A circular waste bioeconomy development model in the Ecuadorian fishery industry: the impact of government strategy on supply chain integration and smart operations.

This study develops a set of measures to address the interrelationship among circular waste-based bioeconomy (CWBE) attributes, including those of government strategy, digital collaboration, supply chain integration, smart operations, and a green supply chain, to build a circular bioeconomy that feeds fish waste back into the economy. CWBE development is a potential solution to the problem of waste reuse in the fish supply chain; however, this potential remains untapped, and prior studies have failed to provide the criteria to guide its practices. Such an analytical framework requires qualitative assessment, which is subject to uncertainty due to the linguistic preferences of decision makers. Hence, this study adopts the fuzzy Delphi method to obtain a valid set of attributes. A fuzzy decision-making trial and evaluation was applied to address the attribute relationships and determine the driving criteria of CWBE development. The results showed that government strategies play a causal role in CWBE development and drive digital collaboration, smart operations, and supply chain integration. The findings also indicated that smart manufacturing technology, organizational policies, market enhancement, supply chain analytics, and operational innovation are drivers of waste integration from fisheries into the circular economy through waste-based bioeconomy processes.

Temporal recruitment of base excision DNA repair factors in living cells in response to different micro-irradiation DNA damage protocols.

Laser micro-irradiation across the nucleus rapidly generates localized chromatin-associated DNA lesions permitting analysis of repair protein recruitment in living cells. Recruitment of three fluorescently-tagged base excision repair factors [DNA polymerase ß (pol ß), XRCC1 and PARP1], known to interact with one another, was compared in gene-deleted mouse embryonic fibroblasts and in those expressing the endogenous factor. A low energy micro-irradiation (LEMI) forming direct single-strand breaks and a moderate energy (MEMI) protocol that additionally creates oxidized bases were compared. Quantitative characterization of repair factor recruitment and sensitivity to clinical PARP inhibitors (PARPi) was dependent on the micro-irradiation protocol. PARP1 recruitment was biphasic and generally occurred prior to pol ß and XRCC1. After LEMI, but not after MEMI, pol ß and XRCC1 recruitment was abolished by the PARPi veliparib. Consistent with this, pol ß and XRCC1 recruitment following LEMI was considerably slower in PARP1-deficient cells. Surprisingly, the recruitment half-times and amplitudes for pol ß were less affected by PARPi than were XRCC1 after MEMI suggesting there is a XRCC1-independent component for pol ß recruitment. After LEMI, but not MEMI, pol ß dissociation was more rapid than that of XRCC1. Unexpectedly, PARP1 dissociation was slowed in the absence of XRCC1 as well with a PARPi after LEMI but not MEMI, suggesting that XRCC1 facilitates PARP1 dissociation from specific DNA lesions. XRCC1-deficient cells showed pronounced hypersensitivity to the PARPi talazoparib correlating with its known cytotoxic PARP1 trapping activity. In contrast to DNA methylating agents, PARPi only minimally sensitized pol ß and XRCC1-deficient cells to oxidative DNA damage suggesting differential binding of PARP1 to alternate repair intermediates. In summary, pol ß, XRCC1, and PARP1 display recruitment kinetics that exhibit correlated and unique properties that depend on the DNA lesion and PARP activity revealing that there are multiple avenues utilized in the repair of chromatin-associated DNA.

Developing a hierarchical framework for assessing the strategic effectiveness of sustainable waste management in the Somaliland construction industry.

