ABSTRACT
This study compared plasma zinc levels in 15 children with active pulmonary tuberculosis, 15 malnourished children and 15 healthy children. Mean plasma zinc concentrations in children with tuberculosis (71.7 microg/dL) were not significantly different than the other 2 groups (72.5 and 76.9 microg/dL). The zinc status of the children with tuberculosis was evaluated after 2 months and 4 months of DOTS therapy. The serum zinc level during anti-tuberculosis therapy decreased after 1 month and then recovered to the initial level after 4 months of treatment.
Subject(s)
Antitubercular Agents/adverse effects , Child Nutrition Disorders/drug therapy , Tuberculosis, Pulmonary/drug therapy , Zinc , Blood Proteins/metabolism , Case-Control Studies , Child , Child Nutrition Disorders/blood , Child Nutrition Disorders/complications , Child, Preschool , Directly Observed Therapy/adverse effects , Drug Monitoring , Female , Humans , Infant , Iran , Male , Nutrition Assessment , Nutritional Status , Serum Albumin/metabolism , Statistics, Nonparametric , Time Factors , Treatment Outcome , Tuberculosis, Pulmonary/complications , Zinc/blood , Zinc/deficiencyABSTRACT
This study compared plasma zinc levels in 15 children with active pulmonary tuberculosis, 15 malnourished children and 15 healthy children. Mean plasma zinc concentrations in children with tuberculosis [71.7 microg/dL] were not significantly different than the other 2 groups [72.5 and 76.9 microg/dL]. The zinc status of the children with tuberculosis was evaluated after 2 months and 4 months of DOTS therapy. The serum zinc level during anti-tuberculosis therapy decreased after 1 month and then recovered to the initial level after 4 months of treatment
