[Hemocoagulation disorder and its impact on cerebral hemodynamics in patients with type I diabetes mellitus]. / Narushenie gemokoaguliatsii i ee vliianie na tserebral'nyiu gemodinamiky u bol'nykh sakharnym diabetom I tipa.

Indices were studied for the blood coagulation system in 132 patients with insulin-dependent diabetes mellitus (IDDM). The above indices tended to change toward hypercoagulation. The degree of changes was found to be related to duration and severity of illness. Patients presenting with a grave form DM more than 10 years in duration demobnstrated changes in their coagulograms suggesting the development of the chronic disseminated intravascular coagulation syndrome. Correlation has been established between fibrinogen and indices of reoencephalogram reflecting the state of the cerebral vascular system. The conclusion reached was to the effect that hyperfibrinogenemia makes for reduction in the brain pulse blood, is related to the development of venous discirculation, increase in the rigidity of cerebral vessels and heterogenuity of the blood filling in the brain.

[Disordered cerebral hemodynamics in diabetic patients (based on myelographic data)]. / Narushenie tserebral'noi gemodinamiki u bol'nykh sakharnym diabetom (po dannym mielografii).

Overall seventy-six patients with diabetes mellitus (DM) who ranged from 16 to 65 years old were examined. Of these, 62 subjects were given a diagnosis of insulin-dependent DM, 14 insulin-nondependent DM. Moderate severity course of the illness was documented in 32, severe--in 44 patients. All patients revealed a change in the condition of the cerebrovascular system. This was manifested by predominance of hypertonic type rheograms, increased vasomotor tone with vessels of all calibres, changes in the level of pulse blood filling, signs of varying degree venous hypertension. DM duration, severity, level of compensation were all related to the degree of cerebrovascular disturbances.

[A lipid metabolic disorder in diabetics]. / Narushenie lipidnogo obmena u bol'nykh sakharnym diabetom.

A total of 52 patients with diabetes mellitus (DM) who ranged from 15 to 60 years old were examined. Of these, 44 had type I DM, eight patients were afflicted with type 2 DM. 77 percent of the examinees were found out to develop hyperlipoproteinemia (HLP), with type 2b HLP having been diagnosed in 80 percent of the patients, type 4 HLP in 20 percent. The latter abnormality was seen in that group of patients presenting with a severe course of diabetes. In patients with type 1 DM HLP was not age-associated; it was developing in the presence of non-compensated carbohydrate metabolism, with duration of diabetes aggravating the severity of HLP. Type 2 DM patients revealed type 2b HLP with metabolic compensation being unsatisfactory. The above study suggests that lipid metabolism may be caused to return to normal by correction of carbohydrate metabolism, and leads to the belief that treatment of HLP is a worth-while exercise.