This study contributes to develop a hierarchical framework for assessing the strategic effectiveness of waste management in the construction industry. This study identifies a valid set of strategic effectiveness attributes of sustainable waste management (SWM) in construction. Prior studies have neglected to develop a strategic effectiveness assessment framework for SWM to identify reduce, reuse, and recycle policy initiatives that ensure waste minimization and resource recovery programs. This study utilizes the fuzzy Delphi method to screen out nonessential attributes in qualitative information. This study initially proposes a set of 75 criteria; after two rounds of assessment, consensus regarding 28 criteria is achieved among experts, and the 28 criteria are validated. Fuzzy interpretive structural modeling divides the attributes into various elements. The modeling constructs a six-level model that depicts the interrelationships among the 28 validated criteria as a hierarchical framework, and it finds and ranks the optimal drivers for practical improvement. This study integrates the best-worst method to measure the weights of different criteria in the hierarchical strategic effectiveness framework. The findings reveal that waste management operational strategy, construction site waste management performance, and the mutual coordination level are the top aspects for assessing strategic effectiveness in the hierarchical framework. In practice, the waste reduction rate, the recycling rate, water and land usage, the reuse rate, and noise and air pollution levels are identified to assist policymakers in evaluation. The theoretical and managerial implications are discussed.

Identifying the evolution of ecological poverty alleviation efficiency and its influencing factors: evidence from counties in Northeast China.

Ecological poverty alleviation (EPA) is an effective strategy to address the vicious circle of poverty and environmental destruction in poor areas. However, it remains controversial whether this strategy has really succeeded in this respect. Previous research investigated the impact of a certain factor on EPA, and only few studies integrated them to explore their differential effects, thereby overlooking the complexity of EPA. Therefore, this study quantified the overall efficiency of the EPA strategies of 28 poor counties in three provinces of Northeast China from 2005 to 2018 by using a super-efficiency slacks-based measure model. This model can take into account undesirable outputs; as such, it has significant advantages in measuring the coordination among economic and social development and environmental protection. The Tobit model was used to explore the factors influencing EPA efficiency. The results show that, first, the majority of counties investigated had an EPA efficiency below the overall national average. Second, as for the factors influencing EPA efficiency, it was found that (1) GDP per capita and investment in environmental governance favored EPA efficiency, as they are conducive to stimulating regional consumption dynamics and achieving green economic development; (2) science and technology expenditure and urbanization were not conducive to EPA efficiency; and (3) industrial structure and trade had insignificant effects on EPA efficiency, due to the small scale of industry and the inadequacy of the policy system. This study assessed EPA efficiency from a holistic perspective, and addressed the controversies over EPA's influencing factors, thereby providing an effective method to conduct regional EPA assessment and improve EPA performance in poor regions of China.

Resource saving and carbon footprint reduction potential of urban symbiosis strategy in express packaging waste recycling network.

The booming express delivery industry corresponds to the environmental challenges caused by massive express packaging waste (EPW). An efficient logistics network is necessary link to support EPW recycling. This study, therefore, designed a circular symbiosis network for EPW recycling based on urban symbiosis strategy. The treatment of EPW in this network includes reuse, recycling and replacing. An optimization model with multi-depot collaboration combining material flow analysis and optimization methods was developed and a hybrid non-dominated sorting genetic algorithm-II (NSGA-II) was designed as technical support for designing the circular symbiosis network while quantitatively assessing the economic and environmental benefits of the network. The results show that the designed circular symbiosis option has better resource saving and carbon footprint reduction potential than both the business as usual option and circular symbiosis option without service collaboration. In practice, the proposed circular symbiosis network can save EPW recycling costs and reduce carbon footprint. This study provides a practical guideline for the application of urban symbiosis strategies to help urban green governance and the sustainable development of express companies.

Spodoptera litura larvae are attracted by HvAV-3h-infected S. litura larvae-damaged pepper leaves.

