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Tsitol Genet ; 9(5): 461-1, 1975.
Article in Russian | MEDLINE | ID: mdl-1179497

ABSTRACT

Studies in the effect of a complex of inoculating preparations (poliovaccine, APDD-vaccine, smallpox vaccine, measles vaccine) on dividing cells of bone marrow in mice in line CC57Br showed that a reduction of the interval between introduction of vaccines different in the antigenic respect from 14 days to 4 days results in an increase in frequency of structural chromosomal aberrations 1-2 months after the whole course of inoculations.


Subject(s)
Bone Marrow Cells , Bone Marrow/ultrastructure , Chromosomes/drug effects , Vaccination , Vaccines/pharmacology , Animals , Chromosome Aberrations , Diphtheria Antitoxin/pharmacology , Drug Combinations , Measles Vaccine/pharmacology , Mice , Mice, Inbred C57BL , Pertussis Vaccine/pharmacology , Poliovirus Vaccine, Inactivated/pharmacology , Smallpox Vaccine/pharmacology , Tetanus Antitoxin/pharmacology , Time Factors
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