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1.
Phys Rev Lett ; 109(7): 070801, 2012 Aug 17.
Article in English | MEDLINE | ID: mdl-23006352

ABSTRACT

We report the measurement of the time of flight of ∼17 GeV ν(µ) on the CNGS baseline (732 km) with the Large Volume Detector (LVD) at the Gran Sasso Laboratory. The CERN-SPS accelerator has been operated from May 10th to May 24th 2012, with a tightly bunched-beam structure to allow the velocity of neutrinos to be accurately measured on an event-by-event basis. LVD has detected 48 neutrino events, associated with the beam, with a high absolute time accuracy. These events allow us to establish the following limit on the difference between the neutrino speed and the light velocity: -3.8 × 10(-6) < (v(ν)-c)/c < 3.1 × 10(-6) (at 99% C.L.). This value is an order of magnitude lower than previous direct measurements.

2.
Vet Hum Toxicol ; 39(2): 79-83, 1997 Apr.
Article in English | MEDLINE | ID: mdl-9080631

ABSTRACT

Groups of 20 trout (Oncorynchus mykiss) were exposed for 3-w periods to different subacute oral doses of Cl2Cd (0.01, 0.025 or 0.05 microgram Cd/mL). Cadmium toxicity and accumulation were studied in kidney, liver, gills, muscle and brain weekly. Cadmium determination was carried out using atomic absorption spectrocopy (AAS) with graphite furnace. After 21 d exposure, cadmium concentrations increased significantly. In all tissues studied except muscle and brain. Cadmium storage presented the following sequence: kidney > liver > gills. At the beginning, cadmium accumulation was linearly dose dependent (r = 0.999). Then, at the highest dose (0.05 microgram Cd/mL) accumulation increased rapidly during the second week of exposure until equilibrium was reached. In contrast, liver did not accumulate cadmium selectively, suggesting that liver is able to eliminate cadmium, perhaps through metallothionein formation. Cadmium levels in gills were higher than controls (P < 0.05) and showed signs of equilibrium after the first week. According to organ weight/body weight ratios, there was similar accumulation behavior. Liver and kidney ratios increased dose dependently, but gills and brain did not have significant differences.


Subject(s)
Cadmium/pharmacokinetics , Drug Residues/pharmacokinetics , Oncorhynchus mykiss/metabolism , Water Pollutants, Chemical/pharmacokinetics , Absorption , Animals , Brain/drug effects , Brain/metabolism , Cadmium/administration & dosage , Cadmium/toxicity , Dose-Response Relationship, Drug , Drug Residues/toxicity , Female , Fresh Water/analysis , Gills/drug effects , Gills/metabolism , Hydrogen-Ion Concentration , Kidney/drug effects , Kidney/metabolism , Liver/drug effects , Liver/metabolism , Male , Muscles/drug effects , Muscles/metabolism , Quality Control , Random Allocation , Spain , Spectrophotometry, Atomic , Tissue Distribution , Water Pollutants, Chemical/toxicity
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