BACKGROUND: Herbivore-induced plant volatiles (HIPVs) are important self-defense outputs of pepper plants to resist insect pests. Ascoviruses are pathogenic to the larvae of most lepidopteran vegetable pests. However, whether Heliothis virescens ascovirus 3h (HvAV-3h)-infected Spodoptera litura larvae can change pepper leaf HIPVs is not well understood. RESULTS: Spodoptera litura larvae preferred S. litura-infested leaves, and this preference was stronger with longer duration of S. litura infestation. In addition, S. litura larvae significantly chose pepper leaves damaged by HvAV-3h-infected S. litura over the healthy pepper leaves. Results also showed that S. litura larvae preferred leaves mechanically damaged and treated with oral secretions from HvAV-3h infected-S. litura larvae in a simulation test. We captured the volatiles emitted by leaves under six treatments. Results showed that the volatile profile changed with the different treatments. Testing of volatile blends, prepared to the proportion released showed that the blend from simulated HvAV-3h-infected S. litura larvae-damaged plants was the most attractive to S. litura larvae. Further, we also found that some of the compounds significantly attracted S. litura larvae at specific concentrations. CONCLUSION: HvAV-3h-infected S. litura can alter the release of HIPVs in pepper plants and thus become more attractive to S. litura larvae. We speculate that this may be due to alterations in the concentration of some compounds (such as geranylacetone and prohydrojasmon) affecting the behavior of S. litura larvae. © 2023 Society of Chemical Industry.

Nexus amongst environmental regulations, carbon emission intensity and technological innovation in China's construction industry.

China's construction industry confronts with the dilemma of carbon emissions in adjusting the environmental regulations. Many studies are neglected on discovering the potential nexus amongst environmental regulations (ERs), technological innovation (TI) and CEI (CEI) and ignores the relationships amongst TI for reducing CEI. To mitigate this gap, this study bridges institutional theory to integrate the practices in the construction industry. This study applies a panel dataset on the construction industry from 30 provinces during 2004-2018 and uses it with a two-step system-generalised method of moments for analysis. The proposed method enables the prevention of the interference of the heteroscedasticity problem and improves certain analytical efficiency. The results are as a guideline for policymakers in rechecking the policies and regulations adequacy. The findings indicate that (1) the forced emission reduction effect is proven by command-and-control and market-based ERs, which can inhibit CEI; (2) voluntary ERs have an inverted U-shaped nexus with CEI; in other words, the green paradox effect shifts to the forced emission reduction effect once the intensity of voluntary ERs increases; and (3) market-based and voluntary ERs reduce CEI effectively by using TI as the mediator in construction industry.

Uncovering four domains of energy management in palm oil production: a sustainable bioenergy production trend.

This study aims to identify current and future research trends in sustainable bioenergy production. The systematic review is conducted using a social network analysis method. The data were collected from the Web of Science and Scopus database (2010-2021). Out of the 1747 articles reviewed, 100 were found to be relevant for thematic analysis. The results uncovered four domains of palm oil biodiesel production for sustainable energy management: (1) renewable energy, (2) biodiesel, (3) bioenergy, and (4) life cycle assessment. This study has proposed a sustainable bioenergy production framework based on the four main domains. The framework sheds light on the future of sustainable bioenergy production. The findings indicate the potential growth of the research topic, including sustainable bioenergy, palm oil biodiesel, energy management, and carbon emissions reduction. Future research must incorporate the energy management framework to design a sustainable energy management ecosystem strategy. In addition, the industry must comply with the international sustainability standard and sustainable development goals to manage the energy supply chain and consistency of palm oil biodiesel production.

Understanding barriers and motivations in solid waste management from Malaysian industries: a comparative analysis.

The objective of this study is to explore the similarities and differences in the barriers and motivations between the plastic and resins and food and beverages industries as these two industries are the major contributors of solid waste in Malaysia. Prior studies are lacking with regard to explaining the barriers and motivations in solid waste management from the Malaysian context. This study is focused on 10 firms from the plastics and resins industry and 9 from the food and beverages industry in Malaysia. Through Rasch measurement theory, the results indicate that the barriers of lack of skills and qualifications and lack of closed-loop control and the motivations of cost savings and a business model are performed differently. The findings further confirm that the lack of skills and qualifications is a more difficult barrier to overcome than the lack of closed-loop control, while the motivation factor of a business model is more difficult to achieve than cost savings. In terms of practical contribution, this study provides results that can help policy makers in Malaysia to close the gaps present regarding the adoption of solid waste management practices and to devise appropriate incentives. The study also supports managers of companies in regard to working on the most pressing hindering and promoting factors in the field of solid waste management.

