ABSTRACT
We presented an experience of treatment of 225 patients with non-epithelial tumors of upper gastrointestinal tract. Complicated disease's course was observed in 24% of cases. Tactical approaches are discussed depending on localization, dimensions and nature of tumor growth. Also indications for minimally invasive operations are defined. It was operated 102 (45.3%) of above-mentioned patients. Conventional surgical interventions were performed in 49 (48.0%) cases, laparoscopic operations - in 11 (10.8%) observations, endoscopic techniques using flexible endoscope - in 42 (41.2%) patients. One hundred and twenty-three (54.7%) patients were under dynamic observation. Technical features of the performed operations are described in the article. Complications were diagnosed in 8 patients including intraoperative in 3 cases and postoperative in 5 cases. Postoperative mortality was 2.0% (2 of 102 died). Overall mortality was 1.3% (3 of 225 patients died). Gastrointestinal stromal tumor (38) and leiomyoma (29) were the most frequent findings among removed tumors.
Subject(s)
Diagnostic Techniques, Digestive System , Gastrointestinal Neoplasms/diagnosis , Gastrointestinal Neoplasms/surgery , Gastrointestinal Stromal Tumors/diagnosis , Gastrointestinal Stromal Tumors/surgery , Leiomyoma/diagnosis , Leiomyoma/surgery , Adolescent , Adult , Aged , Aged, 80 and over , Endoscopy, Gastrointestinal/methods , Endosonography/methods , Female , Follow-Up Studies , Humans , Male , Middle Aged , Retrospective Studies , Time Factors , Tomography, X-Ray Computed/methods , Treatment Outcome , Upper Gastrointestinal Tract , Young AdultABSTRACT
A sensitive double antibody radioimmunoassay has been used to measure Alpha-fetoprotein in the serum of healthy subjects, pregnant women and patients with a variety of malignant diseases including leukemia and melanoma. Elevated serum Alpha-fetoprotein levels were found in 2 of 35 patients with leukemia, 2 of 10 with melanoma. All the pregnant women studied had raised levels.