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Transient Deformation of Neutrophils in Kawasaki Disease.
Koike, Yumi; Yanagisawa, Ryu; Ogiso, Yoshifumi; Cho, Yoshiaki; Minami, Kisei; Takeuchi, Kouichi; Sakashita, Kazuo; Higuchi, Tsukasa.
J Pediatr ; 173: 238-241.e1, 2016 06.
Article in English | MEDLINE | ID: mdl-27039225

ABSTRACT

In the treatment of Kawasaki disease, resistance to high-dose immunoglobulin intravenous (IGIV) can occur. The neutrophil morphology analyses in 17 patients revealed that transient pseudo-Pelger-Huët anomaly was more frequently detected in the IGIV-resistant group. This finding may aid the prediction of IGIV resistance.


Subject(s)
Drug Resistance , Immunoglobulins, Intravenous/therapeutic use , Mucocutaneous Lymph Node Syndrome/drug therapy , Pelger-Huet Anomaly/diagnosis , Child, Preschool , Female , Humans , Male , Pelger-Huet Anomaly/complications , Retrospective Studies
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