Indirect Monitoring of Frequencies of a Multiple Span Bridge Using Data Collected from an Instrumented Train: A Field Case Study.

In this paper, a field study is carried out to monitor the natural frequencies of Malahide viaduct bridge which is located in the north of Dublin. The bridge includes a series of simply supported spans, two of which collapsed in 2009 and were replaced. The replaced spans are stiffer than most of the others and these differences resulted in higher natural frequencies. An indirect bridge monitoring approach is employed in which acceleration responses from an instrumented train are used to estimate the natural frequencies of each span of the viaduct showing the locations of the two replaced spans with higher stiffness. For the indirect approach, an Ensemble Empirical Mode Decomposition (EEMD)-based Hilbert Huang Transform (HHT) technique is employed to identify the natural frequency of each span. This is carried out by analysing the Instantaneous Frequencies (IFs) from the calculated intrinsic mode functions. The average of the IFs calculated using 41 runs of the instrumented train (with varying carriage mass and speed for each run) are used to estimate the natural frequencies. To assess the feasibility of the indirect approach, a bespoke set of direct measurements was taken using accelerometers attached successively on each span of the viaduct. The free and forced vibrations from each span are used to estimate the first natural frequencies. The frequencies obtained from drive-by measurements are compared to those from direct measurements which confirms the effectiveness of indirect approaches. In addition, the instantaneous amplitudes of the drive-by signals are used to indicate the location of the stiffer spans. Finally, the accuracy and robustness of the indirect approaches for monitoring of multi span bridges are discussed.

Psoriasis and Metabolic Syndrome--scientific evidence and therapeutic implications.

Psoriasis is a chronic inflammatory disease, predominantly affecting the skin, being included in the group of Immune Mediated Inflammatory Diseases. Growing evidence from the last 10 years suggests that several systemic conditions like metabolic syndrome, cardiovascular disease, diabetes, psychological disorders or inflammatory bowel disease are prevalent in psoriasis patients. The linker might be the chronic secretion of pro-inflammatory cytokines. In this current review, the scientific evidence that explains the relationship between psoriasis and the metabolic syndrome in particular will be addressed, as the metabolic syndrome comprises a group of risk factors for cardiovascular disease, thus offering an overall picture of the systemic involvement in psoriasis. An integrated approach, with an early detection and treatment of the components of the metabolic syndrome, are important steps in psoriasis management. Attention should be paid on influence of psoriasis treatment upon comorbidities and vice-versa.

Malignant melanomas on head/neck and foot: differences in time and latitudinal trends in Norway.

BACKGROUND: Cutaneous malignant melanoma (CMM) incidence continues to increase in many parts of the world. Solar ultraviolet (UV) radiation is the main environmental risk factor for CMM. Different body locations are subjected to different doses and exposure patterns of solar UV. Time and latitudinal trends of CMMs on shielded and exposed skin give valuable information about the aetiology of these cancers. In this study, we have compared the time and latitudinal trends of CMM incidence on skin areas which are chronically (head and neck) and rarely (foot) exposed to UV radiation, to gain more information about the relationship between sun doses, exposure patterns and melanomagenesis. METHODS: We have analysed epidemiological data from the Cancer Registry of Norway, for foot and head and neck CMM for two time periods: 1966-1986 and 1987-2007. RESULTS: Cutaneous malignant melanoma incidence rate on head and neck has increased with time, while incidence rates of foot CMM have remained almost constant with time in Norway. There is a large north-south gradient in incidence rates of CMM on head and neck in Norway, while there is almost no north-south gradient for CMM incidence on foot. CONCLUSIONS: Comparisons of time trends and latitudinal trends of the incidence rates of CMM on head/neck and on foot indicate that solar radiation plays a role in the induction of the former CMM but probably not for the latter.

Comparison of the time and latitude trends of melanoma incidence in anorectal region and perianal skin with those of cutaneous malignant melanoma in Norway.

BACKGROUND: Melanoma incidence is increasing in many parts of the world. The main environmental risk factor is exposure to solar radiation. However, melanomas may arise also on non-sun-exposed areas (uveal and mucosal melanomas) and little is known about a possible relationship between sun exposure and melanoma on such locations. OBJECTIVES: We have compared the time and latitude trends of melanoma incidence in the anorectal region and perianal skin (non-sun-exposed sites) with those of cutaneous malignant melanoma (CMM) (sun-exposed skin) to gain more information about the relationship between sun exposure and melanoma on such sites. METHODS: We analysed epidemiological data from the Cancer Registry of Norway for melanomas of the anorectal mucosa, perianal skin and overall CMM for the time period 1966-2007. RESULTS: We found that melanoma incidence on these shielded sites tends to decrease or remain constant over a period during which the CMM rates increase. This is true both in the North and in the South regions of Norway. Comparison of latitudinal trends of the incidence rates of CMM and melanoma on these shielded sites shows that there is no latitude gradient for melanoma of the anorectal mucosa and perianal skin, whereas there is a strong one for CMM. CONCLUSIONS: The time and latitudinal trends are likely to support the assumption that melanomas on these shielded sites are not generated by ultraviolet radiation. Possible causes and significances of these trends are discussed.

[The clinico-epidemiological aspects of tuberculosis occurring in medical personnel in pneumophthisiology units in Bucharest (1992-1996)]. / Aspecte clinico-epidemiologice ale tuberculozei survenite la personalul medical din unitatile de pneumoftiziologie din Bucuresti (1992-1996).

The authors studied 38 TB cases diagnosed between 1992 and 1996 among the 1092 employees (medical and nonmedical) of the pneumophthisiology departments in Bucharest (hospitals and ambulatory units). Most cases had pulmonary involvement (76.3%), 85.7% were bacteriologically tested for bK. Among them, 66.7% were confirmed. The therapeutic results evaluated after 1 year, showed just 1 failure. The medium annual risk of tuberculosis at the PF personnel is corresponding to an incidence of 700/100,000 (6.36 times higher than TB incidence in general population). This conclusions calls for emergency measures for protecting and compensating this personnel.