ABSTRACT
INTRODUCTION: Recommendations regarding the application of primary autologous bone grafting in the surgical treatment of comminuted diaphyseal forearm fractures are conflicting. Some recent studies suggested that there is no difference in the union rate between simple and comminuted forearm fractures and that the use of bone grafting in the treatment of these fractures is therefore not necessary. Our hypothesis was that among comminuted forearm fractures there is a small group of fractures with a very large extent of comminution that heal with a significantly lower union rate and a prolonged time to union compared with other fractures. We believe that in these fractures bone grafting could help to reduce the time to union and further decrease the rate of nonunion. MATERIALS AND METHODS: We reviewed the results of the treatment of 214 consecutive patients who sustained 319 diaphyseal fractures of forearm bones. To prove our hypothesis, union rate and time to union in fractures with different extents of comminution were compared. All fractures were treated by open reduction and internal fixation with plates without the use of bone grafting. In addition, the study evaluated other factors that could influence the union rate and time to union in observed fractures. RESULTS: Separate analysis of union rate and time to union in fracture groups with different extents of comminution confirmed our hypothesis only partially. Although we proved that fractures with bone loss greater than two-thirds of the diameter of the diaphysis had a significantly prolonged time to union, we could not demonstrate a significant difference in the union rate between groups. Based on these findings, we believe that primary autologous bone grafting of comminuted diaphyseal forearm fractures is not necessary in most cases. If used, its application should be reserved only for fractures where the bone loss exceeds two-thirds of the diameter of the diaphysis. Such fractures are rare; in our study, they accounted for only 5% of all fractures. CONCLUSION: The most important factors found to influence the union rate and time to union were stability of fixation and type of plate used for fixation.
Subject(s)
Bone Transplantation/methods , Fracture Fixation, Internal/methods , Fractures, Comminuted/surgery , Ulna Fractures/surgery , Adult , Bone Plates , Female , Follow-Up Studies , Fracture Fixation, Internal/instrumentation , Fracture Healing/physiology , Fractures, Comminuted/diagnostic imaging , Humans , Injury Severity Score , Logistic Models , Male , Middle Aged , Multivariate Analysis , Predictive Value of Tests , Radiography , Retrospective Studies , Risk Assessment , Transplantation, Autologous , Treatment Outcome , Ulna Fractures/diagnostic imagingABSTRACT
BACKGROUND: Between 1989 and 1997, 17 patients underwent surgery for excision of primary cardiac tumour at the Department for Cardiovascular Surgery in Ljubljana. PATIENTS AND METHODS: There were 13 female (76.5%) and four male (23.5%) patients with an average age of 49+/-14 years (mean+/-SD). The study was retrospective. Special attention was paid to clinical presentation, method of diagnosis, elapsed time between the confirmed diagnosis and excision of the tumour, operatively determined location of tumour and post-operative course-diuresis in first 48 h, levels of CK and CK-MB, on first and on second day after operation and time of hospitalization. RESULTS: Thirteen patients (76.5%) had cardiac symptoms at the time of presentation (dyspnoea, syncope, vertigo, palpitations) and four (23. 5%) had embolic complications. In all the patients diagnosis was made by echocardiography. Average elapsed time between the confirmed diagnosis and the operation was 26+/-40 (mean+/-SD) days. Histological examination revealed myxoma in 15 patients (88.2%), one patient had lipoma and one malignant haemangiosarcoma. The most common location of tumour was in the left atrium (12 patients; 70. 6%). Post-operative complications occurred in four patients (23.5%); 76.5% of patients had diuresis in the range between 0.8 and 2.0 ml/h/kg; there was no post-operative oligouric renal failure. Average levels of both CK and CK-MB were statistically significantly lower on the second day after operation, there was no case of peri-operative myocardial infarction and post-operative death did not occur. One patient with multiple myxoma had two recurrences. CONCLUSIONS: Symptoms in patients with heart tumours, especially at the beginning of illness, are often uncharacteristic. Due to the non-specific presentation of cardiac tumours, a high index of suspicion is needed. The diagnostic method of choice is echocardiography. Operative removal of tumour is a safe procedure and recurrences in patients with benign tumours are rare.
