ABSTRACT
Oral stomatitis induced by endogenous progesterone is a rare clinical condition which may be associated with cutaneous involvement. That is probably due to the peak of progesterone production during the luteal phase of the menstrual cycle. In the present case report, a 21-year-old patient displayed recurrent ulcerative lesions located on the buccal mucosa or the upper lip, on a monthly basis since the age of 15. Such lesions would always manifest themselves on the second day until the end of the menstrual cycle.
Subject(s)
Progesterone/metabolism , Stomatitis/etiology , Cheek/pathology , Estrogen Antagonists/therapeutic use , Female , Humans , Lip/pathology , Luteal Phase , Menstrual Cycle/metabolism , Mucous Membrane/pathology , Stomatitis/drug therapy , Stomatitis/pathology , Tamoxifen/therapeutic use , Time Factors , Treatment Outcome , Young AdultABSTRACT
Lichen planus is a common mucocutaneous disease. However, lichen planus with concomitant oral and genital involvement is a rare condition that requires multidisciplinary intervention for appropriate diagnosis. In this study, we reported two cases of oro-genital lichen planus in a man and a woman. Analyses of oral and genital lesions were clinically and histopathologically compatible with lichen planus. This description highlights the importance of patients presenting oral lichen planus be routinely required to undergo further medical examination in order to investigate putative genital mucosal involvement. These lesions have the potential to progress to neoplasia. Therefore, medical and dentistry professionals should be aware of this condition.
