[Clinico-immunological characteristics of people who worked within the 30-kilometer zone of the accident at the Chernobyl Atomic Power Plant 4 years after the accident]. / Kliniko-immunologicheskaia kharakteristika kontingenta lits, rabotavshikh v 30-kilometrovoi zone avarii na Chernobyl'skoi AES cherez 4 goda posle radiatsionnoi avarii.

Clinical examination with immune status assessment of more than 300 healthy persons, who worked in 30-km Chernobyl NPP zone four years after the accident was carried out. The clinical characters of immune deficiency were detected in 6.67% of examined persons and appeared as repeated respiratory diseases. Significant increase in mean level of leukocytes and lymphocytes was revealed. Activation of T-helper link of cell immunity was determined by increase of CD4+ cells in 35.2% of examined persons, that were lower than in people who took part in Chernobyl accident amelioration in 1986. Decrease in content of T-cells and B-cells was observed in 1/4 and 3/4 of persons correspondingly by rosette assays. No changes in serum immunoglobulins level was observed.

[Influence of iodine preparations and triiodothyronine on the histological structure of the thyroid gland in experimental goiter]. / Vliianie iodistykh preparatov i triiodtironina na gistologicheskuiu strukturu shchitovidnoi zhelezy pri eksperimental'nom zobe

Histological changes in the thyroid gland of rats in experimental goiter caused by administration of 6-methylthiouracil during 9 months, as well as changes in the structure of these glands under the effect of diurnal ingestion with food of microiodine (iodized potassium 2 mg+iodine 0.2 mg per animal), diiodotyrosine (1.25 mg per animal) and triiodthyronine (5 mcg per animal) are described. As a result of the exposure to the above mentioned preparations, there were noted a decrease in the weight of the thyroid glands reduction in the number and size of microadenoms therein, a drop of the intensity of hyperplastic processes in the thyroid epithelium, and an increased proliferation of clear cells. The greatest effect was observed in the animals which received triiodothyronine: weight and histological structure of the glands in these animals was approximating the norm. There were revealed anaplastic changes in the microadenomas remained after the exposure to iodine preparations and triiodothyronine, and an increased proliferation of clear cells with formation of microadenoms out of them.