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1.
Appl Opt ; 62(7): B195-B201, 2023 Mar 01.
Article in English | MEDLINE | ID: mdl-37132907

ABSTRACT

In thin film deposition processes, the lower limit of the deposition temperature is determined by the used coating technology and the duration of the coating process and is usually higher than room temperature. Hence, the processing of thermally sensitive materials and the adjustability of thin film morphology are limited. In consequence, for factual low-temperature deposition processes, an active cooling of the substrate is required. The effect of low substrate temperature on thin film properties during ion beam sputtering was investigated. The S i O 2 and T a 2 O 5 films grown at 0°C show a trend of lower optical losses and higher laser induced damage threshold (LIDT) compared to 100°C.

2.
Adv Exp Med Biol ; 1395: 347-350, 2022.
Article in English | MEDLINE | ID: mdl-36527660

ABSTRACT

Tissue oxygen saturation (StO2) is a crucial factor in the aetiology of pressure injury (PI), since hypoxia leads to necrotization. Pressure on the tissue occludes blood circulation and reduces the StO2, resulting in hypoxia. PI causes severe suffering, heals slowly and is expensive to treat. Hence it is important to prevent PI by detecting hypoxia, e.g., by near-infrared spectroscopy (NIRS) monitoring of StO2. For this, the NIRS device has to be wearable for a long time and it is crucial that it provokes no pressure itself. An integration of optical fibres into a textile achieves this. The aim was to investigate the feasibility of such a textile NIRS device.Knots and loops were tested as textile light emitters (LEs) or detectors (LDs) on a phantom. The light coupling efficiency of the LEs and LDs was investigated.Results show that knots perform similarly to loops. More loops per fibre increase efficiency both in LEs and in LDs. The best trade-off is at 3 loops. LEs are slightly more efficient than LDs, with an average attenuation from baseline of about -2 dB for loops of 0.5 mm diameter. Adding fibres multiplies the signal by the number of fibres. Inclusions mimicking hypoxia in phantoms were successfully identified. In-vivo arm occlusion tests showed the expected decrease in StO2. This shows feasibility of optical fibres in a textile to prevent PI.


Subject(s)
Optical Fibers , Oxygen , Humans , Polymers , Feasibility Studies , Oxygen Saturation , Textiles , Hypoxia , Oxygen Consumption
3.
Adv Exp Med Biol ; 1395: 411-416, 2022.
Article in English | MEDLINE | ID: mdl-36527671

ABSTRACT

The present work aims to develop a wearable, textile-integrated NIRS-based tissue oxygen saturation (StO2) monitor for alerting mobility-restricted individuals - such as paraplegics - of critical tissue oxygen de-saturation in the regions such as the sacrum and the ischial tuberosity; these regions are proven to be extremely susceptible to the development of pressure injuries (PI).Using a combination of numerical methods including finite element analysis, image reconstruction, stochastic gradient descent with momentum (SGDm) and genetic algorithms, a methodology was developed to define the optimal combination of wavelengths and source-detector geometry needed for measuring the StO2 in tissue up to depths of 3 cm. The sensor design was optimised to account for physiologically relevant adipose tissue thicknesses (ATT) between 1 mm and 5 mm. The approach assumes only a priori knowledge of the optical properties of each of the three tissue layers used in the model (skin, fat, muscle) based on the absorption and scattering coefficients of four chromophores (O2Hb, HHb, H2O and lipid).The results show that the selected wavelengths as well as the source-detector geometries and number of sources and detectors depend on ATT and the degree and volume of the hypoxic regions. As a result of a genetic algorithm used to combine the various optimised designs into a single sensor layout, a group of four wavelengths was chosen, coinciding with the four chromophores and agreeing very well with literature. The optimised number of source points and detector points and their geometry resulted in good reconstruction of the StO2 across a wide range of layer geometries.


Subject(s)
Oxygen Saturation , Spectroscopy, Near-Infrared , Humans , Spectroscopy, Near-Infrared/methods , Oxygen , Oxygen Consumption/physiology , Hypoxia
4.
Phys Rev Lett ; 111(11): 114102, 2013 Sep 13.
Article in English | MEDLINE | ID: mdl-24074090

ABSTRACT

In open chaotic systems the number of long-lived resonance states obeys a fractal Weyl law, which depends on the fractal dimension of the chaotic saddle. We study the generic case of a mixed phase space with regular and chaotic dynamics. We find a hierarchy of fractal Weyl laws, one for each region of the hierarchical decomposition of the chaotic phase-space component. This is based on our observation of hierarchical resonance states localizing on these regions. Numerically this is verified for the standard map and a hierarchical model system.

5.
Phys Rev Lett ; 84(24): 5457-61, 2000 Jun 12.
Article in English | MEDLINE | ID: mdl-10990969

ABSTRACT

We present two experiments testing the hypothesis of noncontextual hidden variables. The first one is based on observation of two-photon pseudo-Greenberger-Horne-Zeilinger correlations, with two of the originally three particles mimicked by the polarization degree of freedom and the spatial degree of freedom of a single photon. The second one, a single-photon experiment, utilizes the same trick to emulate two particle correlations, and is an "event ready" test of a Bell-like inequality, derived from the noncontextuality assumption. Modulo fair sampling, the data falsify noncontextual hidden variables.

7.
Phys Rev A ; 53(3): R1209-R1212, 1996 Mar.
Article in English | MEDLINE | ID: mdl-9913093
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