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Gan To Kagaku Ryoho ; 34(9): 1477-9, 2007 Sep.
Article in Japanese | MEDLINE | ID: mdl-17876150

ABSTRACT

A 70-year-old man with abdominal pain and anemia was diagnosed with duodenal cancer upon upper gastrointestinal endoscopy and biopsy. Pancreatoduodenectomy was performed. Pathological findings were duodenal cancer, T 4 SI (Panc) N0P0V0A0H0. Three months after operation, abdominal CT showed multiple liver metastasis. He then underwent combined chemotherapy consisting of two weeks administration of S-1 (80 mg/body) followed by one week rest and injections of docetaxel (40 mg/body) every three weeks as one course. Metastatic tumors were gradually reduced and successfully controlled,and there was no other recurrence until he died about three years later of another illness. Combined S-1 and docetaxel chemotherapy is known to be effective for esophageal cancer, gastric cancer and other digestive cancer, as well as for duodenal cancer.


Subject(s)
Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Duodenal Neoplasms/pathology , Liver Neoplasms/drug therapy , Liver Neoplasms/secondary , Aged , Antineoplastic Agents/administration & dosage , Docetaxel , Drug Combinations , Duodenal Neoplasms/drug therapy , Duodenal Neoplasms/surgery , Humans , Male , Oxonic Acid/administration & dosage , Taxoids/administration & dosage , Tegafur/administration & dosage
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