1.
Am J Med Sci
; 290(4): 155-8, 1985 Oct.
Article
in English
| MEDLINE
| ID: mdl-2866712
ABSTRACT
Metastatic malignant pheochromocytoma can be a disease of long duration and though poorly responsive to both radiation therapy and chemotherapy, pharmacologic management of its myriad manifestations can be very effective. Hypertension is the most recognized feature of this disease, but gastrointestinal manifestations can, on rare occasions, be just as serious and life threatening. We present two patients with metastatic pheochromocytoma who developed pseudo-obstruction, and discuss the pathopharmacology and treatment of this syndrome.
Subject(s)
Adrenal Gland Neoplasms , Intestinal Obstruction/etiology , Intestinal Pseudo-Obstruction/etiology , Pheochromocytoma/secondary , Adrenal Gland Neoplasms/metabolism , Adrenergic alpha-Antagonists/therapeutic use , Adrenergic beta-Antagonists/therapeutic use , Adult , Catecholamines/metabolism , Constipation/drug therapy , Constipation/etiology , Fecal Impaction/etiology , Female , Humans , Intestinal Pseudo-Obstruction/drug therapy , Male , Pheochromocytoma/complications , Pheochromocytoma/metabolism
2.
JAMA
; 222(4): 457-9, 1972 Oct.
Article
in English
| MEDLINE
| ID: mdl-4677832
Subject(s)
Hypertension, Malignant/etiology , Renal Artery Obstruction/complications , Adult , Angiography , Humans , Hyperaldosteronism/diagnosis , Kidney/blood supply , Kidney/diagnostic imaging , Kidney Concentrating Ability , Kidney Function Tests , Male , Nephrectomy , Renal Artery Obstruction/surgery , Renin/metabolism
3.
Clin Pharmacol Ther
; 12(5): 843-8, 1971.
Article
in English
| MEDLINE
| ID: mdl-4936150
Subject(s)
Hydrochlorothiazide/therapeutic use , Hypertension/drug therapy , Quinazolines/therapeutic use , Adult , Aspartate Aminotransferases/blood , Blood Glucose/analysis , Blood Pressure/drug effects , Blood Urea Nitrogen , Carbon Dioxide/blood , Chlorides/blood , Clinical Trials as Topic , Female , Humans , Ketones/therapeutic use , Male , Methods , Placebos , Potassium/blood , Sodium/blood , Sulfonamides/therapeutic use , Uric Acid/blood
4.
Br Med J
; 4(5731): 347, 1970 Nov 07.
Article
in English
| MEDLINE
| ID: mdl-4394370
Subject(s)
Antihypertensive Agents/antagonists & inhibitors , Chlorpheniramine/pharmacology , Drug Antagonism , Guanidines/antagonists & inhibitors , Quaternary Ammonium Compounds/pharmacology , Sympathomimetics/pharmacology , Amino Alcohols/pharmacology , Blood Pressure , Female , Humans , Hypertension/chemically induced , Hypertension/drug therapy , Methyldopa/therapeutic use , Middle Aged , Phenethylamines/pharmacology , Phenylpropanolamine/pharmacology
5.
Am J Med
; 47(2): 175-93, 1969 Aug.
Article
in English
| MEDLINE
| ID: mdl-4309110