[Effect of dalargin on energy metabolism of heart contractile function in acute blood loss]. / Vliianie dalargina na énergoobespechenie sokratitel'noi funktsii serdtsa pri ostroi krovopotere.

The authors studied the mechanisms of disorders of energy provision of myocardial contractility in rabbits in hemorrhagic shock and appraised the efficacy of a new Soviet-produced agent dalargin possessing an antiadrenergic property. It is shown that dalargin exerts a significant effect on the condition of the cardiovascular system and the function of the myocardial mitochondria (MC). The effect differed depending on the time of the injection and the condition of the organism. Increase of the heart contractive function, improvement of MC function, and prolonged survival of the animals were encountered only in rabbits who received dalargin 30 minutes after blood loss. The mechanisms of the effects of dalargin in acute blood loss are discussed.

[Slow potentials of the receptive field of the ciliary body and their relationship to regulation of intraocular pressure]. / Medlennye potentsialy retseptornogo polia tsiliarnogo tela i ikh sviaz' s reguliatsiei vnutriglaznogo davleniia.

Spontaneous slow potentials with amplitude ranging from 25 mcV to 1.3 mV and wave duration from 600 to 6000 msec was recorded in the receptive area of the ciliary body. The same potentials persisted even 15--20 min after the death of animal in the enucleative eye as well as in the isolated preparation of the ciliary body with sclera. The rise of the intraocular pressure up to 30--35 mm Hg augments the potentials whereas further rise up to 45 mm Hg and more suppresses them. Electrostimulation acts in a similar way: square pulses of 25 mcV augment the potentials' amplitude whereas the 250 mcV pulses reduce it.