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Antibiot Khimioter ; 35(1): 8-11, 1990 Jan.
Article in Russian | MEDLINE | ID: mdl-2334246

ABSTRACT

The stages of spore development, the most favourable for electrophoretic separation of the spores, were studied in the cultures producing kanamycin and tylosin. The stage of sporulating was shown to be the optimal. The step-by-step procedure for preparing the spores for electrophoresis is described. There were observed distinctions in the fatty acid spectrum of the cells in the cultures grown from electrophoretic fractions of the spores with different antibiotic production capacity.


Subject(s)
Kanamycin/biosynthesis , Spores, Bacterial/isolation & purification , Streptomyces/physiology , Tylosin/biosynthesis , Culture Media , Electrophoresis/methods , In Vitro Techniques , Streptomyces/metabolism
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