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1.
Sci Rep ; 11(1): 14236, 2021 Jul 09.
Article in English | MEDLINE | ID: mdl-34244596

ABSTRACT

In this paper, we present the approach to complete Bell state analysis based on filtering mapping. The key distinctive feature of this appoach is that it avoids complications related to using either hyperentanglement or representation of the Bell states as concatenated Greenber-Horne-Zeilinger (C-GHZ) state to perform discrimination procedure. We describe two techniques developed within the suggested approach and based on two-step algorithms with two different types of filtration mapping which can be called the non-demolition and semi-demolition filtrations. In the method involving non-demolition filtration measurement the filtration process employs cross-Kerr nonlinearity and the probe mode to distinguish between the two pairs of the Bell states. In the case of semi-demolition measurement, the two states are unambiguously discriminated and hence destroyed, whereas filtraton keeps the other two states intact. We show that the measurement that destroys the single photon subspace in every mode and preserves the superposition of zero and two photons can be realized with discrete photodetection based on microresonator with atoms.

2.
Opt Express ; 27(25): 36551-36561, 2019 Dec 09.
Article in English | MEDLINE | ID: mdl-31873431

ABSTRACT

In this paper we propose feasibility demonstration of twin-field quantum key ditribution system based on multi-mode weak coherent phase-coded states. Their utilization provides indisputable advantages described in the paper. We also provide the detailed description of nontrivial interference scheme for those states and derive detection and quantum bit error rates. Since we propose the feasibility scheme we present in this paper only asymptotic secure key estimation and show that in principle it can beat well-known fundamental limit of repeaterless quantum communications , i.e., the secret key capacity of the lossy communication channel. Also we present here the experimental setup and provide the experimental values of detection rates dependence on the modulation signals phase difference.

3.
Opt Express ; 26(9): 11292-11308, 2018 Apr 30.
Article in English | MEDLINE | ID: mdl-29716053

ABSTRACT

We consider a subcarrier wave quantum key distribution (QKD) system, where quantum encoding is carried out at weak sidebands generated around a coherent optical beam as a result of electro-optical phase modulation. We study security of two protocols, B92 and BB84, against one of the most powerful attacks for this class of systems, the collective beam-splitting attack. Our analysis includes the case of high modulation index, where the sidebands are essentially multimode. We demonstrate numerically and experimentally that a subcarrier wave QKD system with realistic parameters is capable of distributing cryptographic keys over large distances in presence of collective attacks. We also show that BB84 protocol modification with discrimination of only one state in each basis performs not worse than the original BB84 protocol in this class of QKD systems, thus significantly simplifying the development of cryptographic networks using the considered QKD technique.

4.
Fiziol Cheloveka ; 41(6): 119-27, 2015.
Article in Russian | MEDLINE | ID: mdl-26859996

ABSTRACT

The article presents data on new approaches to the application of the surface electromyogram based on the nonlinear dynamics of complex systems. Special focus is placed on applicability of nonlinear parameters for early and differential diagnostics of Parkinson's disease, various kinds of tremor, schizophrenia, as well as for the estimation of normal processes in the motor system, such as musle development, fatigue and ageing.


Subject(s)
Diagnosis, Differential , Electromyography/methods , Parkinson Disease/diagnosis , Tremor/diagnosis , Aging/pathology , Humans , Nonlinear Dynamics , Parkinson Disease/physiopathology , Schizophrenia/diagnosis , Schizophrenia/physiopathology , Tremor/physiopathology
5.
Article in English | MEDLINE | ID: mdl-25570683

ABSTRACT

Deep brain stimulation (DBS) is an effective treatment method for motor symptoms of advanced Parkinson's disease. DBS-electrode is implanted to subthalamic nucleus to give precisely allocated electrical stimuli to brain. The optimal stimulus type has to be adjusted individually. Disease severity, main symptoms and biological factors play a role in correctly setting up the device. Currently there are no objective methods to assess the efficacy of DBS, hence the adjustment is based solely on clinical assessment. In optimal case an objectively measurable feature would point the right settings of DBS. Surface electromyographic and kinematic measurements have been used in Parkinson's disease research. As Parkinson's disease symptoms are known to change the EMG signal properties, these methods could be helpful aid in the clinical adjustment of DBS. In this study, 13 patients with advanced Parkinson's disease who received DBS treatment were measured. The patients were measured with seven different settings of the DBS in clinical range including changes in stimulation amplitude, frequency and pulse width. The EMG analysis was based on parameters that characterize EMG signal morphology. Correlation dimension and recurrence rate made the most significant difference in relation to optimal settings. In conclusion, EMG analysis is able to detect differences between the DBS setups, and can help in finding the correct parameters.


Subject(s)
Deep Brain Stimulation , Electromyography , Parkinson Disease/therapy , Aged , Electrodes , Female , Humans , Middle Aged , Parkinson Disease/pathology , Severity of Illness Index
6.
Vestn Ross Akad Med Nauk ; (4): 38-42, 1993.
Article in Russian | MEDLINE | ID: mdl-7687484

ABSTRACT

A total of 97 patients with pancreatic carcinoma were examined with sonography, computed tomography of the pancreas and endoscopy of the stomach and duodenum. The tumor involved mainly the head of the pancreas in 69 (71.1%), the body in 21 (21.7%) and the tail in 7 (7.2%) patients. Two basic types of the disease were identified: disseminated in 83 patients and rare in 14 patients. The disseminated type included a central (45 patients) and a peripheral (38 patients) variant. The latter is classed as peripheral (n = 30) and paraduodenal (n = 8). The rare types included masked variants (n = 6), miniblastomas (n = 3), megablastomas (n = 2) of the pancreas, as well as thrombotic variants of the disease (n = 3). The highest diagnostic value of sonography and computed tomography was observed in intrinsic peripheral variants of carcinoma. Gastroduodenal endoscopy along with biopsy of suspected segments is highly diagnostic in paraduodenal variants of the disease.


