, there was no statistically significant association of stroke with mortality in patients with COVID-19 infection. DISCUSSION: Our findings are limited by a small number of studies and sample size. CONCLUSION: There is a ∼2.5-fold increase in odds of severe COVID-19 illness with a history of cerebrovascular disease.

Spanish Translation of the Anatomical Quality Assurance (AQUA) Checklist: new guidelines for reporting in original anatomical studies

Clear reporting of original studies is an integral part of evidence-based principles, which the basic sciences, including anatomy, have only recently begun to adapt to. Evidence-based anatomy (EBA), is a developing field of anatomical research which employs evidence-based methods such as meta-analyses, systematic reviews, and high-quality original studies. However, there is a lack of standardized reporting checklist within anatomical research, and the Anatomical Quality Assurance (AQUA) Checklist was developed to account for this deficit. The AQUA Checklist serves to guide authors in clear reporting of original anatomical studies and is endorsed by the Federative International Committee for Scientific Publications (FICSP). To assure high quality, comprehensive and unambiguous description of methodology and results, the checklist consists of 29 reporting items that should be addressed by authors of original anatomical studies. The AQUA Checklist has been translated into the Spanish language to remove any language barriers and to allow utilization and reproducibility of Spanish anatomical research. Conforming to the reporting items of the AQUA Checklist will help elevate the standards of future original anatomical research and raise the quality of anatomical studies published in Spanish journals

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