[Rate of free radical peroxidation of lipids, activity of adenylate cyclase and permeability of plasma membrane for Ca2+ ions in cells of peripheral blood of sheep exposed to low-level radiation].

Chronic exposure of sheep at doses 0.1 and 0.5 Gy resulted in reduced contents of malondialdehyde, of diene and of triene conjugates and alpha-tocopherol with simultaneous increase in the retinol level in blood plasma. In lymphocytes of peripheral blood, the activity of adenylate cyclase was decreased, and in thrombocytes the phase pattern of changes was marked. The enzyme activity in blood cells stimulated by forskolin and prostaglandid E1 was more pronounced. The estimation of the plasma membrane permeability for Ca2+ ions in peripheral blood neutrophils has revealed nonlinear pattern of variations. Erythrocytes the showed increase in passive permeability of plasma membrane for Ca2+ ions.

[Evaluation of cell membrane permeability for Ca2+ and adenylate cyclase in sheep peripheral blood cells, exposed to low doses of radiation]. / Otsenka pronitsaemosti plazmaticheskoi membrany dlia Ca2+ i aktivnosti adenilattsiklazy v kletkakh perifericheskoi krovi ovets, obluchennykh v malykh dozakh.

Chronic irradiation of sheep with doses of 2.6 and 12.9 mC.kg was characterized by the modification of the adenylatecyclase activity and Ca2+ permeability of plasma membrane in cells of the peripheric blood, with no changes in the clinical and hematological indicators. The observed effects are assumed to result from structural and dynamic variations in the lipids of membranes.

[Diagnosis and treatment of tuberculous peritonitis]. / Diagnostika i lechenie tuberkuleznogo peritonita.

Basing on 73 cases, the experience in diagnosis and treatment of tuberculous peritonitis (TP) has been summarized. The analysis of principal clinical symptoms was carried out, diagnostic value of various methods of examination in TP was shown. It was established, that in majority of cases conservative therapy with application of antituberculous preparations contributed to improvement of patients' condition. In 31 patients suppuration of peritoneal liquid as well as bowel obstruction nesessitated urgent surgical intervention.

[Assessment of lipid peroxidation and plasma membrane permeability for Ca2+ in the red blood cells of cattle after the long term grazing on radioactively contaminated territory]. / Otsenka perikisnogo okisleniia lipidov i pronitsaemosti plazmaticheskoi membrany dlia Ca2+ v éritrotsitakh krovi krupnogo rogatogo skota pri dlitel'nom nakhozhdenii na radioaktivno zagriaznennykh territoriiak

Ten years after the Chernobyl accident a physiological condition of cows was examined on radioactivy contaminated territory of the Novozibkov district of the Bryansk region. The long grazing of cattle on radioactivly contaminated territory revealed the increase in permeability of plasmatic membrane of the red blood cells to Ca2+ and the activation of process of lipid peroxidation. The sensitivity of the red blood cells of cows to incubations in hypertonic conditions was demonstrated.

[Changes in the intensity of lipid peroxidation in the blood plasma of sheep under repeat gamma irradiation after chronic gamma exposure]. / Izmenenie intensivnosti perekisnogo okisleniia lipidov v plazme krovi ovets pri povtornom gamma-obluchenii posle khronicheskogo gamma-vozdeistviia.

The indices of lipid peroxidation and the contents of alpha-tocopherol and retinol in the blood plasma of sheep exposed to repeated gamma irradiations were studied. It was shown that a repeated acute gamma irradiation of sheep with sublethal and lethal doses after 9 months of chronic low-dose gamma irradiation adversely affected the activity of the lipid free-radical oxidation. A radiologic pathology in the repeatedly irradiated animals developed as a decrease in the intensity of spontaneous chemiluminescence. Also, a tendency to an increase in the concentration of malonic dialdehyde was observed along with weak changes in the contents of triene and diene conjugates and the levels of alpha-tocopherol and retinol.

[The estimate of the free-radical lipid oxidative indices of the blood plasma in irradiated sheep]. / Otsenka pokazatelei svobodnoradikal'nogo okisleniia lipidov v plazme krovi obluchennykh ovets.

External alpha-irradiation of sheep with doses of 51.6 and 154.8 mC/kg initiated free-radical oxidation of lipids in blood plasma, which was characterized by increase of spontaneous chemiluminescence intensity, malonaldehyde, conjugated diene and triene as well as of alpha-tocopherol concentration, while retinol level simultaneously decreased. On the contrary, chronic irradiation of sheep with doses of 2.58 and 12.9 mC/kg resulted in decrease of malonaldehyde content, conjugated diene and triene level as well as natural antioxidant alpha-tocopherol level in blood plasma.