[Radionuclide research on reparative bone formation during the treatment of spiral bone fractures of the leg by G. A. Ilizarov's method]. / Radionuklidnye issledovaniia reparativnogo kosteobrazovaniia pri lechenii vintoobraznykh perelomov kostei goleni po G. A. Ilizarovu.

A study was made of reparative osteogenesis and the content of mineral bone components in 60 patients with spiral fractures of the leg bones during treatment by transosseous osteosynthesis. The time of maximum labeled pyrophosphate accumulation was determined by a degree of the initial dislocation of fragments: in the dislocation to the cortical layer it was noted on the 42nd day, by 1/3 on the 45th day, by 2/3 on the 50th day, to the cross section on the 60th day. The demineralization of bone fragments in the dislocation to the cortical layer was 34%, by 1/2 37%, by 2/3 41% and to the cross section by 44%. The labeled sulphuric colloid accumulation by bone marrow cells was maximal in minimal dislocations and decreased with growing dislocation.

[Studies with 99mTc-pyrophosphate of reparative osteogenesis during treatment of closed oblique fractures of the long tubular bones]. / Issledovaniia s 99mTc-pirofosfatom reparativnogo kosteobrazovaniia pri lechenii zakrytykh kosykh perelomov dlinnykh trubchatykh kostei.

Altogether 56 patients aged 20-55 with closed oblique fractures of the upper and lower limb bones were observed. Reparative osteogenesis was studied using 99mTc-pyrophosphate. An elevated RP accumulation at the ends of the bone splinters was found from the 1st day after fracture. By the end of the 1st month after fracture the RP activity increased up to 750% in the absence of splinter dislocation. In dislocation it was 50-80% less. The RP maximal activity in the place of fracture was noted on the 7-8th week, in the dislocation of splinters on the 9-10th week. By the results of radionuclide studies, the fracture consolidated right after a decrease in the 99mTc-pyrophosphate accumulation that made it possible to determine the optimum time of bone consolidation.

[Radionuclide studies on healing in closed transverse fractures of the long tubular bones]. / Radionuklidnye issledovaniia zazhivleniia pri zakrytykh poperechnykh perelomakh dlinnykh trubchatykh kostei.

A total of 86 patients were examined by 99mTc-pyrophosphate in the course of therapy using the transosseous synthesis method. An elevated accumulation of the radiopharmaceutical was observed since the first day following a trauma. Maximum enhancement of metabolic processes in the absence of fragment displacement was noted on the 8th week and in the lack of displacement on the 9th-10th week. Then the intensity of bone formation got weaker. It was found appropriate that G. A. Ilizarov's apparatus should be removed exactly at that time. The content of mineral components in the regenerate was over 60% which demonstrated the bone ability to stand physiological loads.

[Radionuclide multicollector lymphography of the extremities]. / Radionuklidnaia mnogokollektornaia limfografiia konechnostei.

A study was made of the lymph flow rate and accumulation-absorption function of the inguinal and popliteal lymph nodes in healthy persons and in patients with leg and forearm bone fractures. The lymph flow rate in the leg of a healthy person is 9.1 = 10.8 cm/min, much more in the hip 13.7 = 16.1 cm/min, in the deep collector it was 2 = 3 times as less. The lymph flow rate in the forearm is equal 5.6 = 7.9 cm/min, in the shoulder 7.4 = 10.0 cm/min. After the fracture the lymph flow rate lessened for a short period of time (up to the 21 st day) in the vessels of the medial leg collector but increased in the lateral and deep collectors. In the upper limb the lymph flow rate decreased in the lateral and increased in the medial collectors.