Subject(s)
Carcinoma/diagnosis , Pancreatic Neoplasms/diagnosis , Biopsy, Needle , Cholangiopancreatography, Endoscopic Retrograde , Diagnosis, Differential , Endoscopy, Digestive System , Humans , Pancreas/diagnostic imaging , Pancreas/pathology , Tomography, X-Ray Computed , Ultrasonography
8.
Klin Khir (1962) ; (9): 27-9, 1991.
Article in Russian | MEDLINE | ID: mdl-1766170

ABSTRACT

In analysis of clinical manifestations and results of surgical treatment of acute destructive cholecystitis in 215 elderly and senile patients, the authors established, that clinical picture of the given pathology was obscure, despite the presence of destructive forms of inflammation. The necessity for early performance of an operation is substantiated.


Subject(s)
Cholecystitis/surgery , Acute Disease , Aged , Aged, 80 and over , Cholecystitis/complications , Humans , Middle Aged , Time Factors
10.
Genetika ; 22(10): 2500-4, 1986 Oct.
Article in Russian | MEDLINE | ID: mdl-3539700

ABSTRACT

Nuclear DNAs of three forms of Microtus juldashi--M. carruthersi (group 1) and of three subspecies of polytypic species Alticola macrotis (group 2) were compared. Intensive interpopulational karyotype differentiation was observed in both groups, particularly, for centromeric heterochromatin quantity and localization. As satellite DNAs (satDNAs) were present in C-heterochromatin of the Rodents groups studied, the latter were used as a model for comparison of the satDNAs in the species in statu nascendi. With this view, the nuclear DNAs were studied by means of the neutral CsCl equilibrium centrifugation. In both groups examined, no correlation was found between the presence, the characteristics of the satDNAs and morphological as well as cytogenetic features of the animals. These results are an indirect confirmation of the idea, according to which satDNA does not possibly play significant role in the development of the reproductive isolation and species formation.


Subject(s)
Arvicolinae/genetics , DNA, Satellite/genetics , Genetic Variation , Animals , Species Specificity
15.
Mol Biol (Mosk) ; 12(6): 1348-58, 1978.
Article in Russian | MEDLINE | ID: mdl-745607

ABSTRACT

In order to elucidate the possible relationship between the karyotype and the polynucleotide sequence organization in DNA, comparison was made between DNA from the liver of Dicrostonyx torquatus chionapaes Allen with different numbers of B-chromosomes (2n = 47-49, 1-3 B-chromosomes; 2n = 52-54,6-8 B-chromosomes). The reassociation kinetics patterns for denatured DNA fragments (about 300 nucleotides long) were obtained by the batch hydroxyapatite method. The analysis of these patterns showed a approximately 10% increase in the proportion of reiterated nucleotide sequences in the DNA of animals with 6-8 B-chromosomes. The increase in the proportion of reiterations in DNA correlated with increase in the number of B-chromosomes can be regarded as an indirect confirmation of the heterochromatic nature of B-chromosomes. The individual fractions of reiterated nucleotide sequences (C0t = 1.0) were isolated from studied DNas. The reassociation kinetics of these fractions and the thermostability of resulting duplexes were examined. The revealed differences are indicative of a certain dissimilarity in the polynucleotide sequences organization that correlate with variation in the number of B-chromosomes. The heterochromatic and euchromatic. DNAas from the liver cell nuclei of animals carrying different numbers of B-chromosomes were studied by thermal denaturation analysis and neutral CsCl equilibrium centrifugation. In the heterochromatic DNAs from livers of D. t. chionopaes with 6-8 B-chromosomes additional components enriched with AT-pairs were revealed. The specific features of DNA correlated with increase in the number of B-chromosomes are discussed in connection with peculiarities of B-chromosomes behaviour and their evolution in Dicrostonyx torquatus chionapaes.


Subject(s)
Chromosomes/analysis , DNA , Animals , Kinetics , Liver/analysis , Nucleic Acid Denaturation , Nucleic Acid Renaturation , Rodentia
18.
Mol Biol (Mosk) ; 9(4): 548-51, 1975.
Article in Russian | MEDLINE | ID: mdl-765772

ABSTRACT

The results of a comparative analysis of the kinetic curves of reassociation of DNA of closely related species of Microtus (Microtus arvalis, Microtus oeconomus oeconomus, Microtus oeconomus Chachlovi) are presented. A five power polynomial was used as a mathematical model of the kinetic DNA reassociation curves. The values of polynomial coefficients and the theoretical value, both with statistical deviations dispersion, have been estimated with the help of a standard computer programme. The modified Fischer criterium was used for comparing the model kinetic curves of reassociation of the above species and of subspecies of Microtus, and to estimate the significance of the difference between two random means. A pair-wise comparison of the model curves shows that the similarity of the DNA polynucleotide sequences in two subspecies is less expressed than in two species of Microtus. A method of comparison of DNA nucleotide sequences is suggested on the basis of mathematical models of kinetic curves of DNA reassociation.


Subject(s)
DNA , Animals , Arvicolinae , Base Sequence , Computers , Kinetics , Nucleic Acid Denaturation , Polynucleotides , Species Specificity
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