HDAC3-a key target for preventing organ ischemia-reperfusion injury / 中国药理学通报

Histone deacetylase 3 (HDAC3) plays an important role in chromatin remodeling, which in turn regulates gene transcription, so HDAC3 is involved in the pathophysiology of various diseases through epigenetic regulation. Organ ischemia-reperfusion injury (I R I) is a pathophysiological process that leads to the development of a variety of diseases such as delayed neuronal necrosis, irreversible shock, myocardial infarction, acute organ failure and organ transplant rejection. In this paper we review the pathophysiological function of HDAC3 and its role in the development of IRI in human parenchymal organs, and also explore the therapeutic value of HDAC3 in IRI.

Research progress of HDACs and associated inhibitors on regulation of acute lung injury / 中国药理学通报

Acute lung injury ( ALI) and its most extreme form a-cute respiratory distress syndrome ( ARDS) are lung diseases with high morbidity and mortality. There is no effective therapeutic intervention until now for its complicated pathophysiologi-cal processes and sophisticated regulatory mechanism. Histone deacetylases (HDACs) are a family of proteins with deacetylase activity. Studies have shown that HDACs are involved in the pathophysiological processes of ALI/ARDS, including inflammatory responses,endothelial permeability,oxidative stresses,alveolar fluid clearance and lung tissue repairment. Simultaneously, the use of HDACs inhibitors (HDACIs) can interfere with ALI/ ARDS progression. In this review we describe and summarize the pathophysiological processes and the underlying mechanisms in ALI/ARDS regulated by HDACs and HDACIs in detail, in order to provide the basis for the clinical application of HDACs-targe- ted agents and indicate directions for future study.

Large-scale transcriptomic analysis of coding and non-coding pathological biomarkers, associated with the tumor immune microenvironment of thyroid cancer and potential target therapy exploration.

Papillary thyroid carcinoma (PTC) is the most prevalent endocrine malignancy with a steadily increasing global incidence in recent decades. The pathogenesis of PTC is poorly understood, and the present diagnostic protocols are deficient. Thus, identifying novel prognostic biomarkers to improve our understanding of the mechanisms of pathogenesis, diagnosis, and designing therapeutic strategies for PTC is crucial. In this study, we integrated 27 PTC transcriptomic datasets and identified overlapping differentially expressed genes (DEGs) and differentially expressed microRNAs, collectively known as thyroid tumor-enriched proteins (TTEPs), and TTEmiRs, respectively. Our integrated bioinformatics analysis revealed that TTEPs were associated with tumor stages, poor surgical outcomes, distant metastasis, and worse prognoses in PTC cohorts. In addition, TTEPs were found to be associated with tumor immune infiltrating cells and immunosuppressive phenotypes of PTC. Enrichment analysis suggested the association of TTEPs with epithelial-to-mesenchymal transition (EMT), cell-matrix remodeling, and transcriptional dysregulation, while the TTEmiRs (miR-146b-5p and miR-21-5p) were associated with the modulation of the immune response, EMT, migration, cellular proliferation, and stemness. Molecular docking simulations were performed to evaluate binding affinities between TTEPs and antrocinnamomin, antcin, and antrocin, the bioactive compounds from one of the most reputable Taiwan indigenous medicinal plants (Antrodia camphorata). Our results revealed that antcin exhibited higher binding efficacies toward FN1, ETV5, and NRCAM, whereas antrocin demonstrated the least. Among the targets, fibronectin (FN1) demonstrated high ligandability potential for the compounds whereas NRCAM demonstrated the least. Collectively, our results hinted at the potential of antcin for targeting TTEPs. In conclusion, this comprehensive bioinformatics analysis strongly suggested that TTEPs and TTEmiRs could be used as potential diagnostic biomarker signatures and be exploited as potential targets for therapeutics development.

