[Study of arteriosclerosis in different geographical zones of the Soviet Union. 3. Fatty acid composition of blood serum lipid fractions in Tashkent population]. / Izuchenie ateroskleroza v razlichnykh geograficheskikh zonakh Sovetskogo Soiuza. Soobshchenie III. Zhirnokislotnyi sostav lipidnykh fraktsii syvorotki krovi u zhitelei Tashkenta.

The composition of fatty acids in triglycerides and cholesterol ethers of blood serum was studied in 90 normal males, Russians and Uzbeks, aged 20 to 50 years, living in the city of Tashkent. The peculiarity of the tryglycerides fraction in indigenous Tashkent inhabitants consists in a high content of linoleic acid. (24.8%). This is attributed to the peculiarities of nutrition of the indigenous Uzbekistan population--a consumption of great amounts of cotton-seed oil rich in linoleic acid. With the growing age, the content of the linoleic acid in the cholesterol ethers decreases, and the portion of palmitic and oleic acids growing. Among indigenous. Tashkent residents, aged 20-29 years, the relative content of the linoleic acid in the cholesterol ether fraction is higher than among the non-indigenous residents of the same age-group.

[Study of arteriosclerosis in different geographical zones of the Soviet Union. II. The fatty acid makeup of the lipids of the vascular wall in inhabitants of Uzbekistan]. / Izuchenie ateroskleroza v razlichnykh geograficheskikh zonakh Sovetskogo Soiuza. Soobshchenie II. Zhirnokislotnyi sostav lipidov sosudistoi stenki u zhitelei Uzbekistana

A detailed description is presented for the fatty acids composition of the ether fractions of cholesterol, triglycerides and phospholipids in the normal aortic intima and at various stages of atherosclerosis in indigenous population (Uzbeks) and migrant (Russian) population of Uzbekistan. The most significant changes were revealed in the cholesterol ethers. At various stages of atherosclerosis the changes in the fatty acids of cholesterol ethers are not identical and depend on the nature of the lesion. The relative content of the oleic acid is usually higher, and that of the linoleic--lower in the fat strands and spots, than in the unchanged aortic intima. In the atheromatous plaques, on the contrary, the content of the linoleic acid increases, and that of the oleic--decreases. With age, the content of the linoleic acid increases even in the portions of the intima free of atherosclerosis. The relative content of linoleic acid in the triglycerides of the normai intima and in the atheromatous plaques is higher in the indigenous population of Uzbekistan, than in the migrants.