ABSTRACT
BACKGROUND: A randomized, prospective, double-blinded clinical study was conducted at a single, tertiary referral center. The aim of the study was to evaluate the effects of nasal decongestant use in the early postoperative period after septoplasty. METHODS: After septoplasty, patients who met the study inclusion criteria were randomized into 2 groups to receive either physiologic saline irrigation (saline group) or physiologic saline irrigation plus oxymetazoline hydrochloride 0.05% nasal spray (saline+oxymetazoline group). Visual analog scale (VAS) scores for bleeding, pain, and nasal crusting; Nasal Obstruction Symptom Evaluation (NOSE) scores; and rhinomanometric measurements were assessed pre- and postoperatively. RESULTS: The VAS scores for bleeding and nasal crusting of patients in the saline+oxymetazoline group were significantly lower compared with the saline group (p < 0.005). VAS scores for pain were similar between the groups (p > 0.05). Total nasal resistance and NOSE scores of patients in the saline+oxymetazoline group were significantly lower than in saline group after surgery (p < 0.005). CONCLUSION: The use of nasal decongestant sprays in the very early postoperative period is beneficial to reduce the postsurgical nasal crusting and bleeding symptoms and also for decreasing nasal resistance in this edematous period.
Subject(s)
Hemorrhage/prevention & control , Nasal Decongestants/therapeutic use , Nasal Obstruction/drug therapy , Nasal Septum/surgery , Oxymetazoline/therapeutic use , Plastic Surgery Procedures , Postoperative Complications/prevention & control , Adult , Double-Blind Method , Female , Hemorrhage/etiology , Humans , Male , Middle Aged , Nasal Obstruction/surgery , Nasal Sprays , Postoperative Period , Treatment Outcome , Young AdultABSTRACT
Abstract Introduction: A considerable high number of SNHL patients also suffer from dizziness and related vestibular symptoms. Objective: To evaluate the association of vestibular dysfunction and sensorineural hearing loss (SNHL) in adult patients. Methods: Prospective, double-blinded, controlled studies composed by 63 adult patients without any vestibular symptoms or diagnosed vestibular diseases. Audiological status was measured with pure tone audiometry and the vestibular system was tested with vestibular evoked myogenic potential (VEMP). Patients were divided into two groups: a study group (patients with SNHL) and a control group (patients without SNHL). VEMP results of the groups were calculated and compared. Results: Mean P1 (23.54) and N1 (30.70) latencies were prolonged in the study group (p < 0.001) and the amplitudes of the study group were significantly reduced (p < 0.001). Both parameters of the VEMP test were abnormal in the study group when compared to the control group. Conclusions: These findings suggest that age-related SNHL may be accompanied by vestibular weakness without any possible predisposing factors for vestibulopathy.
Resumo Introdução: Um número considerável de pacientes com PANS também sofre de tonturas e sintomas vestibulares relacionados. Objetivo: Avaliar a associação entre disfunção vestibular e perda auditiva neurossensorial (PANS) em pacientes adultos. Método: Estudo prospectivo, duplo-cego e controlado com 63 pacientes adultos, sem quaisquer sintomas vestibulares ou doença vestibular diagnosticada. A audição foi avaliada por meio de audiometria tonal e o sistema vestibular, com potenciais evocados miogênicos vestibulares (PEMV). Os pacientes foram divididos em dois grupos: grupo de estudo (pacientes com PANS) e grupo de controle (pacientes sem PANS). Os resultados dos PEMV dos grupos foram calculados e comparados. Resultados: As latências médias de P1 (23,54) e N1 (30,70) encontravam-se prolongadas no grupo de estudo (p < 0,001), e as amplitudes no grupo de estudo estavam significantemente reduzidas (p < 0,001). Ambos os parâmetros do teste de PEMV foram anormais no grupo de estudo quando comparados aos do grupo controle. Conclusões: Nossas achados sugerem que a PANS relacionada à idade pode ser acompanhada por hipofunção vestibular, mesmo na ausência de possíveis fatores predisponentes para vestibulopatia.
Subject(s)
Humans , Male , Female , Middle Aged , Aged , Aged, 80 and over , Presbycusis/complications , Vestibular Diseases/complications , Presbycusis/diagnosis , Reaction Time , Audiometry, Pure-Tone , Case-Control Studies , Vestibular Diseases/diagnosis , Double-Blind Method , Prospective StudiesABSTRACT
INTRODUCTION: A considerable high number of SNHL patients also suffer from dizziness and related vestibular symptoms. OBJECTIVE: To evaluate the association of vestibular dysfunction and sensorineural hearing loss (SNHL) in adult patients. METHODS: Prospective, double-blinded, controlled studies composed by 63 adult patients without any vestibular symptoms or diagnosed vestibular diseases. Audiological status was measured with pure tone audiometry and the vestibular system was tested with vestibular evoked myogenic potential (VEMP). Patients were divided into two groups: a study group (patients with SNHL) and a control group (patients without SNHL). VEMP results of the groups were calculated and compared. RESULTS: Mean P1 (23.54) and N1 (30.70) latencies were prolonged in the study group (p<0.001) and the amplitudes of the study group were significantly reduced (p<0.001). Both parameters of the VEMP test were abnormal in the study group when compared to the control group. CONCLUSIONS: These findings suggest that age-related SNHL may be accompanied by vestibular weakness without any possible predisposing factors for vestibulopathy.
