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J Coll Physicians Surg Pak ; 13(11): 644-8, 2003 Nov.
Article in English | MEDLINE | ID: mdl-14700492

ABSTRACT

OBJECTIVE: To evaluate the frequency of clinico-radiological presentation and the prognosis after treatment of chondroblastoma. DESIGN: A descriptive, observational study. PLACE AND DURATION OF STUDY: The study was carried out at the Department of Orthopaedic Surgery, JPMC, Karachi over the period of 16 years, January 1986 to June 2002. METHODOLOGY: Patients in teenage, presenting with signs and symptoms of a primary bone tumours, were included by retrospectively reviewing the tumour registry record. Detailed scrutiny of clinical record was carried out to analyze the clinico-radiological presentation and posttreatment prognosis criteria of healing was symptom-free centripetal and homogeneous ossification. RESULTS: Seven (1.24%) out of 563 primary bone tumour cases were chondroblastoma. The clinico-radiological presentation in the 2 out of 7 (28.57%) cases was classical, 2 simulated osteomyelitis and other 3 as chondromyxoid fibroma, aneurysmal bone cyst and giant cell tumour. Lesions were treated with curettage and bone grafting. One patient (14.28%) developed recurrence within 2 years after curettage and healed after re-curettage and bone grafting. Five out of 7 (71.42%) tumours showed good response and 2 out of 7 (28.57%) showed satisfactory response. CONCLUSION: Chondroblastoma is very rare benign primary bone tumour with high local recurrence rate. The lesions confined to epiphysis of weight-bearing bone present early with symptoms of mild arthritis. Lesions in non-weight-bearing bones often present late and simulates epiphysio-metaphyseal tumours. Lesions heals with centripetal healing and need more than 2 years follow-up to achieve recurrence-free healing.


Subject(s)
Bone Neoplasms/pathology , Bone Neoplasms/surgery , Chondroblastoma/pathology , Chondroblastoma/surgery , Neoplasm Recurrence, Local/epidemiology , Adolescent , Age Distribution , Biopsy, Needle , Bone Neoplasms/epidemiology , Bone Transplantation/methods , Chondroblastoma/epidemiology , Curettage/methods , Female , Humans , Male , Neoplasm Recurrence, Local/diagnostic imaging , Neoplasm Staging , Orthopedic Procedures/adverse effects , Orthopedic Procedures/methods , Pakistan/epidemiology , Prevalence , Prognosis , Radiography , Registries , Retrospective Studies , Risk Assessment , Sex Distribution , Time Factors
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