ABSTRACT
The results of personal experience of Althesin in long-duration (from 4 to 11 hours) neurosurgery are presented. The drug was used as an induction agent and for maintaining anaesthesia in continuous perfusion. Considering the good results obtained, the simplicity of the technique and the lack of side effects, it is concluded that Althesin is useful in this type of surgery, particular stress being laid on the speed and quality of arousal, and the excellent tolerance assessed by exploring secretory and excretory function of the liver with enzymatic tests.
Subject(s)
Alfaxalone Alfadolone Mixture , Anesthesia, Intravenous/methods , Neurosurgery , Adult , Aged , Drug Evaluation , Drug Tolerance , Female , Humans , Male , Middle Aged , Preanesthetic Medication , Time FactorsABSTRACT
Evaluation of Althesin in open eyeball surgery is reported. The anaesthetic gave surgically very useful and stable hypotonia, comparable with that offered by pentothal. Its is felt that steroid anaesthesia is excellent for surgical purposes and that Althesin is ideal on account of its overall features: lack of toxicity, high therapeutic index, tranquil induction, rapid return to consciousness, excellent quality, absence of carryover effects, and easy regulation. It is, moreover, rarely responsible for coughing and vomiting. It is preferable in eye surgery to "heavy" anaesthetics, such as barbiturates and volatile halogenates, particularly in the aged.
