[The dynamics of antibody formation in patients with fresh forms of syphilis treated by the single-course method with the novocaine salt of benzylpenicillin]. / Dinamika antiteloobrazovaniia u bol'nykh svezhimi formami sifilisa, lechennykh po odnokusovoi metodike novokainovoi sol'iu benzilpenitsillina.

Investigation of the blood sera of patients with fresh syphilis forms before, immediately after, and in 6-18 months after treatment has confirmed a high sensitivity of the serologic tests for syphilis used in this country. The results of dynamic serologic monitoring of patients have demonstrated high efficacy of the therapeutic method used.

[The preservation of strains of pathogenic Treponema pallidum in BALB/c mice]. / Sokhranenie shtammov patogennykh blednykh treponem na myshakh linii BALB/c.

A clinical and serologic follow-up of 307 BALB/c mice and 12 rabbits injected with the blood and brain and spinal tissue of mice infected with 5 strains of T. pallidum has demonstrated the possibility of a prolonged (up to 465 days) preservation of pathogenic T. pallidum strains in these mice, as well as the regularity of a syphilitic infection development in rabbits. This permits recommending T. pallidum pathogenic strains to be maintained in mice at laboratories of institutions for skin and sexually transmitted diseases where experimental and diagnostic studies with the use of specific serologic tests for syphilis are carried out.

[The effect of nicotinamide and nicotinic and ascorbic acids on the penicillin concentration in the blood serum and tissues of rabbits]. / Vliianie nikotinamida, nikotinovoi i askorbinovoi kislot na kontsentratsiiu penitsillina v syvorotke krovi i tkaniakh krolikov.

Measurements of penicillin concentrations in the blood sera and tissues of rabbits have revealed a reduction of this antibiotic levels as the doses of injected ascorbic acid grew. A combination of benzylpenicillin with ascorbic and nicotinic acids improved penicillin penetration into experimental animals' tissues.