ABSTRACT
Hantavirus cardiopulmonary syndrome is characterized by pulmonary capillary leakage and alveolar flooding, resulting in 50% mortality due to fulminant hypoxic respiratory failure. In addition, depression of cardiac function ensues, which complicates the picture with cardiogenic shock. Early diagnosis and appropriate use of extracorporeal membrane oxygenation (ECMO) are amongst the lifesaving interventions in this fatal illness. However, a recent case report demonstrates that implementation of high volume continuous hemofilteration along with protective ventilation reverses the cardiogenic shock within few hours in hantavirus infected patients. This review article is focused on the recent advances in clinical features, diagnosis, management, epidemiology, and pathogenesis of hantavirus induced cardiopulmonary syndrome. It provides information for clinicians to help in correct diagnosis during the early stages of viral infection that could improve the prognosis of this viral illness.
Subject(s)
Hantavirus Infections/complications , Hantavirus Pulmonary Syndrome/diagnosis , Hantavirus Pulmonary Syndrome/pathology , Shock, Cardiogenic/diagnosis , Shock, Cardiogenic/pathology , Disease Management , Early Diagnosis , Extracorporeal Membrane Oxygenation , Hantavirus Pulmonary Syndrome/mortality , Hantavirus Pulmonary Syndrome/therapy , Hemofiltration , Humans , Respiration, Artificial , Shock, Cardiogenic/mortality , Shock, Cardiogenic/therapy , Treatment OutcomeSubject(s)
Dementia/therapy , Nutritional Support , Culture , Gastrostomy , Humans , Nutritional Status , Quality of LifeABSTRACT
Hantaviruses affect people worldwide, yet they remain poorly understood. This article explores the known history of hantaviruses. It describes diagnostic methods and potential options for treatment and prevention.