Inventory decisions on the transportation system and carbon emissions under COVID-19 effects: A sensitivity analysis.

The COVID-19 pandemic has created multiple problems in the existing transportation system. The contribution of this study is to guide logistics managers as they make ordering decisions within a disrupted transportation system. In the overall supply chain system, inventory decisions have been either compromised or challenged. Traditional inventory decisions that consider preplanned transportation facilities (and speeds) are currently becoming obsolete, predominantly in post-COVID times due to delays in the delivery of products and higher delivery costs. Therefore, businesses such as retailers must align ordering and pricing decisions to maintain a sustainable profit. To address this issue, this study investigates optimum inventory decisions under the pandemic's effects while considering the transportation cost as proportional to COVID-19 intensity. This study also considers product deterioration, time-dependent holding costs, price-dependent demands, and carbon emissions from vehicle operation and intends to establish a harmonious relationship among these attributes. The optimization of green technology investment is studied to reduce emissions due to transportation. Some theoretical derivations and numerical examples are given, and they are followed by a sensitivity analysis to extract important managerial insights into the effect of COVID-19. The manager can set an optimal selling price and the cycle length by carefully planning the number of trips in considering the rate of the outbreak and its effect on the increasing transportation cost.

An optimum balance among the reduction in ordering cost, product deterioration and carbon emissions: a sustainable green warehouse.

This study involves an optimum balance between ordering cost reduction and product deterioration in controllable carbon emissions for a sustainable green warehouse. The sensitivity analysis is to simulate the impact of those attributes. Industries are foraging to find a proper balance between the use of fossil fuels and reducing carbon emissions, as burning fossil fuels is also indispensable for industrialization. Carbon can emit through inevitable logistic activities in the chains (e.g., lighting, heating, air-conditioning, product deterioration). An industry always attempts to curb those emissions through energy-efficient green technology. The green warehouse is a popular store system in present supply chains to limit the carbons. Product deterioration, particularly for perishable items, is also important for a practitioner to decide how to preserve a perishable product for maximum shelf-life. There is a common tendency among industries to increase order frequencies and volumes in search of a better preservation strategy, increasing the ordering cost and the probability of carbon emissions due to increased transportation. A realistic mathematical model is proposed based on those decision parameters by a sensitivity analysis to demonstrate the impacts. The results showed an increase of 46.30% profit is achieved when all three proposed reduction attributes, but shortages are considered. This improvement is significant without shortage, whereas the increased profit is 94.75%.

Impacts of the COVID-19 pandemic on household food waste behaviour: A systematic review.

Food waste has adverse economic, social, and environmental impacts and increases the prevalence of food insecurity. Panic buying at the beginning of the COVID-19 outbreak raised serious concerns about a potential rise in food waste levels and higher pressure on waste management systems. This article aims to investigate the impact of COVID-19 on food waste behaviour and the extent to which it occurs using the systematic review method. A total of 38 articles were identified and reviewed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The findings showed that the COVID-19 pandemic led to reductions in household food waste in most countries. Several changes in shopping and cooking behaviours, food consumption, and managing inventory and leftovers have occurred due to COVID-19. Based on these insights, we predicted that some desirable food-management habits would be retained, and others would roll back in the post-COVID-19 world. The review contributes to the food waste literature by offering a comprehensive overview of behavioural changes during the COVID-19 pandemic and future research directions.

Monitoring DNA polymerase ß mitochondrial localization and dynamics.

