ABSTRACT
Eighty-eight patients operated on for coronary heart disease were examined. Continuous irrigation of pericardial cavity with circulating cold solution in combination with antegrade cardioplegia was used in 53 patients, antegrade cardioplegia with external cooling of the heart by icy mass in the rest 35. Intensive external cooling provided a stable temperature of the myocardium during clamping of the aorta.
Subject(s)
Body Temperature , Coronary Artery Bypass , Heart Arrest, Induced/methods , Myocardium , Cardioplegic Solutions/administration & dosage , Cold Temperature , HumansABSTRACT
Forty-three patients operated on under conditions of aortocoronary bypass were examined. In 29 of them continuous circulation of cold solution in pericardial cavity was combined with antegrade cardioplegia. In 14 routine technique of external myocardial cooling with snow and antegrade crystalloid cardioplegia was employed. Intensive external cooling of the heard helped not only maintain a lower myocardial temperature but permitted also a reduction of temperature gradients between various myocardial sites. This was conducive to a better preservation of energy reserve and contractility of the myocardium.
Subject(s)
Coronary Artery Bypass/methods , Heart Arrest, Induced/methods , Anesthesia, Inhalation , Body Temperature , Heart/physiopathology , Heart Arrest, Induced/instrumentation , Hemodynamics , Humans , Middle Aged , Myocardial Ischemia/physiopathology , Myocardial Ischemia/surgeryABSTRACT
In 21 patients with coronary heart disease, a procedure of protecting the myocardium was used during cardiac surgeries via irrigation of the pericardial cavity with circulating cold solution in combination with cardioplegia into the aortic root. The application of the procedure maintained stable myocardial temperature from 10.26 +/- 1.55 to 11.99 +/- 1.95 degrees C, excluding excessive overcooling and premature warming. The procedure awaits further studies in terms of biochemical changes and morphology of the myocardium at various stages of surgery.