La contribución del farmacéutico clínico a la atención del paciente en Urgencias / Contribution of clinical pharmacists to patient’s care in the Emergency Department

No disponible

Presentación clínica, actitud terapéutica y evolución de las intoxicaciones agudas tratadas con carbón activado: ¿existen diferencias entre hombres y mujeres? / Clinical presentation, therapeutic approach and outcomes in acute poisoning treated with activated charcoal. Are there differences between men and women?

Objetivo. Determinar las posibles diferencias entre hombres y mujeres en la forma de presentación clínica, en la actitud terapéutica y en la evolución de las intoxicaciones agudas tratadas con carbón activado. Método. Estudio descriptivo realizado en el Servicio de Urgencias del Hospital Clínic de Barcelona durante los años 2001 y 2008. Se incluyeron pacientes intoxicados que habían recibido carbón activado. Se incluyeron variables epidemiológicas, de presentación clínica, toxicológicas, de abordaje terapéutico, tiempos asistenciales y evolución. Resultados. Se han incluido 575 pacientes. La media de edad fue de 37,8 (DE 14,8) años y el 65,7% fueron mujeres. No se han observado diferencias entre hombres y mujeres respecto a la edad, número de principios activos implicados en la intoxicación o número de pastillas ingeridas, pero se observó una mayor prevalencia de intoxicación benzodiacepínica en las mujeres respecto a los hombres (69,8 frente a 61,2%; p<0,05). El etanol como acompañante de la intoxicación medicamentosa fue más frecuente en hombres que en mujeres (32,4 frente a 18,8%; p<0,001). El uso del carbón en las intoxicaciones no medicamentosas fue también más frecuente en hombres que en mujeres (7,9 frente a 3,2%; p<0,05). No hubo diferencias entre sexos respecto a las manifestaciones clínicas de la intoxicación, los tiempos de demora asistencial, las horas de estancia, el tratamiento y la evolución. Conclusiones. La intoxicación por benzodiacepinas fue más prevalente en mujeres que en hombres. Las intoxicaciones no-medicamentosas y la toma de bebidas alcohólicas con la ingesta medicamentosa fueron más frecuentes en hombres. Las repercusiones clínicas de estas intoxicaciones, la demora asistencial, las necesidades terapéuticas y de ingreso fueron iguales en ambos sexos (AU)

Objective. To determine whether there are gender-based differences in the clinical presentation, therapeutic approaches and outcomes in acute poisoning treated with activated charcoal. Method. A descriptive study conducted in the Emergency Department of the Hospital Clínic de Barcelona over the 7 years between the years 2001 and 2008. The study included poisoned patients who had received activated charcoal. The variables included, epidemiological data, clinical and toxicological presentation, therapeutic approach, time in emergency department and outcomes. Results. A total of 575 patients were included in the study. The mean age was 37.8 (SD 14.8) years and 65.7% were females. No differences were observed between males and females with respect to age, number of drugs involved in the poisoning or the number of tablets ingested, but a higher prevalence of benzodiazepine poisoning was observed in females compared to males (69.8 vs. 61.2%; P<0.05). Alcohol combined with drug poisoning was more common in males than in females (32.4 vs.18.8%; P<0.001). Administration of activated charcoal in non-drug poisoning was also more common in males than in females (7.9 vs. 3.2%; P<0.05). There were no differences between genders as regards clinical presentation of the poisonings, delays in care, hours of emergency department stay, treatment or outcome. Conclusions. Benzodiazepine poisoning was more prevalent in females than in males. Non-drug poisonings and alcohol combined with drug ingestion were more common in males. The clinical outcomes of the poisonings, delays in care, therapeutic requirements and admissions were similar between genders (AU)

[Clinical presentation, therapeutic approach and outcomes in acute poisoning treated with activated charcoal. Are there differences between men and women?]. / Presentación clínica, actitud terapéutica y evolución de las intoxicaciones agudas tratadas con carbón activado: ¿existen diferencias entre hombres y mujeres?

OBJECTIVE: To determine whether there are gender-based differences in the clinical presentation, therapeutic approaches and outcomes in acute poisoning treated with activated charcoal. METHOD: A descriptive study conducted in the Emergency Department of the Hospital Clínic de Barcelona over the 7 years between the years 2001 and 2008. The study included poisoned patients who had received activated charcoal. The variables included, epidemiological data, clinical and toxicological presentation, therapeutic approach, time in emergency department and outcomes. RESULTS: A total of 575 patients were included in the study. The mean age was 37.8 (SD 14.8) years and 65.7% were females. No differences were observed between males and females with respect to age, number of drugs involved in the poisoning or the number of tablets ingested, but a higher prevalence of benzodiazepine poisoning was observed in females compared to males (69.8 vs. 61.2%; P<0.05). Alcohol combined with drug poisoning was more common in males than in females (32.4 vs.18.8%; P<0.001). Administration of activated charcoal in non-drug poisoning was also more common in males than in females (7.9 vs. 3.2%; P<0.05). There were no differences between genders as regards clinical presentation of the poisonings, delays in care, hours of emergency department stay, treatment or outcome. CONCLUSIONS: Benzodiazepine poisoning was more prevalent in females than in males. Non-drug poisonings and alcohol combined with drug ingestion were more common in males. The clinical outcomes of the poisonings, delays in care, therapeutic requirements and admissions were similar between genders.

Consumo oculto de cocaína en urgencias neurológicas / No disponible

No disponible