ABSTRACT
We report two cases of idiopathic orbital myositis treated with radiation therapy (RT). Both patients visited our hospital with complaints of orbital pain on eye movement and eyelid swelling. There was no history of thyroid disease or trauma, and no signs of infection, neoplasm, or collagen disease. The laboratory investigations, including a thyroid function test, showed no abnormalities in either woman. They were initially treated with a combination of corticosteroids (CS) and nonsteroidal anti-inflammatory drugs (NSAIDs), however, they became dependent on or refractory to oral CS therapy, and received 20 Gy in 10 fractions of RT to the orbit. Their symptoms decreased immediately, and both patients were able to reduce the dosage of oral CS after RT. One patient could completely withdraw oral CS thereafter. However, they both experienced recurrence at eight months after RT, and have been receiving oral CS to control their symptoms. RT at doses of 20 Gy in 10 fractions for patients with idiopathic orbital myositis appears to be effective in palliating symptoms, but long-term control is not satisfactory.
Subject(s)
Orbital Pseudotumor/radiotherapy , Administration, Oral , Adrenal Cortex Hormones/administration & dosage , Adrenal Cortex Hormones/therapeutic use , Adult , Anti-Inflammatory Agents, Non-Steroidal/administration & dosage , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Female , Humans , Middle Aged , Orbital Pseudotumor/drug therapy , Palliative Care , Radiotherapy Dosage , RecurrenceABSTRACT
PURPOSE: A new version of frequency doubling perimetry was compared to a former version in patients with glaucoma. DESIGN: Prospective observational study. METHOD: Thirty-two patients with glaucoma were examined twice sequentially in one eye with threshold c-20 of frequency doubling perimetry version 2.6. Within 3 months, the same eye was again examined twice sequentially, this time using the new version 3.0. Mean deviation, pattern standard deviation, short-term fluctuation, intraocular pressure at examination, and test duration were compared between versions. RESULTS: No significant difference was found in mean deviation, pattern standard deviation, intraocular pressure, or short-term fluctuation between versions. CONCLUSIONS: Version 3.0 took less time to perform the threshold test than did version 2.6. Version 3.0 of the frequency doubling perimetry program took less time to perform and showed similar values of visual field indexes when compared with version 2.6.
Subject(s)
Glaucoma/diagnosis , Vision Disorders/diagnosis , Visual Field Tests/methods , Visual Fields , Adult , Aged , Female , Humans , Male , Middle Aged , Prospective Studies , SoftwareABSTRACT
PURPOSE: We studied the results obtained by repeated frequency doubling perimetry in patients with glaucoma and demonstrated a learning effect. METHODS: Prospective observational study. Thirty-three patients who had glaucoma and had never experienced frequency doubling perimetry participated in this study. The patients were examined by frequency doubling perimetry three times within 6 months. Mean deviation, pattern standard deviation, and intraocular pressure at examination were compared among three results. RESULTS: On frequency doubling perimetry, the mean deviation results of the first, second, and third tests were -7.96 dB, -7.29 dB, and -7.36 dB, respectively. The first and second results and the first and third results were significantly different (P = 0.029 and P = 0.049, respectively). No significant differences with regard to pattern standard deviation and intraocular pressure were noted. CONCLUSION: A positive learning effect was found for frequency doubling perimetry in the first and second mean deviation results of patients with glaucoma.
