Subject(s)
Sarcoma, Clear Cell/surgery , Soft Tissue Neoplasms/surgery , Tendons/surgery , Adolescent , Adult , Biopsy , Female , Humans , Lung Neoplasms/secondary , Lymphatic Metastasis , Male , Neoplasm Recurrence, Local/pathology , Neoplasm Recurrence, Local/surgery , Sarcoma, Clear Cell/pathology , Soft Tissue Neoplasms/pathology , Tendons/pathologyABSTRACT
A rare tumor of the mammary gland, built up of argyrophilic cells, with numerous metastases in the axillary lymph nodes is reported. Histochemical and electron-microscopic studied unequivocally demonstrated that this tumor belonged to the APUD system. The possible histogenesis of carcinoid tumor of the mammary gland is briefly discussed.
Subject(s)
Apudoma/pathology , Breast Neoplasms/pathology , Carcinoid Tumor/pathology , Apudoma/surgery , Breast Neoplasms/surgery , Carcinoid Tumor/surgery , Female , Humans , Lymphatic Metastasis , Mastectomy, Segmental , Middle AgedABSTRACT
Hypertrophy and hyperplasia of islet tissue, established by morphometry, were proved in the pancreas of rats, treated chronically for a period of 2 months (with urbason-50 mg/kg of body mass). B-cells were granulated. Structures with myelin-like form of membranes were observed in some of them by electron microscope. Mixed islet B-acinar cells were established as well. These data were possibly a morphological expression of stimulating action of urbason on B-cells of Langerhans islets.