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Kardiologiia ; 28(8): 47-51, 1988 Aug.
Article in Russian | MEDLINE | ID: mdl-3199655

ABSTRACT

Combined effect of cordarone and ritmilen on myocardial electrophysiology was assessed in an acute medicated test, on the basis of electrophysiologic studies and transesophageal pacing test, in patients with resistant paroxysmal supraventricular tachycardia. The cordarone-ritmilen combination has proved efficient in 82.4% of cases and caused a significant change of the P-Q interval and effective refractory period (ERPav, ERPrv, ERPiv). The Q-T interval increased but never resulted in ventricular arrhythmias. Good antiarrhythmic effect was seen in 70.4% after 12 months. There were side effects in 10.7% of cases.


Subject(s)
Amiodarone , Disopyramide , Heart/drug effects , Adolescent , Adult , Aged , Amiodarone/therapeutic use , Arrhythmias, Cardiac/diagnosis , Arrhythmias, Cardiac/drug therapy , Arrhythmias, Cardiac/physiopathology , Cardiac Pacing, Artificial , Disopyramide/therapeutic use , Drug Evaluation , Drug Therapy, Combination , Electrocardiography , Electrophysiology , Female , Heart/physiopathology , Humans , Male , Middle Aged , Time Factors
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