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1.
Cir. pediátr ; 15(3): 118-121, jul. 2002.
Article in Es | IBECS | ID: ibc-14435

ABSTRACT

En las hidronefrosis congénitas obstructivas, el valor de la Función renal diferencial (FRD) es esencial para establecer un pronóstico o determinar la necesidad de tratamiento quirúrgico. El método más fiable para medir este parámetro es el estudio isotópico con DMSA. El MAG-3 se emplea fundamentalmente para estudiar la eliminación renal aunque en los minutos 1-3 también mide la FRD. Objetivo: Comparar los valores de la FRD obtenidos mediante DMSA y MAG-3 en uropatías congénitas unilaterales. Material y metodos: Se revisan 138 estudios isotópicos de niños entre 0 y 9 años, en los últimos 3 años: 67 casos de uropatía obstructiva unilateral (estenosis pieloureteral y megauréter), y 71 con uropatía no obstructiva unilateral (reflujo vesicoureteral, hipoplasia renal y duplicidad). En todos ellos se realizaron tests pareados con DMSA y MAG3 protocolizado. Ambas series se dividieron en 4 grupos: 1) FRD 50 por ciento. Se calculó, el coeficiente de correlación entre las medidas de la FRD obtenidas por DMSA y MAG-3, y comparación de medias para muestras apareadas empleando el test de Student. Resultados: Se observa una fuerte correlación lineal de la FRD obtenida con ambos métodos, en la serie obstructiva es de 0,96 (P < 0,01) y en la serie no-obstructiva de 0,92 (P < 0,01).Conclusiones: La FRD medidas con DMSA y MAG-3 tienen una alta correlación en la uropatías congénitas unilaterales, por lo tanto en las obstructivas; la FRD y el patrón de eliminación pueden estudiarse de forma fiable y segura con MAG-3 protocolizado, siendo innecesario el estudio complementario con DMSA, evitando radiación adicional al paciente (AU)


Subject(s)
Child, Preschool , Child , Male , Infant , Female , Humans , Kidney Diseases , Radiopharmaceuticals , Technetium Tc 99m Mertiatide , Severity of Illness Index , Technetium Tc 99m Dimercaptosuccinic Acid , Kidney Function Tests
2.
Cir Pediatr ; 15(3): 118-21, 2002 Jul.
Article in Spanish | MEDLINE | ID: mdl-12601986

ABSTRACT

UNLABELLED: In congenital obstructed hydronephrosis, the assessment of the differential renal function (DRF) is essential to provide a prognosis or to determine surgical treatment. The most reliable method to measure the differential renal function is the isotopic study with DMSA. The MAG-3 is employed to evaluation renal elimination, although in the minutes 1-3 it also measures the differential renal function. OBJECTIVE: We compared the estimation of differential renal function by 99Tc-dimercapto-succinic acid (DMSA) and 99Tc-mercaptoacetyltriglycyne (MAG-3) methods in congenital unilateral uropathies. MATERIALS AND METHODS: We reviewed the results of 138 isotopic studies of children (age range: 0-9 years) with congenital unilateral uropathies: 67 cases were obstructed and 71 non-obstructed. In all of them were carried out match tests pairs with DMSA and MAG-3. Both series were divided into 4 groups: 1) DRF < 40%, 2) DRF 40-45%, 3) DRF 46-50% and 4) DRF > 50%. The measurement differential renal function correlation by DMSA and MAG-3 were analysed. RESULTS: The coefficient of correlation was 0.96 (P < 0.01) in obstructed unilateral uropathy and 0.92 (P < 0.01) in non-obstructed serie. CONCLUSIONS: The differential renal function measured with DMSA and MAG-3 has a close correlation in congenital unilateral uropathies. Therefore in obstructed types, differential renal function and half-time elimination can be reliable and sure studied with MAG-3, being unnecessary DMSA test, avoiding additional radiation to the children.


Subject(s)
Kidney Diseases , Radiopharmaceuticals , Technetium Tc 99m Dimercaptosuccinic Acid , Technetium Tc 99m Mertiatide , Child , Child, Preschool , Female , Humans , Infant , Kidney Diseases/congenital , Kidney Diseases/diagnosis , Kidney Diseases/physiopathology , Kidney Function Tests , Male , Severity of Illness Index
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