Subject(s)
Anesthetics, Intravenous/pharmacology , Apoptosis/drug effects , HSP70 Heat-Shock Proteins/metabolism , Neuroprotective Agents/pharmacology , Thiopental/pharmacology , Barbiturates/pharmacology , Cell Line, Tumor , DNA/metabolism , DNA-Binding Proteins/metabolism , Heat Shock Transcription Factors , Humans , Transcription Factors/metabolismABSTRACT
BACKGROUND: The survival rate of cemented knee prosthesis depends among other factors on optimal cement-bone contact, nevertheless no standard exists for cementing technique of tibial components. The aim of this study was to determine which tibial surface preparation technique leads to the best bone-cement contact. MATERIALS AND METHODS: HUMAN TIBIAL PLATEAU SPECIMENS WERE CLEANED IN FOUR DIFFERENT WAYS BEFORE CEMENTING: a) no cleaning, b) manual syringe irrigation, c) fracture brush cleaning, and d) pulsatile jet-lavage. The specimens were cut into transverse sections and the bone cement contact distance was calculated for every 10 mm and the cement penetration depth was measured. Both values were statistically analyzed (ANOVA). RESULTS: The longest bone-cement contact (62 mm) was seen after PJL, the shortest (10.6 mm) after no cleaning at all. The deepest cement penetration (4.1 mm) again was seen after PJL, the least (0.7 mm) after no cleaning. Statistically, PJL yielded the longest bone-cement contact and deepest cement penetration. CONCLUSION: The results supports the use of pulsatile jet-lavage before cementing tibial components in knee arthroplasty.
