ABSTRACT
We proposed a mathematical model and estimated the parameters of adsorption of albumin-bilirubin complex to the surface of carbon pyropolymer. Design data corresponded to the results of experimental studies. Our findings indicate that modeling of this process should take into account fractal properties of the surface of carbon pyropolymer.
Subject(s)
Bilirubin/chemistry , Carbon/chemistry , Serum Albumin/chemistry , Adsorption , Bilirubin/blood , Fractals , Kinetics , Models, Chemical , Surface PropertiesABSTRACT
The pectin-vitamin composition (PVC) and its complex with active carbon (AC) was investigated for use as an oral sorbent to protect radionuclide (Sr-85, Cs-137) accumulation. PVC is composed of the natural mixture of cellulose, pectin (Ca-salt), flavonoides, vitamins of the B-group, PP and C. Investigation of PVC radioprotective action was carried out on the two groups of rats (n = 30) which received 1306 Bk/animal of Sr-85 or 343 Bk/animal of Cs-137 daily. One of the group of rats received every day also 300 mg of PVC. After 30 days level of Sr-85 was less by 56.6%, level of Cs = 137 was less by 27.6% in PVC-treated than in the control group (P < 0.05). Composite sorbent consisting of PVC and AC was slightly less effective in removing of Sr and Cs.
Subject(s)
Enterosorption/methods , Metals/poisoning , Pectins/therapeutic use , Radiation Injuries, Experimental/therapy , Animals , Cesium Radioisotopes/pharmacokinetics , Drug Combinations , Drug Evaluation, Preclinical , Female , Humans , Metals/pharmacokinetics , Poisoning/metabolism , Poisoning/therapy , Radiation Injuries, Experimental/metabolism , Rats , Strontium Radioisotopes/pharmacokinetics , Vitamins/therapeutic useABSTRACT
The alcohol dehydrogenase reaction on active charcoals has been studied. It is shown that the reaction rate on active charcoals decreases in comparison with usual conditions but the reaction being carried out for a longer period of time, the equilibrium shifts towards the NADH formation, which makes the NADH yield several times higher. A conclusion is made on the possibility of charcoals to influence the enzymic reactions in a living organism.
