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2.
Arch Inst Cardiol Mex ; 58(4): 333-7, 1988.
Article in Spanish | MEDLINE | ID: mdl-3190368

ABSTRACT

To make operative two medical computerized programs, one dedicated to the cardiological clinical record (PAC) and the other to permanent cardiac stimulation (PGP), we codified about 4000 terms concerning the general medical field and particularly the cardiological area. The importance of standardization of the medico-cardiological language is emphasized, specially in relation to the systematization of the information, necessary to work with computerized systems.


Subject(s)
Cardiology/methods , Medical Informatics Computing , Medical Records , Pacemaker, Artificial , Software , Humans
3.
Arch Inst Cardiol Mex ; 56(3): 219-23, 1986.
Article in Spanish | MEDLINE | ID: mdl-2944491

ABSTRACT

We studied sixteen patients (pts), seven men and nine women (mean age 35 years) with sustained tachyarrhythmias, for acute therapeutic trial with mexiletine (3 mg/kg IV). The arrhythmias were: ventricular tachyarrhythmia in eight pts supra-ventricular tachycardia (SVT) in eight pts, seven due to abnormal tracts (43%) and one to nodal reentry. After mexiletine administration, the sinusal cycle length was reduced in 12.7% (P less than 0.05) and the H-V interval decreased 6.1% (P less than 0.05). The nodal conduction (A-H) didn't show any substantial change, neither the atrial nor the ventricular refractory periods (RP). In two pts with complex premature ventricular beats it was not possible to induce the ventricular tachycardia(VT) six had sustained VT. After mexiletine administration, three of them (37.5%) showed self limited VT with a greater R-R cycle. Another case was complicated by ventricular fibrillation, In the pts with SVT, the retrograde RP of the abnormal tracts shortened in 27% (P less than 0.05), while the antegrade was not modified. Mexiletine showed to be efficient for the VT treatment. Its efficacy was very limited in pts with SVT. There was no evidence of any deleterious effect over the His-Purkinje conduction.


Subject(s)
Heart Conduction System/drug effects , Mexiletine/therapeutic use , Propylamines/therapeutic use , Tachycardia/drug therapy , Adolescent , Adult , Child , Drug Evaluation , Electrocardiography , Female , Humans , Male , Middle Aged , Tachycardia/physiopathology
5.
Int J Cardiol ; 9(1): 75-80, 1985 Sep.
Article in English | MEDLINE | ID: mdl-4044067

ABSTRACT

We attempted to relate admission rate for acute myocardial infarction with some meteorological variables in a region having a temperate climate. We used 2830 consecutive episodes collected over a 2-year (1979-1980) period. The temperatures, atmospheric pressure, relative humidity, front passage, rain and snow and foehn wind have been associated in the past with acute myocardial infarction. No significant association with any of them was found in our study, nor any correlation over the time between admission rates in six different Coronary Care Units (at the time the only ones active in the area) which participated in the study.


Subject(s)
Meteorological Concepts , Myocardial Infarction/epidemiology , Atmospheric Pressure , Cold Temperature , Hot Temperature , Humans , Humidity , Italy , Rain , Seasons , Snow , Wind
6.
G Ital Cardiol ; 14(5): 352-6, 1984 May.
Article in Italian | MEDLINE | ID: mdl-6468816

ABSTRACT

We have compared the efficacy of Propafenon and Mexiletine in 12 subjects (7 males and 5 females, age range of 22-61 year) affected by chronic ventricular extrasystolic beats. Propafenon and Mexiletine were orally administered in doses of 900 mg/day and 600 mg/day respectively in a single blind, cross-over fashion. Our results show that: Propafenon is better tolerated; Propafenon has caused a statistically significant reduction of the total number of ventricular ectopic beats/24 hours; the efficacy of Propafenon has been greater than that of Mexiletine (66% and 25% respectively); with both drugs, in 2 cases, there was an increase of the total number of ventricular ectopic beats/24 hours; Propafenon has induced clear-cut electrocardiogram changes (statistically significant lengthening of P-Q and Q-T intervals).


Subject(s)
Anti-Arrhythmia Agents/therapeutic use , Arrhythmias, Cardiac/drug therapy , Mexiletine/therapeutic use , Propiophenones/therapeutic use , Propylamines/therapeutic use , Adult , Drug Evaluation , Electrocardiography/methods , Female , Humans , Male , Middle Aged , Propafenone
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