ABSTRACT
No disponible
Subject(s)
Humans , Male , Adult , Methanol/poisoning , Alcoholism/complications , Renal Insufficiency, Chronic/etiology , Renal DialysisSubject(s)
Methanol/poisoning , Renal Dialysis/methods , Adult , Alcoholism/complications , Bicarbonates/therapeutic use , Ethanol/adverse effects , Ethanol/therapeutic use , Humans , Intubation, Intratracheal , Male , Methanol/blood , Perfume/adverse effects , Poisoning/therapy , Psychomotor Agitation/etiology , Respiration Disorders/chemically induced , Vision Disorders/chemically inducedABSTRACT
El Péptido Natriurético Atrial (PNA) ha sido estudiado en el tratamiento del fracaso renal agudo (FRA). Aunque algunos trabajos ofrecieron resultados alentadores dos estudios randomizados, multicéntricos, con un gran número de enfermos no obtuvieron diferencias frente a placebo. Últimamente dos artículos, con pequeño tamaño muestral han objetivado buenos resultados, pero dados los antecedentes sería recomendable la realización de estudios a mayor escala antes de poder extenderlo en el tratamiento del FRA. (Recomendación B.) La urodilatina también mostró resultados iniciales positivos, pero en un estudio con un mayor número de pacientes tampoco demostró superioridad respecto al placebo (Recomendación A.) La endotelina es una molécula vasoactiva muy importante a nivel renal. En fase experimental se han estudiado las acciones de varios fármacos que bloquean los receptores de la endotelina A o mixtos A/B. Hasta el momento no ha habido estudios en humanos que pudieran ser susceptibles de análisis. (Recomendación A.)
No disponible
Subject(s)
Humans , Acute Kidney Injury/prevention & control , Atrial Natriuretic Factor/pharmacokinetics , Endothelins/pharmacokineticsSubject(s)
Agrobacterium tumefaciens/isolation & purification , Catheters, Indwelling/microbiology , Gram-Negative Bacterial Infections/microbiology , Peritoneal Dialysis, Continuous Ambulatory/adverse effects , Peritonitis/microbiology , Anti-Bacterial Agents/therapeutic use , Gram-Negative Bacterial Infections/drug therapy , Humans , Kidney Failure, Chronic/therapy , Male , Middle Aged , Peritonitis/drug therapyABSTRACT
OBJECTIVE: To evaluate catheter-related complications among self-locating and other variants of Tenckhoff catheters. PATIENTS AND METHODS: We studied all self-locating catheters implanted in our hospitals from May/97 to Dec/05. We extended the follow-up to Jun/05. We collected demographic data, causes of catheter withdrawal and dropping of PD. We studied data about technique and catheter related complications. RESULTS: We included 328 catheters in 285 patients. There were 258 self-locating, 55 straight and 15 curled. There was a higher rate of catheter withdrawal due to malfunction in patients with straight or pig-tail catheters than in self-locating ones (log-rank, p < 0.001). CONCLUSION: In our patients, self-locating catheters have a lower malfunction rate than other variants of Tenckhoff catheters.
Subject(s)
Catheters, Indwelling/adverse effects , Peritoneal Dialysis/instrumentation , Adolescent , Adult , Aged , Aged, 80 and over , Device Removal , Equipment Design , Equipment Failure , Humans , Middle AgedABSTRACT
The Fanconi syndrome is an array of multiple proximal renal tubular dysfunctions occurring in association with several exogenous toxins, such as aminoglycosides. These antibiotics remain the drugs of choice in most gram-negative infections, but nephrotoxicity is the main drawback for them. Furthermore, the nephrotoxic effects may be overlooked with routine analyses. With the purpose of making physicians aware of this underrecognized complication, we are reporting here 3 cases of Fanconi's syndrome related to the administration of high-dose aminoglycosides (ranging from 3.6 to 15 g) with normal serum urea nitrogen and creatinine levels. The pattern of aminoaciduria demonstrated high increases in neutral amino acids, followed by dibasic and near-normal acidic amino acids. We also report the urinary excretion rates of total protein and beta2-microglobulin and protein electrophoresis results. We compared these cases with others reported in the literature.
