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1.
CMAJ ; 150(3): 325; author reply 326, 1994 Feb 01.
Article in English | MEDLINE | ID: mdl-8293369
2.
Intensive Care Med ; 5(2): 69-71, 1979 May.
Article in English | MEDLINE | ID: mdl-458036

ABSTRACT

Antipyrine kinetics were studied in 12 critically ill patients. Antipyrine half life was found to be short (6.5 +/- 3.4 h), this did not alter over 4 days of acute illness, although there was a tendency for antipyrine clearance to decrease over that time period. The need for further pharmacological studies in critically ill patients is stressed.


Subject(s)
Antipyrine/metabolism , Adult , Antipyrine/pharmacology , Critical Care , Female , Half-Life , Humans , Infections/metabolism , Kidney/metabolism , Kinetics , Male , Middle Aged
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