ABSTRACT
Melioidosis was first recognized in northeastern Brazil in 2003. Confirmation of additional cases from the 2003 cluster in Ceará, more recent cases in other districts, environmental isolation of Burkholderia pseudomallei, molecular confirmation and typing results, and positive serosurveillance specimens indicate that melioidosis is more widespread in northeastern Brazil than previously thought.
Subject(s)
Burkholderia pseudomallei/pathogenicity , Communicable Diseases, Emerging/epidemiology , Disease Outbreaks , Melioidosis/epidemiology , Adolescent , Brazil/epidemiology , Burkholderia pseudomallei/isolation & purification , Child , Communicable Diseases, Emerging/mortality , Communicable Diseases, Emerging/physiopathology , Electrophoresis, Gel, Pulsed-Field , Female , Humans , Male , Melioidosis/mortality , Melioidosis/physiopathologyABSTRACT
Burkholderia pseudomallei has rarely been isolated from environmental and clinical specimens in South America, particularly, in Brazil. This report describes a case of melioidosis with fulminant sepsis in a 10 year old boy, from rural area, in Tejuçuoca, State of Ceará, Brazil. Blood samples were positive and, through the analysis of results from biochemical tests and of drugs susceptibility profile, identified this gram-negative bacillus as B. pseudomallei. The contamination source remains obscure in this case, as soil and water tanks samples submitted to microbiological analyses did not indicate the presence of B. pseudomallei.
Subject(s)
Burkholderia pseudomallei/isolation & purification , Melioidosis/diagnosis , Brazil , Burkholderia pseudomallei/drug effects , Child , Fatal Outcome , Humans , Male , Microbial Sensitivity TestsABSTRACT
O isolamento de Burkholderia pseudomallei, de meio ambiente e de espécimes clínicos, foi raramente registrado na América do Sul, particularmente no Brasil. Este relato descreve o caso de melioidose em um paciente de 10 anos de idade, de área rural do estado do Ceará (Tejuçuoca). As hemoculturas foram positivas e as análises dos testes bioquímicos e de susceptibilidade aos antimicrobianos do isolado foram indicativos para a identificação de B. pseudomallei. A fonte de contaminação foi obscura, uma vez que as análises microbiológicas de solo e água no tanque foram negativas.