Mouse fibroblasts lacking (null) DNA polymerase ß (pol ß) were transfected with fluorescently tagged pol ß and stained with biomarkers to allow visualization within living cells by confocal microscopy. Transient transfection resulted in varying pol ß expression levels. Separating cells into three groups based on pol ß fluorescence intensity and morphological distribution, permitted analysis of the concentration dependence and spatial distribution of cytoplasmic pol ß. Colocalization between pol ß and mitochondria was pol ß concentration dependent. A decrease in overlap with nucleoids containing mitochondrial DNA (mtDNA) was observed at the highest pol ß intensity where pol ß exhibits a tubular appearance, suggesting the ability to load elevated levels of pol ß into mitochondria readily available for relocation to damaged mtDNA. The dynamics of pol ß and mitochondrial nucleoids were followed by confocal recording of time series images. Two populations of mitochondrial nucleoids were observed, with and without pol ß. Micro-irradiation, known to form DNA single-strand breaks, in a line across nucleus and cytoplasm of pol ß stably transfected cells enhanced apparent localization of pol ß with mitochondria in the perinuclear region of the cytoplasm near the nuclear membrane. Exposure of pol ß expressing cells to H2O2 resulted in a time-dependent increase in cytoplasmic pol ß observed by immunofluorescence analysis of fixed cells. Further screening revealed increased levels of colocalization of pol ß with a mitochondrial probe and an increase in oxidative DNA damage in the cytoplasm. ELISA quantification confirmed an increase of an oxidative mitochondrial base lesion, 7,8-dihydro-8-oxoguanine, after H2O2 treatment. Taken together, the results suggest that pol ß is recruited to mitochondria in response to oxidatively-induced mtDNA damage to participate in mtDNA repair.

Solid waste material reuse analysis: filling the road subgrade with riverway silt and sediment.

This study proposes to explore solid waste material (SWM) reuse of the riverway silt and sediment, and examines the impacts of chemical composition on road construction through sensitivity analysis. Considering the characteristics of silt mixture, it is necessary to investigate the modified materials to improve the mechanical feasibility for subgrade filling. In this study, the water content of riverway silt and sediments was found to be important to determine the selection and content of modified materials. Specifically, the riverway silt and sediment with low water content could be improved effectively with 6 to 8% lime. Compared to the original sludge, the improved mixture had better particle size and permeability, and the carrying capacity also grew 2 to 3 times. On the other hand, the reuse of riverway silt and sediment with high water content over 40% was provided with multiple schemes. Among them, the modification scheme of construction waste or garbage slag showed well mechanical properties and environmental benefits in the sensitivity analysis, especially for the high water content sludge modified by the mixture of garbage slag and lime. The California bearing ratio (CBR2.5) was 2 to 5 times higher than the original silt, which would promote the reuse of multiple solid wastes in road construction. Finally, this study puts forward engineering measures to prevent heavy metals from polluting the water and soil environment by silt-improved soil roadbeds, and the improved riverway silt and sediment roadbeds were proved to be safe and reliable for the environment during service.

Consumption-based CO2 emissions accounting and scenario simulation in Asia and the Pacific region.

This study uses a consumer-based accounting approach to evaluate the CO2 emission factors of 17 countries in Asia and the Pacific region by including all emissions in the supply chain from commodity location to final consumption location in country consumption patterns. In addition, the number of emissions connected with each country's consumption of products and services in Asia and the Pacific region has received little attention. This study contributes to understanding the effects of countries' consumption of products and services on carbon emission peaks and formulates efficient carbon mitigation plans for governments and decision-makers. Accelerating economic growth and industrialization have posed significant challenges to global carbon mitigation efforts and climate change responses. The Monte Carlo simulation technique was used to create a dynamic scenario simulation model to investigate possible future peaks in the carbon emissions of countries in Asia and the Pacific region while taking into account factor uncertainties. The results show that total consumption-based CO2 emissions are remarkable in three Asian countries, including China (387,451.95 metric tons Mt CO2), Japan (185,259.60 Mt CO2), and India (100,720.46 Mt CO2). In South Korea, Brunei, and Taiwan, annual consumption emissions are 1.77, 1.62, and 1.49 tons of CO2 per person, respectively. In terms of final consumption, the household sector is the most noteworthy contributor to consumption-based emissions, accounting for 27-56%. The household sector probably peaks at 19.7 Gt CO2 as per the dynamic scenario simulation. For the three other types of final demand, government expenditure will possibly reach a maximum of 44.0 Gt CO2 in the next 30 years, while capital formation will probably reach its highest emission level at 149.5 Gt CO2.

