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J Vis Exp ; (150)2019 08 12.
Article in English | MEDLINE | ID: mdl-31449264

ABSTRACT

The Translational Brain Mapping Program at the University of Rochester is an interdisciplinary effort that integrates cognitive science, neurophysiology, neuroanesthesia, and neurosurgery. Patients who have tumors or epileptogenic tissue in eloquent brain areas are studied preoperatively with functional and structural MRI, and intraoperatively with direct electrical stimulation mapping. Post-operative neural and cognitive outcome measures fuel basic science studies about the factors that mediate good versus poor outcome after surgery, and how brain mapping can be further optimized to ensure the best outcome for future patients. In this article, we describe the interdisciplinary workflow that allows our team to meet the synergistic goals of optimizing patient outcome and advancing scientific understanding of the human brain.


Subject(s)
Academic Medical Centers/methods , Brain Mapping/methods , Brain/diagnostic imaging , Intraoperative Neurophysiological Monitoring/methods , Precision Medicine/methods , Translational Research, Biomedical/methods , Brain/surgery , Brain Neoplasms/diagnostic imaging , Brain Neoplasms/pathology , Brain Neoplasms/surgery , Female , Humans , Magnetic Resonance Imaging/methods , Male , Neurosurgical Procedures/methods
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