Transcriptomic discovery of a theranostic signature (SERPINE1/MMP3/COL1A1/SPP1) for head and neck squamous cell carcinomas and identification of antrocinol as a candidate drug.

Head and neck squamous cell carcinomas (HNSCC) are prevalent malignancies with a disappointing prognosis, necessitating the search for theranostic biomarkers for better management. Based on a meta-analysis of transcriptomic data containing ten clinical datasets of HNSCC and matched nonmalignant samples, we identified SERPINE1/MMP3/COL1A1/SPP1 as essential hub genes as the potential theranostic biomarkers. Our analysis suggests these hub genes are associated with the extracellular matrix, peptidoglycans, cell migration, wound-healing processes, complement and coagulation cascades, and the AGE-RAGE signaling pathway within the tumor microenvironment. Also, these hub genes were associated with tumor-immune infiltrating cells and immunosuppressive phenotypes of HNSCC. Further investigation of The Cancer Genome Atlas (TCGA) cohorts revealed that these hub genes were associated with staging, metastasis, and poor survival in HNSCC patients. Molecular docking simulations were performed to evaluate binding activities between the hub genes and antrocinol, a novel small-molecule derivative of an anticancer phytochemical antrocin previously discovered by our group. Antrocinol showed high affinities to MMP3 and COL1A1. Notably, antrocinol presented satisfactory drug-like and ADMET properties for therapeutic applications. These results hinted at the potential of antrocinol as an anti-HNSCC candidate via targeting MMP3 and COL1A1. In conclusion, we identified hub genes: SERPINE1/MMP3/COL1A1/SPP1 as potential diagnostic biomarkers and antrocinol as a potential new drug for HNSCC.

Understanding the barriers to sustainable solid waste management in society 5.0 under uncertainties: a novelty of socials and technical perspectives on performance driving.

This study contributes to identifying a valid and reliable set of barriers to sustainable solid waste management framework rooted in society 5.0 perspectives in Taiwan. The SSWM-related causal interrelationships within the proposed hierarchical structure, and critical barriers for the practical improvement and enhancement of SSWM performance are identified as preference enriching both literature and practices. In nature, the hierarchical structure is with the causal interrelationships under uncertainties. The perspective empowers the creation of a new biosphere based on technological progress, but in the sustainable solid waste management field, it is difficult to encounter and shape the systematized processes due to barriers and challenges. To address this shortcoming, this study evaluates the technical challenges faced in the field of sustainable solid waste management toward society 5.0. The valid attributes are usually described the qualitative information. The fuzzy Delphi method is applied to acquire the valid and reliable attributes. Fuzzy decision-making trial and evaluation laboratory experiment is to visualize the causal interrelationships among the attributes. Choquet integral with respect to the nonadditive attributes over the valid set provides an overall perspective function. The results establish an understanding of sustainable solid waste management barriers in the perspectives under uncertainties. Community uncertainty, policy and regulation problems, city architecture, and technology interaction are the factors that influence sustainable performance. In practices, (1) diverse disciplines and sectors in local, national, and global communities; (2) a lack of mobility and reliability; (3) mass production and mass consumption; (4) an insufficient level of artificial intelligence application; and (5) failures related to data management and security hinder the improvement of sustainable solid waste management toward society 5.0. The social and technical perspectives are indicated as the top priorities to improve SSWM performance.